公开(公告)号：CY2160B1

公开(公告)日：2002-08-23

申请号：CY0000003

申请日：2000-03-01

Applicant: SERVIER LAB

Inventor： BRION JEAN-DANIEL ,  THAL CLAUDE ,  DEMUYNCK LUC ,  PARMENTIER JEAN-GILLES ,  LEPAGNOL JEAN ,  LESTAGE PIERRE ,  PUJOL JEAN-FRANCOIS ,  SCHMITT PASCAL ,  POTIER PIERRE

IPC: C07D471/06 ,  A61K31/435 ,  A61P25/00 ,  A61P25/20 ,  A61P25/24 ,  A61P25/26 ,  A61P25/28 ,  A61P43/00 ,  C07D461/00 ,  C07D471/22 ,  A61K31/495

Abstract: Compounds of general formula (I): in which A represents a divalent radical chosen from and R1, R2, R3, R4, R5, R6, R7, R8, R9 and Z are as defined in the description. Medicaments.

公开(公告)号：PT937043E

公开(公告)日：2002-07-31

申请号：PT97948974

申请日：1997-12-02

Applicant: SERVIER LAB

Inventor： LEPAGNOL JEAN ,  MARAZANO CHRISTIAN ,  DELPHINE COMPERE ,  DAS C BHUPESH

IPC: A61K31/44 ,  A61P25/14 ,  A61P25/16 ,  A61P25/28 ,  C07D211/70 ,  A61K31/445

Abstract: The invention relates to compounds of general formula (I):in which R, R1, R2, X and Y are as defined in the description, their geometrical and/or optical isomers, and their addition salts with a pharmaceutically-acceptable acid or base, as well as to medicaments containing the same.

公开(公告)号：PL189372B1

公开(公告)日：2005-07-29

申请号：PL33381397

申请日：1997-12-02

Applicant: SERVIER LAB

Inventor： MARAZANO CHRISTIAN ,  COMPERE DELPHINE ,  DAS BHUPESH CHANDRA ,  LEPAGNOL JEAN

IPC: A61K31/44 ,  A61P25/14 ,  A61P25/16 ,  A61P25/28 ,  C07D211/70

Abstract: The invention relates to compounds of general formula (I):in which R, R1, R2, X and Y are as defined in the description, their geometrical and/or optical isomers, and their addition salts with a pharmaceutically-acceptable acid or base, as well as to medicaments containing the same.

公开(公告)号：ES2172023T3

公开(公告)日：2002-09-16

申请号：ES97948974

申请日：1997-12-02

Applicant: SERVIER LAB

Inventor： MARAZANO CHRISTIAN ,  COMPERE DELPHINE ,  DAS C BHUPESH ,  LEPAGNOL JEAN

IPC: A61K31/44 ,  A61P25/14 ,  A61P25/16 ,  A61P25/28 ,  C07D211/70 ,  A61K31/445

Abstract: The invention relates to compounds of general formula (I):in which R, R1, R2, X and Y are as defined in the description, their geometrical and/or optical isomers, and their addition salts with a pharmaceutically-acceptable acid or base, as well as to medicaments containing the same.

公开(公告)号：DE69710909D1

公开(公告)日：2002-04-11

申请号：DE69710909

申请日：1997-12-02

Applicant: SERVIER LAB

Inventor： MARAZANO CHRISTIAN ,  COMPERE DELPHINE ,  DAS BHUPESH ,  LEPAGNOL JEAN

IPC: A61K31/44 ,  A61P25/14 ,  A61P25/16 ,  A61P25/28 ,  C07D211/70 ,  A61K31/445

Abstract: The invention relates to compounds of general formula (I):in which R, R1, R2, X and Y are as defined in the description, their geometrical and/or optical isomers, and their addition salts with a pharmaceutically-acceptable acid or base, as well as to medicaments containing the same.

公开(公告)号：AT214051T

公开(公告)日：2002-03-15

申请号：AT97948974

申请日：1997-12-02

Applicant: SERVIER LAB

Inventor： MARAZANO CHRISTIAN ,  COMPERE DELPHINE ,  DAS C BHUPESH ,  LEPAGNOL JEAN

IPC: A61K31/44 ,  A61P25/14 ,  A61P25/16 ,  A61P25/28 ,  C07D211/70 ,  A61K31/445

Abstract: The invention relates to compounds of general formula (I):in which R, R1, R2, X and Y are as defined in the description, their geometrical and/or optical isomers, and their addition salts with a pharmaceutically-acceptable acid or base, as well as to medicaments containing the same.

公开(公告)号：AU2491395A

公开(公告)日：1996-01-25

申请号：AU2491395

申请日：1995-07-10

Applicant: SERVIER LAB

Inventor： CORDI ALEX ,  SPEDDING MICHAEL ,  SERKIZ BERNARD ,  LEPAGNOL JEAN ,  DESOS PATRICE ,  MORAIN PHILIPPE

IPC: A61K31/54 ,  A61K31/549 ,  A61P25/00 ,  A61P25/18 ,  A61P25/20 ,  A61P25/28 ,  A61P43/00 ,  C07B53/00 ,  C07B57/00 ,  C07B61/00 ,  C07D513/04

Abstract: (3aS)-5,5-Dioxo- 2,3,3a,4-tetrahydro- 1H-pyrrolo (2,1-c) (1,2,4) benzothiadiazine of formula (I) and its salts are new.

公开(公告)号：AU5795694A

公开(公告)日：1994-09-29

申请号：AU5795694

申请日：1994-03-22

Applicant: SERVIER LAB

Inventor： NANTEUIL GUILLAUME DE ,  PORTEVIN BERNARD ,  REMOND GEORGES ,  LEPAGNOL JEAN ,  HEIDET VERONIQUE

IPC: A61K31/40 ,  A61K31/401 ,  A61K31/42 ,  A61K31/425 ,  A61K31/435 ,  A61K31/4427 ,  A61K31/445 ,  A61K31/47 ,  A61P9/00 ,  A61P25/00 ,  A61P25/20 ,  A61P25/24 ,  A61P25/26 ,  A61P25/28 ,  A61P43/00 ,  C07D209/42 ,  C07D401/06 ,  C07D403/06 ,  C07D409/08 ,  C07D413/06 ,  C07D417/06 ,  C07D453/02 ,  C07D453/06

Abstract: The invention relates to the compounds of formula (I): in which: A represents, with the carbon and nitrogen atoms to which it is attached, a heterocycle, B represents, with the nitrogen atom to which it is attached, a heterocycle, n is equal to 1, 2, 3 or 4, R represents a phenyl group substituted by at least one halogen atom or one alkyl, hydroxyl, alkoxy, trifluoromethyl, nitro, amino, cyano, carboxyl or alkoxycarbonyl group, a benzyl group, a thienyl group or a pyridyl group. Medicaments.

公开(公告)号：FI111951B

公开(公告)日：2003-10-15

申请号：FI953384

申请日：1995-07-11

Applicant: SERVIER LAB

Inventor： CORDI ALEX ,  SPEDDING MICHAEL ,  SERKIZ BERNARD ,  LEPAGNOL JEAN ,  DESOS PATRICE ,  MORAIN PHILIPPE

IPC: A61K31/54 ,  A61K31/549 ,  A61P25/00 ,  A61P25/18 ,  A61P25/20 ,  A61P25/28 ,  A61P43/00 ,  C07B53/00 ,  C07B57/00 ,  C07B61/00 ,  C07D513/04

Abstract: (3aS)-5,5-Dioxo- 2,3,3a,4-tetrahydro- 1H-pyrrolo (2,1-c) (1,2,4) benzothiadiazine of formula (I) and its salts are new.

公开(公告)号：DE69710909T2

公开(公告)日：2002-11-07

申请号：DE69710909

申请日：1997-12-02

Applicant: SERVIER LAB

Inventor： MARAZANO CHRISTIAN ,  COMPERE DELPHINE ,  DAS BHUPESH ,  LEPAGNOL JEAN

IPC: A61K31/44 ,  A61P25/14 ,  A61P25/16 ,  A61P25/28 ,  C07D211/70 ,  A61K31/445

Abstract: The invention relates to compounds of general formula (I):in which R, R1, R2, X and Y are as defined in the description, their geometrical and/or optical isomers, and their addition salts with a pharmaceutically-acceptable acid or base, as well as to medicaments containing the same.