公开(公告)号：WO1994000408A1

公开(公告)日：1994-01-06

申请号：PCT/US1993005933

申请日：1993-06-22

Applicant: RESEARCH CORPORATION TECHNOLOGIES, INC.

Inventor： RESEARCH CORPORATION TECHNOLOGIES, INC. ,  PIRKLE, William, H. ,  WELCH, Christopher, J. ,  BOWEN, William, E. ,  YANG, Qing

IPC: C07B57/00

CPC classification number: C07C233/83 ,  B01J20/3204 ,  B01J20/3219 ,  B01J20/3227 ,  B01J20/3248 ,  B01J20/3251 ,  B01J20/3253 ,  C07B57/00 ,  C07C237/22

Abstract: A high performance chiral selector having formula (I) whereinAr is a monocyclic or ortho-fused polycyclic aromatic moiety having up to 10 ring carbon atoms, either of which may be unsubstituted or substituted with one or more C1 to C6 alkyl, C1 to C6 alkoxy, NO2, N(R5)3, CN, COOR6, SO3H and COR7 groups wherein R5, R6 and R7 are each independently hydrogen or C1 to C6 alkyl; R1 and R2 are each independently hydrogen, C1 to C6 alkyl or phenyl; R3 and R4 are each independently C1 to C12 alkyl or C2 to C12 alkenyl; and m and n are each independently zero or 1, said compound being an R or an S enantiomer or a mixture of R and S enantiomers.

Abstract translation: 具有式（I）的高性能手性选择剂，其中Ar是具有至多10个环碳原子的单环或邻 - 稠合多环芳族部分，其中任一个可以是未取代的或被一个或多个C 1至C 6烷基，C 1至C 6烷氧基 ，NO 2，N（R 5）3，CN，COOR 6，SO 3 H和COR 7基团，其中R 5，R 6和R 7各自独立地为氢或C 1至C 6烷基; R 1和R 2各自独立地为氢，C 1至C 6烷基或苯基; R 3和R 4各自独立地为C 1至C 12烷基或C 2至C 12烯基; 并且m和n各自独立地为0或1，所述化合物是R或S对映体或R和S对映异构体的混合物。