公开(公告)号：CA3029926C

公开(公告)日：2023-01-03

申请号：CA3029926

申请日：2016-07-25

Applicant: SHIZUOKA PREFECTURE

Inventor： MOCHIZUKI TOHRU ,  OHSHIMA KEIICHI ,  HATAKEYAMA KEIICHI ,  YAMAGUCHI KEN ,  NAKAO KANAKO

IPC: G01N33/574

Abstract: An object of the present invention is to provide a method for collecting highly accurate data for diagnosis, useful in diagnosing the presence or absence of extrahepatic bile duct carcinoma, intrahepatic bile duct carcinoma, or gallbladder carcinoma, and a kit for diagnosis. When the concentration of CEACAM1 in a blood sample collected from a test subject is detected using a kit for diagnosis comprising an antibody specifically binding to CEACAM1 or a labeled product thereof, or the like and the CEACAM1 concentration is higher than the concentration of CEACAM1 in a blood sample derived from a non-carcinoma control subject or higher than a certain threshold value (cutoff value), data can be collected for diagnosing the test subject as having a high possibility of having extrahepatic bile duct carcinoma, intrahepatic bile duct carcinoma, or gallbladder carcinoma.

公开(公告)号：CA3029926A1

公开(公告)日：2018-02-01

申请号：CA3029926

申请日：2016-07-25

Applicant: SHIZUOKA PREFECTURE

Inventor： MOCHIZUKI TOHRU ,  OHSHIMA KEIICHI ,  HATAKEYAMA KEIICHI ,  YAMAGUCHI KEN ,  NAKAO KANAKO

IPC: G01N33/574

Abstract: The present invention addresses the problem of providing a method for collecting highly accurate diagnostic data and a diagnostic kit, both of which are useful for the diagnosis of the occurrence of extrahepatic bile duct cancer, intrahepatic bile duct cancer or gallbladder cancer. The concentration of CEACAM1 in a blood sample collected from a subject is detected using a diagnostic kit including an antibody capable of binding specifically to CEACAM1 or a labeled product of the antibody or the like, whereby it becomes possible to obtain data from which it is diagnosed that a subject is highly probably suffering from extrahepatic bile duct cancer, intrahepatic bile duct cancer or gallbladder cancer when the concentration of CEACAM1 is higher than that in a blood sample from a normal person or is higher than a given threshold value (cut-off value).

公开(公告)号：JP2008210206A

公开(公告)日：2008-09-11

申请号：JP2007046926

申请日：2007-02-27

Applicant: Meiden Software Corp ,  Shizuoka Prefecture ,  明電ソフトウエア株式会社 ,  静岡県

Inventor： YAMAGUCHI KEN ,  ISHIKAWA MUTSUMI ,  KITAMURA YUUKO ,  MIYAZAKI YOICHI ,  MITA KATSUYOSHI ,  ASANO TETSUYA ,  MATSUI AKIHIRO ,  MATSUTOMI TAEKO ,  ITO KOJI

IPC: G06F17/30

Abstract: PROBLEM TO BE SOLVED: To provide a similar sentence retrieval program for allowing a user to accurately and flexibly retrieve a similar sentence based on the position and context of a word in a sentence inputted by the user without taking account of a keyword.
SOLUTION: The computer program for retrieving a sentence similar to an inputted sentence, includes the following steps: of morphologically analyzing the inputted sentence to determine clauses, and analyzing modification for each of the clauses (S230, S240), arranging the clauses in appearance order, and if a clause having no verb or modified word appears, generating a compound word, which includes a verb/clause and grouping all the clauses appearing before the clause having no verb or modified word (S250), recording the compound word in association with the inputted sentence in a sentence database (S260), generating, when a new arbitrary original sentence is inputted, a compound word, and based on the compound word obtained for the original sentence, retrieving a sentence including the compound word from the sentence database.
COPYRIGHT: (C)2008,JPO&INPIT

Abstract translation: 要解决的问题：提供一种类似的句子检索程序，用于允许用户基于用户输入的句子中的单词的位置和上下文来准确和灵活地检索类似的句子，而不考虑关键字。 解决方案：用于检索与输入的句子相似的句子的计算机程序包括以下步骤：对形式上分析输入的句子以确定条款，并分析每个条款的修改（S230，S240），安排条款 并且如果出现没有动词或修饰词的子句，则生成包含动词/子句的复合词，并将出现在没有动词或修饰词的子句之前的所有子句分组（S250），记录复合词 与句子数据库中的输入句子相关联（S260），当输入新的任意原始句子时，生成复合词，并且基于为原始句子获得的复合词，从 句子数据库。 版权所有（C）2008，JPO＆INPIT

公开(公告)号：JP2013255485A

公开(公告)日：2013-12-26

申请号：JP2013092295

申请日：2013-04-25

Applicant: Shizuoka Prefecture ,  静岡県

Inventor： NAKAO KANAKO ,  MOCHIZUKI TORU ,  HATAKEYAMA KEIICHI ,  YAMAGUCHI KEN

IPC: C12N15/09 ,  C07K14/705 ,  C12Q1/68 ,  G01N33/15 ,  G01N33/50 ,  G01N33/574

Abstract: PROBLEM TO BE SOLVED: To provide a method for determining presence or absence of medullary thyroid cancer, which can specifically detect medullary thyroid cancer.SOLUTION: A method for determining presence or absence of medullary thyroid cancer uses a method having a process (a) for detecting expression of a splicing variant of CEACAM4 gene such as a cDNA composed of a specific base sequence in a sample for determination or the splicing variant such as a protein composed of an amino acid sequence encoded by the base sequence, etc., and a process (b) for evaluating that possibility of a sample donor for determination having medullary thyroid cancer is high when the expression of the splicing variant of CEACAM4 gene or a protein encoded by the splicing variant is detected in the process (a).

Abstract translation: 要解决的问题：提供一种确定髓质甲状腺癌的存在或不存在的方法，其可以特异性检测甲状腺髓样癌。解决方案：确定甲状腺髓样癌的存在或不存在的方法使用方法（a）用于 检测CEACAM4基因的剪接变体的表达，例如由用于测定的样品中的特异性碱基序列组成的cDNA或剪接变体如由碱基序列编码的氨基酸序列组成的蛋白质等的表达，以及方法 （b）为了评价当在（a）中检测到CEACAM4基因的剪接变体或由拼接变体编码的蛋白质的表达时，用于确定具有髓样甲状腺癌的样品供体的可能性很高。

公开(公告)号：JP2010211413A

公开(公告)日：2010-09-24

申请号：JP2009055622

申请日：2009-03-09

Applicant: Fujifilm Corp ,  Shizuoka Prefecture ,  富士フイルム株式会社 ,  静岡県

Inventor： HISANAGA TAKAHARU ,  OSAWA SATORU ,  FURUKAWA TAKAYOSHI ,  ENDO MASAHIRO ,  AKIMARU MASAHIRO ,  YAMAGUCHI KEN

IPC: G06F17/30 ,  A61B5/00 ,  G06Q50/22 ,  G06Q50/24 ,  G06T1/00

CPC classification number: G06T7/33 ,  G06F19/321 ,  G06T2207/30004 ,  G16H50/70

Abstract: PROBLEM TO BE SOLVED: To register a case image so that the deviation of featured values can be prevented from being generated in a case image included in the database of a similar image retrieval system for image diagnosis. SOLUTION: Since the registration of the case images to the database is controlled according to the degree of similarity of featured values, it is possible to reduce such possibility that many similar case images appear as retrieval results, and that similar retrieval results disturbing the diagnosis of a person to be diagnosed are shown. COPYRIGHT: (C)2010,JPO&INPIT

Abstract translation: 要解决的问题：为了注册病例图像，使得可以防止在包括在用于图像诊断的类似图像检索系统的数据库中的病例图像中产生特征值的偏差。

解决方案：由于根据特征值的相似度来控制病例图像到数据库的注册，可以减少许多类似病例图像作为检索结果出现的可能性，并且类似的检索结果令人不安 显示诊断患者的诊断。 版权所有（C）2010，JPO＆INPIT