-
公开(公告)号：JPS635028A
公开(公告)日：1988-01-11
申请号：JP15153687
申请日：1987-06-19
Applicant: SCLAVO SPA
Inventor： LATTANZI FILIPPO , VANNI RICCARDO
-
公开(公告)号：IT1238072B
公开(公告)日：1993-07-03
申请号：IT1911290
申请日：1990-01-19
Applicant: SCLAVO SPA
Inventor： LATTANZI FILIPPO , VANNI RICCARDO
Abstract: New pharmaceutical compositions containing a calcitonin as active principle and suitable for oral administration in the form of perbuccal and sublingual tablets are described, in which the tive principle is homogenized with a mixture of solid excipients, said excipients consisting of a diluent, a lubricant, a disintegrating agent in the case of sublingual tablets, and a binder in the case of perbuccal tablets. Said compositions enable the same pattern of hematic levels to be obtained for the same unit dose as obtainable by conventional intramuscular administration.
-
3.发明专利
公开(公告)号：GR3002765T3
公开(公告)日：1993-01-25
申请号：GR910401377
申请日：1991-09-19
Applicant: SCLAVO SPA
Inventor： LATTANZI FILIPPO , VANNI RICCARDO
Abstract: A new freeze-dried pharmaceutical composition for parenteral administration, which comprises a therapeutically effective amount of a calcitonin, as the active ingredient, and human albumin. The injectable solution which is obtained by dissolving the freeze-dried composition in a physiologically acceptable solvent is also described.
-
4.发明专利
公开(公告)号：IT9019112A1
公开(公告)日：1991-07-20
申请号：IT1911290
申请日：1990-01-19
Applicant: SCLAVO SPA
Inventor： CECCHETTIN MAURIZIO , LATTANZI FILIPPO , VANNI RICCARDO
-
公开(公告)号：IT9019112D0
公开(公告)日：1990-01-19
申请号：IT1911290
申请日：1990-01-19
Applicant: SCLAVO SPA
Inventor： LATTANZI FILIPPO , CECCHETTIN MAURIZIO , VANNI RICCARDO
Abstract: New pharmaceutical compositions containing a calcitonin as active principle and suitable for oral administration in the form of perbuccal and sublingual tablets are described, in which the tive principle is homogenized with a mixture of solid excipients, said excipients consisting of a diluent, a lubricant, a disintegrating agent in the case of sublingual tablets, and a binder in the case of perbuccal tablets. Said compositions enable the same pattern of hematic levels to be obtained for the same unit dose as obtainable by conventional intramuscular administration.
-
Patent Agency Ranking
公开(公告)号：IT8922410D0
公开(公告)日：1989-11-16
申请号：IT2241089
申请日：1989-11-16
Applicant: SCLAVO SPA
Inventor： LATTANZI FILIPPO , VANNI RICCARDO
Abstract: New formulations are described containing a calcitonin as active principle and suitable for rectal administration in the form of soft gelatin capsules, in which the active principle, possibly mixed with a stabilizer, is dispersed in a liquid vehicle consisting of a polyethyleneglycol or a mixture of polyethyleneglycols of different molecular weight which has the consistency of a homogeneous fluid at ambient temperature, and possibly a C2-C6 alcohol with at least 2 hydroxyl groups, and present in a weight quantity of less than 15%. Said formulations, which contain no absorption adjuvant, enable the same pattern of hematic levels to be obtained as obtainable by conventional intramuscular administration, for equal unit dosages. Moreover, the absence of water makes said formulations highly stable.
-
公开(公告)号：IT1237197B
公开(公告)日：1993-05-26
申请号：IT2241089
申请日：1989-11-16
Applicant: SCLAVO SPA
Inventor： LATTANZI FILIPPO , VANNI RICCARDO
Abstract: New formulations are described containing a calcitonin as active principle and suitable for rectal administration in the form of soft gelatin capsules, in which the active principle, possibly mixed with a stabilizer, is dispersed in a liquid vehicle consisting of a polyethyleneglycol or a mixture of polyethyleneglycols of different molecular weight which has the consistency of a homogeneous fluid at ambient temperature, and possibly a C2-C6 alcohol with at least 2 hydroxyl groups, and present in a weight quantity of less than 15%. Said formulations, which contain no absorption adjuvant, enable the same pattern of hematic levels to be obtained as obtainable by conventional intramuscular administration, for equal unit dosages. Moreover, the absence of water makes said formulations highly stable.
-
公开(公告)号：CA2034519A1
公开(公告)日：1991-07-20
申请号：CA2034519
申请日：1991-01-18
Applicant: SCLAVO SPA
Inventor： LATTANZI FILIPPO , CECCHETTIN MAURIZIO , VANNI RICCARDO
Abstract: PHARMACEUTICAL COMPOSITIONS AND DOSAGE FORMS FOR THE ORAL ADMINISTRATION OF CALCITONIN New pharmaceutical compositions containing a calcitonin as active principle and suitable for oral administration in the form of perbuccal and sublingual tablets are described, in which the tive principle is homogenized with a mixture of solid excipients, said excipients consisting of a diluent, a lubricant, a disintegrating agent in the case of sublingual tablets, and a binder in the case of perbuccal tablets. Said compositions enable the same pattern of hematic levels to be obtained for the same unit dose as obtainable by conventional intramuscular administration.
-
公开(公告)号：IT1248725B
公开(公告)日：1995-01-26
申请号：IT2061290
申请日：1990-06-12
Applicant: SCLAVO SPA
Inventor： LATTANZI FILIPPO , CESCHEL GIANFRANCO , VANNI RICCARDO
-
公开(公告)号：AT69384T
公开(公告)日：1991-11-15
申请号：AT88114598
申请日：1988-09-07
Applicant: SCLAVO SPA
Inventor： LATTANZI FILIPPO , VANNI RICCARDO
Abstract: New compositions containing a calcitonin as the active ingredient are described which are suitable for the intrarectal administration as soft gelatin capsules or microenemas, wherein the active principle, optionally admixed with a stabilizer, is dissolved in a liquid vehicle consisting of : a) at least 70 % by weight of a polyethylene or a polypropylene glycol or a mixture of polyethylene or polypropylene glycols with different molecular weights, having the consistency of a homogeneous fluid at room temperature, and b) less than 15 % by weight of a buffer in a pH range of from 4.5 to 6.5, and optionally c) less than 15 % by weight of an alcohol of 2 to 6 carbon atoms containing two or more hydroxy groups. The new compositions, which do not contain any absorption aid, give calcitonin plasma levels comparable to a conventional intramuscular administration.
-
-
-
-
-
-
-
-
-
Search Results
19
records
(took 0.023 seconds)
