公开(公告)号：WO1996041173A1

公开(公告)日：1996-12-19

申请号：PCT/US1996007936

申请日：1996-05-29

Applicant: RESEARCH CORPORATION TECHNOLOGIES, INC.

Inventor： RESEARCH CORPORATION TECHNOLOGIES, INC. ,  DARLING, Graham, D. ,  HEISLER, Seymour +di ,  STRANIX, Brent, R. ,  TURKEWITSCH, Petra ,  WANDELT, Barbara

IPC: G01N33/531

CPC classification number: G01N33/531 ,  G01N2600/00

Abstract: The present invention provides solid imprinted particles comprising recognition sites spaced on the surface thereof which selectively bind a preselected template compound (T), wherein said recognition sites are each defined by a shaped polymeric matrix conforming to the shape and size of T, comprising a unit of the formula -B-Det, wherein B is bound to the polymeric matrix and also comprises a functional group which reversibly binds to T, and Det is a moiety capable of generating a detectable signal which changes following binding of B to template compound T.

Abstract translation: 本发明提供固体印迹颗粒，其包含在其表面上间隔开的选择性结合预选模板化合物（T）的识别位点，其中所述识别位点各自由符合T的形状和尺寸的成形聚合物基质限定，包括单元 式-B-Det，其中B与聚合物基体结合，并且还包含可逆结合T的官能团，并且Det是能够产生在B与模板化合物T结合后发生变化的可检测信号的部分。