公开(公告)号：AR043009A1

公开(公告)日：2005-07-13

申请号：ARP040100321

申请日：2004-02-03

Applicant: SERVIER LAB

Inventor： GALLET SEBASTIEN ,  BERTHELOT PASCAL ,  LEBEGUE NICOLAS ,  FLOUQUET NATHALIE ,  CARATO PASCAL ,  HICKMAN JOHN ,  PIERRE ALAIN ,  PFEIFFER BRUNO ,  RENARD PIERRE

IPC: A61P35/00 ,  C07D291/08 ,  C07D498/04 ,  C07D515/04 ,  A61K31/55 ,  A61K31/553 ,  C07D221/00 ,  C07D291/00

Abstract: Reivindicación 1: Compuestos de fórmula (1), donde: un resto de grupo de fórmula (2), que son iguales o diferentes, representan un grupo benzo o pirido, entendiéndose que el átomo de nitrógeno del grupo pirido ocupa cualquiera de las posiciones 1 a 4 y 5 a 8 de los anillos, y cada uno de los grupos benzo o pirido está opcionalmente sustituido por uno o más grupos idénticos o diferentes seleccionados entre átomos de halógeno y los grupos hidroxi, alquilo C1-6) lineal o ramificado, alcoxi C1-6 lineal o ramificado, trihaloalquilo C1-6 lineal o ramificado, amino (opcionalmente sustituido por uno o más grupos alquilo C1-6 lineal o ramificado), nitro, acilo C1-6 lineal o ramificado y alquilendioxi C1-2; W representa >SO2 o >C=O; Y representa (CH2)n, un grupo alquenileno C2-6 o un grupo alquinileno C2-6, n representa cero o un entero en el cual 1 =

公开(公告)号：FR2850655A1

公开(公告)日：2004-08-06

申请号：FR0301180

申请日：2003-02-03

Applicant: SERVIER LAB

Inventor： GALLET SEBASTIEN ,  BERTHELOT PASCAL ,  LEBEGUE NICOLAS ,  FLOUQUET NATHALIE ,  CARATO PASCAL ,  HICKMAN JOHN ,  PIERRE ALAIN ,  PFEIFFER BRUNO ,  RENARD PIERRE

IPC: A61P35/00 ,  C07D291/08 ,  C07D498/04 ,  C07D515/04 ,  A61K31/553 ,  A61K31/554

公开(公告)号：BRPI0407215A

公开(公告)日：2006-01-24

申请号：BRPI0407215

申请日：2004-02-03

Applicant: SERVIER LAB

Inventor： GALLET SEBASTIEN ,  BERTHELOT PASCAL ,  LEBEGUE NICOLAS ,  FLOUQUET NATHALIE ,  CARATO PASCAL ,  HICKMAN JOHN ,  PIERRE ALAIN ,  PFEIFFER BRUNO ,  RENARD PIERRE

IPC: A61P35/00 ,  C07D513/04 ,  C07D515/04 ,  A61K31/55

Abstract: A compound of formula (I): wherein: represents benzo or pyrido, optionally fused in the 2-3, 3-4 or 4-5 position to a phenyl, (C 4 -C 8 )cycloalkyl or heterocyclic group, which may be optionally substituted, W represents X-Y or Y-X, wherein: X represents and Y represents oxygen or N-R 3 , n represents zero or an integer from 1 to 6, G, R 1 , R 2 and R 3 are as defined in the description, its enantiomers and diastereoisomers, and addition salts thereof with a pharmaceutically acceptable acid or base, and medicinal products containing the same which are useful for the treatment of cancerous diseases.

公开(公告)号：NO20054092A

公开(公告)日：2005-09-02

申请号：NO20054092

申请日：2005-09-02

Applicant: SERVIER LAB

Inventor： PIERRE ALAIN ,  RENARD PIERRE ,  CARATO PASCAL ,  PFEIFFER BRUNO ,  LEBEGUE NICOLAS ,  BERTHELOT PASCAL ,  GALLET SEBASTIAN ,  FLOUQUET NATHALIE ,  HICKMAN JOHN

IPC: A61P35/00 ,  C07D513/04 ,  C07D515/04 ,  A61K31/55

CPC classification number: C07D513/04 ,  C07D515/04

公开(公告)号：MA27576A1

公开(公告)日：2005-10-03

申请号：MA28377

申请日：2005-07-11

Applicant: SERVIER LAB

Inventor： GALLET SEBASTIEN ,  BERTHELOT PASCAL ,  LEBEGUE NICOLAS ,  FLOUQUET NATHALIE ,  CARATO PASCAL ,  HICKMAN JOHN ,  PIERRE ALAIN ,  PFEIFFER BRUNO ,  RENARD PIERRE

IPC: A61P35/00 ,  C07D513/04 ,  C07D515/04 ,  A61K31/55

Abstract: NOUVEAUX DERIVES D'AZEPINES TRICYCLIQUES, LEUR PROCEDE DE PREPARATION ET LES COMPOSITIONS PHARMACEUTIQUES QUI LES CONTIENNENT Composé de formule (I) : dans laquelle : - représente un groupement benzo ou pyrido, éventuellement fusionné en position 2-3, 3-4, ou 4-5, et éventuellement substitué, - W représente un groupement X„Y ou Y„X avec : X représentant un groupement et Y représentant un atome d'oxygène ou un groupement N-R3, - n représente zéro ou un entier tel que 1 (

公开(公告)号：CA2513059A1

公开(公告)日：2004-08-19

申请号：CA2513059

申请日：2004-02-03

Applicant: SERVIER LAB

Inventor： CARATO PASCAL ,  FLOUQUET NATHALIE ,  PIERRE ALAIN ,  BERTHELOT PASCAL ,  PFEIFFER BRUNO ,  RENARD PIERRE ,  LEBEGUE NICOLAS ,  HICKMAN JOHN ,  GALLET SEBASTIEN

IPC: A61P35/00 ,  C07D513/04 ,  C07D515/04 ,  A61K31/55

公开(公告)号：FR2850654A1

公开(公告)日：2004-08-06

申请号：FR0301181

申请日：2003-02-03

Applicant: SERVIER LAB

Inventor： GALLET SEBASTIEN ,  BERTHELOT PASCAL ,  LEBEGUE NICOLAS ,  FLOUQUET NATHALIE ,  CARATO PASCAL ,  HICKMAN JOHN ,  PIERRE ALAIN ,  PFEIFFER BRUNO ,  RENARD PIERRE

IPC: A61P35/00 ,  C07D513/04 ,  C07D515/04 ,  A61K31/554

Abstract: A compound of formula (I): wherein: represents benzo or pyrido, optionally fused in the 2-3, 3-4 or 4-5 position to a phenyl, (C 4 -C 8 )cycloalkyl or heterocyclic group, which may be optionally substituted, W represents X-Y or Y-X, wherein: X represents and Y represents oxygen or N-R 3 , n represents zero or an integer from 1 to 6, G, R 1 , R 2 and R 3 are as defined in the description, its enantiomers and diastereoisomers, and addition salts thereof with a pharmaceutically acceptable acid or base, and medicinal products containing the same which are useful for the treatment of cancerous diseases.

公开(公告)号：ZA200505430B

公开(公告)日：2006-09-27

申请号：ZA200505430

申请日：2004-02-03

Applicant: SERVIER LAB

Inventor： GALLET SEBASTIEN ,  BERTHELOT PASCAL ,  LEBEGUE NICOLAS ,  FLOUQUET NATHALIE ,  CARATO PASCAL ,  HICKMAN JPHN ,  PIERRE ALAIN ,  PFEIFFER BRUNO ,  RENARD PIERRE

IPC: A61K20060101 ,  A61P35/00 ,  C07D20060101 ,  C07D513/04 ,  C07D515/04

Abstract: A compound of formula (I): wherein: represents benzo or pyrido, optionally fused in the 2-3, 3-4 or 4-5 position to a phenyl, (C 4 -C 8 )cycloalkyl or heterocyclic group, which may be optionally substituted, W represents X-Y or Y-X, wherein: X represents and Y represents oxygen or N-R 3 , n represents zero or an integer from 1 to 6, G, R 1 , R 2 and R 3 are as defined in the description, its enantiomers and diastereoisomers, and addition salts thereof with a pharmaceutically acceptable acid or base, and medicinal products containing the same which are useful for the treatment of cancerous diseases.

公开(公告)号：FR2850655B1

公开(公告)日：2005-03-11

申请号：FR0301180

申请日：2003-02-03

Applicant: SERVIER LAB

Inventor： GALLET SEBASTIEN ,  BERTHELOT PASCAL ,  LEBEGUE NICOLAS ,  FLOUQUET NATHALIE ,  CARATO PASCAL ,  HICKMAN JOHN ,  PIERRE ALAIN ,  PFEIFFER BRUNO ,  RENARD PIERRE

IPC: A61P35/00 ,  C07D291/08 ,  C07D498/04 ,  C07D515/04 ,  A61K31/553 ,  A61K31/554

公开(公告)号：AU2004208890A1

公开(公告)日：2004-08-19

申请号：AU2004208890

申请日：2004-02-03

Applicant: SERVIER LAB

Inventor： HICKMAN JOHN ,  PIERRE ALAIN ,  PFEIFFER BRUNO ,  RENARD PIERRE ,  GALLET SEBASTIEN ,  BERTHELOT PASCAL ,  LEBEGUE NICOLAS ,  FLOUQUET NATHALIE ,  CARATO PASCAL

IPC: A61P35/00 ,  C07D513/04 ,  C07D515/04 ,  A61K31/55

Abstract: A compound of formula (I): wherein: represents benzo or pyrido, optionally fused in the 2-3, 3-4 or 4-5 position to a phenyl, (C 4 -C 8 )cycloalkyl or heterocyclic group, which may be optionally substituted, W represents X-Y or Y-X, wherein: X represents and Y represents oxygen or N-R 3 , n represents zero or an integer from 1 to 6, G, R 1 , R 2 and R 3 are as defined in the description, its enantiomers and diastereoisomers, and addition salts thereof with a pharmaceutically acceptable acid or base, and medicinal products containing the same which are useful for the treatment of cancerous diseases.