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1.发明授权Crystalline salts of (Z)-O-octadec-9-en-1-yl O,O-dihydrogen phosphorothioate 有权（Z）-O-十八碳-9-烯-1-基O，O-二硫代磷酸酯的结晶盐公开(公告)号：US09567288B2
公开(公告)日：2017-02-14
申请号：US14569383
申请日：2014-12-12
Applicant: RxBio Inc.
Inventor： Rama Krishna Reddy Singidi , Veeresh Gududuru , Mahmoud Mirmehrabi , Karin Emmons Thompson , Gabor Jozsef Tigyi , Charles Ryan Yates , Jurriaan Strobos
CPC classification number: C07C229/26 , C07B2200/13 , C07F9/203 , C07F9/205 , C07F9/206 , C07F9/2408
Abstract: Here provided are a salt of Z)—O-octadec-9-en-1-yl O,O-dihydrogen phosphorothioate with an L-lysine addition in crystalline form and methods of making and using the same.
Abstract translation: 这里提供的是Z）-O-十八碳-9-烯-1-基O，O-二硫代磷酸硫酸盐，其结晶形式为L-赖氨酸加成盐，以及制备和使用它们的方法。
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公开(公告)号：US20170226139A1
公开(公告)日：2017-08-10
申请号：US15429972
申请日：2017-02-10
Applicant: RxBio Inc.
Inventor： Rama Krishna Reddy Singidi , Veeresh Gududuru , Mahmoud Mirmehrabi , Karin Emmons Thompson , Gabor Jozsef Tigyi , Charles Ryan Yates , Jurriaan Strobos
IPC: C07F9/06 , C07C229/26
CPC classification number: C07F9/062 , C07B2200/13 , C07C229/26 , C07F9/203 , C07F9/205 , C07F9/206 , C07F9/2408
Abstract: Here provided are a salt of Z)—O-octadec-9-en-1-yl O,O-dihydrogen phosphorothioate with an L-lysine addition in crystalline form and methods of making and using the same.
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3.发明申请CRYSTALLINE SALTS OF (Z)-O-OCTADEC-9-EN-1-YL O,O-DIHYDROGEN PHOSPHOROTHIOATE 审中-公开（Z）-O-OCTADEC-9-EN-1-YL O，O-二氢磷酸盐的晶体沉淀公开(公告)号：US20150183726A1
公开(公告)日：2015-07-02
申请号：US14569383
申请日：2014-12-12
Applicant: RxBio Inc.
Inventor： Rama Krishna Reddy Singidi , Veeresh Gududuru , Mahmoud Mirmehrabi , Karin Emmons Thompson , Gabor Jozsef Tigyi , Charles Ryan Yates , Jurriaan Strobos
IPC: C07C229/26 , C07F9/201
CPC classification number: C07C229/26 , C07B2200/13 , C07F9/203 , C07F9/205 , C07F9/206 , C07F9/2408
Abstract: Here provided are a salt of Z)—O-octadec-9-en-1-yl O,O-dihydrogen phosphorothioate with an L-lysine addition in crystalline form and methods of making and using the same.
Abstract translation: 这里提供的是Z）-O-十八碳-9-烯-1-基O，O-二硫代磷酸硫酸盐，其结晶形式为L-赖氨酸加成盐，以及制备和使用它们的方法。
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