公开(公告)号：AU2023313051A1

公开(公告)日：2025-02-13

申请号：AU2023313051

申请日：2023-07-31

Applicant: SANIFIT THERAPEUTICS S A

Inventor： SALCEDO ROCA CAROLINA ,  PÉREZ FERRER MARÍA DEL MAR ,  FERRER REYNÉS MIQUEL DAVID ,  BASSISSI MOHAMAD FIRAS ,  SERRA COMAS CARME ,  CATENA RUIZ JUAN LORENZO ,  LLEBARIA SOLDEVILA AMADEU ,  PERELLÓ BESTARD JOAN

IPC: C07F9/117 ,  A61P9/00 ,  A61P19/00 ,  A61P43/00 ,  C07C35/16 ,  C07D201/00 ,  C07F7/18 ,  C07F9/6503 ,  C07F9/6509 ,  C07F9/6518 ,  C07F9/6574

Abstract: The present invention provides IP5 substituted compounds of general formula I, their methods of synthesis and their uses. The IP5 substituted compounds of the invention are characterized for having -O(alkyl)

公开(公告)号：CA3130735A1

公开(公告)日：2020-08-06

申请号：CA3130735

申请日：2020-01-30

Applicant: SANIFIT THERAPEUTICS S A

Inventor： BASSISSI MOHAMAD FIRAS ,  SALCEDO ROCA CAROLINA ,  PERELLO BESTARD JOAN ,  FERRER REYNES MIQUEL DAVID ,  PEREZ FERRER MARIA DEL MAR

IPC: A61K31/6615 ,  A61P9/10 ,  A61P13/12

Abstract: The present invention relates to inositol phosphates, analogs, derivatives and pharmaceutically acceptable salts thereof, for use in increasing tissular perfusion and/or oxygenation in a subject in need thereof, in particular peripheral arterial disease. The present invention also relates to pharmaceutical compositions comprising said inositol phosphates, analogs, derivatives and pharmaceutically acceptable salts thereof, and their use in increasing tissular perfusion and/or oxygenation and for treating and preventing peripheral arterial disease.

公开(公告)号：IL318651A

公开(公告)日：2025-03-01

申请号：IL31865125

申请日：2025-01-28

Applicant: SANIFIT THERAPEUTICS S A ,  SALCEDO ROCA CAROLINA ,  P?REZ FERRER MAR?A DEL MAR ,  FERRER REYN?S MIQUEL DAVID ,  SERRA COMAS CARME ,  CATENA RUIZ JUAN LORENZO ,  LLEBARIA SOLDEVILA AMADEU ,  PERELL? BESTARD JOAN ,  BASSISSI MOHAMAD FIRAS

Inventor： SALCEDO ROCA CAROLINA ,  P?REZ FERRER MAR?A DEL MAR ,  FERRER REYN?S MIQUEL DAVID ,  SERRA COMAS CARME ,  CATENA RUIZ JUAN LORENZO ,  LLEBARIA SOLDEVILA AMADEU ,  PERELL? BESTARD JOAN ,  BASSISSI MOHAMAD FIRAS

IPC: A61P19/00 ,  A61P43/00 ,  C07C35/16 ,  C07C43/188 ,  C07C43/196

Abstract: The present invention provides IP5 substituted compounds of general formula I, their methods of synthesis and their uses. The IP5 substituted compounds of the invention are characterized for having -O(alkyl)nX, and -O(alkyl)yCy(alkyl)y'-Z chains in positions R1, R2, R4, and R5. Also provided are methods, pharmaceutical compositions and formulations, methods of use, articles of manufacture, and kits for the treatment of diseases and conditions such as pathological crystallization-related diseases and conditions.

公开(公告)号：AU2023313374A1

公开(公告)日：2025-02-13

申请号：AU2023313374

申请日：2023-07-31

Applicant: SANIFIT THERAPEUTICS S A

Inventor： BASSISSI MOHAMAD FIRAS ,  BLASCO FERRER MARC ,  PÉREZ FERRER MARÍA DEL MAR ,  FERRER REYNÉS MIQUEL DAVID ,  SALCEDO ROCA CAROLINA ,  GOLD ALEXANDER M ,  PERELLÓ BESTARD JOAN

IPC: A61K31/6615 ,  A61P17/02 ,  A61P19/00 ,  A61P43/00

Abstract: The present invention provides IP4-4,6 substituted derivatives for use in the prevention, inhibition of progression, and treatment of (a) ectopic calcification and the consequences thereof, and (b) a disease and/or condition related to ectopic calcification and the consequences thereof. Also provided are methods, pharmaceutical compositions and formulations, methods of use, articles of manufacture, and kits for use in the prevention, inhibition of progression, and treatment of (a) ectopic calcification and the consequences thereof, and (b) a disease and/or condition related to ectopic calcification and the consequences thereof.

公开(公告)号：AU2020213713A1

公开(公告)日：2021-07-22

申请号：AU2020213713

申请日：2020-01-30

Applicant: SANIFIT THERAPEUTICS S A

Inventor： BASSISSI MOHAMAD FIRAS ,  SALCEDO ROCA CAROLINA ,  PERELLÓ BESTARD JOAN ,  FERRER REYNÉS MIQUEL DAVID ,  PÉREZ FERRER MARÍA DEL MAR

IPC: A61K31/6615 ,  A61P9/10 ,  A61P13/12

Abstract: The present invention relates to inositol phosphates, analogs, derivatives and pharmaceutically acceptable salts thereof, for use in increasing tissular perfusion and/or oxygenation in a subject in need thereof, in particular peripheral arterial disease. The present invention also relates to pharmaceutical compositions comprising said inositol phosphates, analogs, derivatives and pharmaceutically acceptable salts thereof, and their use in increasing tissular perfusion and/or oxygenation and for treating and preventing peripheral arterial disease.

公开(公告)号：AU2022212601A9

公开(公告)日：2025-04-10

申请号：AU2022212601

申请日：2022-01-31

Applicant: SANIFIT THERAPEUTICS S A

Inventor： PÉREZ FERRER MARÍA DEL MAR ,  FERRER REYNÉS MIQUEL DAVID ,  BASSISSI MOHAMAD FIRAS ,  SALCEDO ROCA CAROLINA ,  SERRA COMAS CARME ,  CATENA RUIZ JUAN LORENZO ,  LLEBARIA SOLDEVILA AMADEU ,  ORTEGA CASTRO JOAQUÍN ,  PERELLÓ BESTARD JOAN

IPC: C07F9/165 ,  A61K31/6615 ,  A61P19/00

Abstract: The present invention provides IP4-4,6 substituted derivatives, their methods of synthesis and their uses. In some aspects, the IP4-4,6 derivative is a compound of formula I wherein R

公开(公告)号：IL318658A

公开(公告)日：2025-03-01

申请号：IL31865825

申请日：2025-01-28

Applicant: SANIFIT THERAPEUTICS S A ,  BLASCO FERRER MARC ,  P?REZ FERRER MAR?A DEL MAR ,  FERRER REYN?S MIQUEL DAVID ,  SALCEDO ROCA CAROLINA ,  PERELL? BESTARD JOAN ,  BASSISSI MOHAMAD FIRAS ,  GOLD ALEXANDER M

Inventor： BLASCO FERRER MARC ,  P?REZ FERRER MAR?A DEL MAR ,  FERRER REYN?S MIQUEL DAVID ,  SALCEDO ROCA CAROLINA ,  PERELL? BESTARD JOAN ,  BASSISSI MOHAMAD FIRAS ,  GOLD ALEXANDER M

IPC: A61K31/6615 ,  A61P17/02 ,  A61P19/00 ,  A61P43/00

Abstract: The present invention provides IP4-4,6 substituted derivatives for use in the prevention, inhibition of progression, and treatment of (a) ectopic calcification and the consequences thereof, and (b) a disease and/or condition related to ectopic calcification and the consequences thereof. Also provided are methods, pharmaceutical compositions and formulations, methods of use, articles of manufacture, and kits for use in the prevention, inhibition of progression, and treatment of (a) ectopic calcification and the consequences thereof, and (b) a disease and/or condition related to ectopic calcification and the consequences thereof.