公开(公告)号：JPS63271155A

公开(公告)日：1988-11-09

申请号：JP10780887

申请日：1987-04-28

Applicant: SHIMADZU CORP

Inventor： ARASHIMA HIDEYOSHI

IPC: G01N27/28 ,  G01N27/30 ,  G01N27/401

Abstract: PURPOSE:To prevent inflow of a reference electrode liquid to a measuring electrode cell by increasing the capacity of a pipeline between a liquid junction and reference cell to the capacity larger than the capacity up to a valve provided to excess sample discharge pipes. CONSTITUTION:A pipe 1 for controlling the amt. of a sample is set slightly longer than the length corresponding to the amt. of the sample between a sample injection port 2 and the measuring electrode cell 3. A branch pipe 4 is connected to the point coinciding with the specified amt. of the sample from the port 2 and the excess sample discharge pipes 6, 6' are connected via the valve 5. A 1st pump 9 which is driven by a motor 8 and a 2nd pump 14 which connects the discharge side of the measuring electrode cell 3 and is communicated with a reference electrode liquid tank 13 via a reference electrode cell 7 are connected via a branch pipe 11. The capacity of the pipeline from the branch pipe 11 to the measuring electrode cell 3 is so set as to be larger than the capacity of the pipeline from the branch pipe 4 up to the valve 5. The contact of the backflowing reference electrolyte with the measuring electrode 3a at the time of discharging the excess sample is thereby prevented.

公开(公告)号：JPH02143143A

公开(公告)日：1990-06-01

申请号：JP29888688

申请日：1988-11-25

Applicant: SHIMADZU CORP

Inventor： TSUNASAWA YOSHIO ,  ARASHIMA HIDEYOSHI

IPC: G01N21/11

Abstract: PURPOSE:To accurately suck a sample by an expected suction amount and to utilize all prepared samples effectively by providing an arrival detector to a flow cell conduit, adjusting the time when calibrating liquid is sucked to the arrival detector, and calculating a suction capacity coefficient. CONSTITUTION:The tube 6 of the liquid sensor 10 of a flow cell device used for a spectrophotometer, etc., is a transparent tube, which is run through the circular hole of the black case 14 of the liquid sensor 10; and a phototransistor TR 18 is arranged in the case 14 at the tube 6 at right angles to the light incidence direction of a light emitting diode 16. When the tube 6 of this sensor 10 is filled with transparent liquid, light from the diode 16 is incident on the TR 18 through the tube 6 and when the liquid absorbs the light, no light arrives at the TR 18, whose output signal goes up to high level, so that the TR 18 turns on. Then, a pump 8 is turned on and off to control the suction of the calibrating liquid and sample to the flow cell 2, and the capacity Vo for calculating the suction capacity coefficient K in a calibrating stroke is the capacity from the tip 4a of the suction tube 4 to the sensor 10.

公开(公告)号：JPH10332658A

公开(公告)日：1998-12-18

申请号：JP7379698

申请日：1998-03-23

Applicant: WAKO PURE CHEM IND LTD ,  SHIMADZU CORP

Inventor： NAKAMURA KENJI ,  SATOMURA SHINJI ,  HAYASHI MASAYOSHI ,  ARASHIMA HIDEYOSHI ,  OKUYAMA TETSUSHI ,  HANABUSA NOBUHIRO ,  TANIMIZU HIROHARU

IPC: G01N30/00 ,  G01N30/40

Abstract: PROBLEM TO BE SOLVED: To provide a method in which an adsorbate can be separated from an eluate many numbers of times by a method wherein a liquid sample is introduced into a separating implement from a direction opposite to its diluting direction, impurities are eluted completely from an object to be measured, the other is adsorbed by an adsorbent and the adsorbate is separated and eluted from the eluate. SOLUTION: The pressure at the inside of a column is decreased by a pump, a liquid sample is sucked from a sample introduction pipe in a direction opposite to its eluting direction, and the sample is adsorbed by an adsorbent almost totally. Then, an eluate which is adapted to the adsorbent is made to flow to the eluting direction, the eluate is introduced into the column, the inside of the column is pressurized by the pump, and the eluate is eluted from an eluting tip together with the liquid sample. When impurities are separated, an adsorbent which adsorbs the whole or the grater part of an object to be measured is used, the liquid sample is sucked from the eluting tip, an eluate which does not elute the adsorbed sample to be measured is sucked from the eluting tip so as to be pressurized, the eluate is made to flow to the eluting direction, and the greater part of an undissolved substance is removed. Then, an eluate which elutes the sample to be measured is sucked from the eluting tip so as to be pressurized, the eluate is made to flow to the eluting direction, and the object to be measured is extracted.

公开(公告)号：JPH03219312A

公开(公告)日：1991-09-26

申请号：JP1647590

申请日：1990-01-25

Applicant: SHIMADZU CORP

Inventor： ARASHIMA HIDEYOSHI

IPC: G05D23/20

Abstract: PURPOSE:To supply a stable voltage by selecting a positive reference voltage (RV), a negative RV and a zero RV by a RV selecting circuit, and supplying always the constant voltage to a cold heating element based upon control operation between an amplifier and a 1st transistor (TR) or a 2nd TR. CONSTITUTION:When the RV selecting circuit 4 selects the positive RV, the positive RF is impressed to the non-inverted input terminal of the amplifier 5, the 1st TR Q1 is driven in a non-saturated area and the voltage of the inverted into terminal of the amplifier 5 is controlled so as to be identical with the voltage of the non-inverted input terminal independently of a voltage value applied from a power supply circuit. Thereby, the voltage is impressed to one terminal of the cold heating element and the positive RV is applied as the impression voltage. When th circuit 4 selects the negative RV, the negative RV is impressed to the non-inverted input terminal of the amplifier 5, the 2nd TR Q2 is driven in the non-saturated area by the output from the amplifier 5 and the voltage of the inverted input terminal of the amplifier is controlled so as to be identical with the voltage of the non-inverted input terminal independently of the voltage value applied from the power supply circuit. Consequently, the stable voltage can be supplied.

公开(公告)号：JP2518434B2

公开(公告)日：1996-07-24

申请号：JP1647590

申请日：1990-01-25

Applicant: SHIMADZU CORP

Inventor： ARASHIMA HIDEYOSHI

IPC: G05D23/20

公开(公告)号：JPH0266441A

公开(公告)日：1990-03-06

申请号：JP21803688

申请日：1988-08-31

Applicant: SHIMADZU CORP

Inventor： ARASHIMA HIDEYOSHI

IPC: G01N27/416

Abstract: PURPOSE:To allow continuous and long-term measurement by measuring the pressure of liquid flow and the electrode potential by a liquid film ion selective electrode of the liquid flow, determining the fluctuation in the pressure of the liquid flow and the fluctuation in the electrode potential and measuring the service limit. CONSTITUTION:The liquid film ion selective electrode 2 is provided in contact with a flow passage 3 and a peristaltic pump 5 is provided to the discharge side of the flow passage 3. The pressure of the liquid flow in the flow passage 3 and the electrode potential by the electrode 2 of the liquid flow are measured at the plural points of the time. The fluctuation in the pressure of the liquid flow and the fluctuation in the electrode potential of the electrode 2 appearing in synchronization with the above- mentioned fluctuation in the pressure are determined. The liquid feed of the pump 5 is decreased to keep the fluctuation value of the electrode potential within the threshold value where the fluctuation value of the electrode potential exceeds the threshold value. The electrode potential of the liquid flow is thus measured. The deterioration of the sensitive film of the electrode 2 is determined in association with the measured value thereof and the effective use of the sensitive film within the service limit thereof is possible.

公开(公告)号：JPH01263552A

公开(公告)日：1989-10-20

申请号：JP9318688

申请日：1988-04-15

Applicant: SHIMADZU CORP

Inventor： ARASHIMA HIDEYOSHI

IPC: G01N27/30 ,  G01N27/416

Abstract: PURPOSE:To perform highly reliable measurement, by a method wherein an airtight tank is provided between a liquid junction and a reference electrode and an air bubble is collected in a reference liquid supply pipeline while the pipeline is closes and a sample suction pump is operated to expand and discharge the air bubbles out of the tank. CONSTITUTION:When a solenoid valve 3 is closed while a solenoid valve 9 is opened and a pump 6 is driven to inject a sample from a sample injection port 2, the sample reaches a branch part 5 through an ion selective electrode 1 and a reference liquid reaches said branch part from a tank 10 through a reference electrode 11 and both of them form a liquid junction. By this mechanism, the potential difference between the electrodes 1, 11 corresponding to the ion component contained in the sample is outputted from said electrodes 1, 11. In this state, the air bubble generated in a reference electrode liquid supply flow passage 8 is collected in a tank 12 to be detected by an air bubble detector 13 and a control circuit 14 stops analytical work on the basis of the signal from the detector 13 and closes the valves 3, 9 and the injection port 2 to stop the pump 6. By this method, the flow passage 8 becomes negative pressure and the air bubble in the tank 12 expands to be discharged out of the system along with the reference liquid through the flow passage 8 and the valve 9.

公开(公告)号：JP2001041891A

公开(公告)日：2001-02-16

申请号：JP21649899

申请日：1999-07-30

Applicant: SHIMADZU CORP

Inventor： SUZUKI KAZUHIRO ,  ARASHIMA HIDEYOSHI

IPC: G01N21/64 ,  G01N21/75 ,  G01N21/78

Abstract: PROBLEM TO BE SOLVED: To obtain a fluorescence detecting apparatus capable of detecting fluorescence corresponding to the quantity thereof with proper sensitivity without performing re-detection. SOLUTION: A negative high voltage generating circuit 12 is sequentially changed over from a resistance circuit 14 high in voltage dividing resistance value to a resistance circuit 14 low in voltage dividing resistance value and the magnification ratio of a photomultiplier tube 10 is sequentially changed over a plurality of ranges. A data processing part 8 stores the output of the photomultiplier tube 10 inputted through an amplifier 4 and an A/D converter 6 corresponding to the ranges. After measurement is completed, the data processing part 8 looks time-series data in order from a range high in sensitivity to select a range wherein all of photometric data within a time-series are not saturated and calculates change quantity from the time-series data of the selected range to calculate the conversion coefficient from the selected range to a reference magnification ratio wherein a calibration curve is prepared and multiplies the change quantity by the conversion coefficient to set the change quantity in the range of the reference magnification ratio and subsequently uses the calibration curve to calculate a quantitative value.

公开(公告)号：JPH1073559A

公开(公告)日：1998-03-17

申请号：JP23065696

申请日：1996-08-30

Applicant: SHIMADZU CORP

Inventor： ARASHIMA HIDEYOSHI

IPC: G01N27/28

Abstract: PROBLEM TO BE SOLVED: To provide a novel electrolyte analyzer in which the mixing efficiency does not lower even if a mixer is eliminated or reduced in size. SOLUTION: At first, a sample probe 5 is shifted to any specimen case 8 on a sample tray 7 and solenoid valves 9, 14 are opened while solenoid valves 11, 16 are closed to lower the syringes of syringe pumps 10, 13 thus feeding a specimen into pumps 10, 13, respectively. The sample probe 5 is then shifted to the specimen injection port 2 of a specimen pot 1 and the solenoid valves 9, 16 are opened while the solenoid valves 11, 14 are closed to elevate the syringes of the pumps 10, 13. Consequently, the specimen and a diluting liquid are fed into the specimen pot 1 and mixed at a specified ratio. In this regard, the sample probe 5 is subjected to micro reciprocal motion (such that the forward end of the sample probe 5 moved up and down in the specimen pot 1) by means of a probe motor in order to enhance the mixing efficiency.

公开(公告)号：JPH04138366A

公开(公告)日：1992-05-12

申请号：JP26157290

申请日：1990-09-29

Applicant: SHIMADZU CORP

Inventor： ARASHIMA HIDEYOSHI

IPC: G01N35/00

Abstract: PURPOSE:To automatically perform the self-evaluation of analytical capacity by measuring a group of samples twice by changing a measuring order and calculating autocorrelation with respect to the measured result. CONSTITUTION:In the first measurement, (N) samples arranged to a sample holding part 2 are successively measured from the first sample by an analyzing part 4 and the measured results are stored in a memory part 8 corresponding to sample numbers. In the second measurement, for example, random numbers are generated in a sample selecting part 6 so as to defer the order of the samples and the measuring order of the samples is differentiated to measure the samples in the same way to store the measured results in the memory part 8. After the second measurement, an operation part 10 calculates a regres sion equation by the regression analysis based on the measured values to calcu late autocorrelation. Then, the state of the analytical capacity of the apparatus is judged on the basis of the preset reference value of autocorrelation and the evaluating measurement thereof is automatically carried out. By this constitu tion, the reliability of the apparatus is confirmed for a long period of time to be kept.