公开(公告)号：CA2989042C

公开(公告)日：2020-12-08

申请号：CA2989042

申请日：2016-06-13

Applicant: SASKATCHEWAN CANCER AGENCY

Inventor： CRANMER-SARGISON GAVIN ,  KUNDAPUR VIJAYANANDA

IPC: A61N5/00 ,  G02B27/30 ,  G21K1/02 ,  G21K1/04

Abstract: An apparatus for delivery of spatially fractionated radiation treatment to a patient, the apparatus comprising: a radiation source for generating an open radiation beam oriented along a beam axis and having photon energies up to and including a maximum photon energy greater than 0.5MV; a mini-beam collimator located in a path of the open radiation beam, the mini-beam collimator comprising a plurality of generally planar blades extending between an entrance aperture onto which the open beam impinges and an exit aperture, the mini-beam collimator interacting with the open radiation beam to produce an output beam emitted from the exit aperture, oriented along the beam axis and comprising a spatially fractionated mini-beam dose profile, the spatially fractionated mini-beam dose profile comprising: a plurality of dose peaks at which the dose is a local maximum, the dose peaks spaced apart from one another in a transverse direction that is transverse to the beam axis; and a plurality of dose valleys at which the dose is a local minimum, each dose valley located between a pair of transversely adjacent dose peaks.

公开(公告)号：CA2989042A1

公开(公告)日：2016-12-22

申请号：CA2989042

申请日：2016-06-13

Applicant: SASKATCHEWAN CANCER AGENCY

Inventor： CRANMER-SARGISON GAVIN ,  KUNDAPUR VIJAYANANDA

IPC: A61N5/00 ,  G02B27/30 ,  G21K1/02 ,  G21K1/04

Abstract: An apparatus for delivery of spatially fractionated radiation treatment to a patient, the apparatus comprising: a radiation source for generating an open radiation beam oriented along a beam axis and having photon energies up to and including a maximum photon energy greater than 0.5MV; a mini-beam collimator located in a path of the open radiation beam, the mini-beam collimator comprising a plurality of generally planar blades extending between an entrance aperture onto which the open beam impinges and an exit aperture, the mini-beam collimator interacting with the open radiation beam to produce an output beam emitted from the exit aperture, oriented along the beam axis and comprising a spatially fractionated mini-beam dose profile, the spatially fractionated mini-beam dose profile comprising: a plurality of dose peaks at which the dose is a local maximum, the dose peaks spaced apart from one another in a transverse direction that is transverse to the beam axis; and a plurality of dose valleys at which the dose is a local minimum, each dose valley located between a pair of transversely adjacent dose peaks.