公开(公告)号：WO1996038468A1

公开(公告)日：1996-12-05

申请号：PCT/US1996005408

申请日：1996-04-17

Applicant: RESEARCH CORPORATION TECHNOLOGIES, INC.

Inventor： RESEARCH CORPORATION TECHNOLOGIES, INC. ,  SHARMA, Ajit ,  KARUPPIAH, Nadarajah

IPC: C07K01/113

CPC classification number: C07K1/1136

Abstract: A method for renaturing a denaturated protein is provided comprising contacting a solution or suspension of said denatured protein in a detergent-free liquid medium with an amount of a cyclodextrin effective to renature said protein, and optionally, recovering the renatured protein in essentially pure form.

Abstract translation: 提供了一种用于变性变性蛋白质的方法，包括将所述变性蛋白质的溶液或悬浮液与不含洗涤剂的液体培养基接触，所述溶液或悬浮液与一定量的能有效地使所述蛋白质复性的环糊精，和任选以基本上纯的形式回收复性蛋白质。

公开(公告)号：EP0871651A1

公开(公告)日：1998-10-21

申请号：EP96912895.0

申请日：1996-04-17

Applicant: Research Corporation Technologies, Inc

Inventor： SHARMA, Ajit ,  KARUPPIAH, Nadarajah

IPC: C07K1

CPC classification number: C07K1/1136

Abstract: A method for renaturing a denaturated protein is provided comprising contacting a solution or suspension of said denatured protein in a detergent-free liquid medium with an amount of a cyclodextrin effective to renature said protein, and optionally, recovering the renatured protein in essentially pure form.