公开(公告)号：NZ532221A

公开(公告)日：2005-07-29

申请号：NZ53222104

申请日：2004-04-08

Applicant: SERVIER LAB

Inventor： POISSONNIER-DURIEUX SOPHIE ,  WALLEZ VALERIE ,  GASNEREAU ANNE ,  YOUS SAID ,  LESIEUR DANIEL ,  DELAGRANGE PHILIPPE ,  ENARD PIERRE ,  BENNEJEAN CAROLINE ,  BOUTIN JEAN ALBERT ,  AUDINOT VALERIE

IPC: C07D217/14 ,  A61K31/472 ,  A61P1/00 ,  A61P3/02 ,  A61P3/04 ,  A61P3/10 ,  A61P9/00 ,  A61P15/00 ,  A61P25/00 ,  A61P25/02 ,  A61P25/06 ,  A61P25/08 ,  A61P25/16 ,  A61P25/20 ,  A61P25/22 ,  A61P25/24 ,  A61P25/28 ,  A61P35/00 ,  A61P37/02 ,  A61P43/00 ,  C07D217/16 ,  C07D217/24 ,  A61K31/4045 ,  A61P9/10 ,  A61P25/14 ,  A61P25/18 ,  C07D221/04

Abstract: Described is a compound of formula (I): wherein n is l, 2 or 3, A represents a group -NR-C(=Z)-R', -C(=Z)-N(R)-R', or a group -NR-C(=Z)-N(R')-R", wherein: Z represents a S or O; R and R", which may be identical or different, each represents a H or alkyl group; R' represents an alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkyl-alkyl, aryl, aryl-alkyl, heteroaryl or heteroaryl-alkyl group; X represents N or N-R1 wherein R1 represents a H or alkyl, cycloalkyl, cycloalkyl-alkyl, aryl, aroyl, aryl-alkyl, heteroaryl, heteroaroyl or heteroaryl-alkyl group; R2 represents an alkoxy, cycloalkoxy or cycloalkyl-alkoxy group Provided are processes for the preparation of compounds if the formula (I) and descriptions of their use in the preparation of medicaments for treatment of disorders of the melatoninergic system.