Abstract:
Disclosed herein are primers and probes related to the detection of Neisseria gonorrhoeae via nucleic acid amplification testing (NAAT), for example to amplify and determine the presence of N. gonorrhoeae nucleic acids present in test samples. Specifically the present disclosure describes primers and probes that bind to the small subunit rRNA (cytosine (967)-C(5))-methyltransferase or rsmB gene of N. gonorrhoeae for detection via loop mediated isothermal amplification (LAMP) and molecular beacon hybridization.
Abstract:
Disclosed herein are methods and devices for rapid assessment of whether a microorganism present in a sample is susceptible or resistant to a treatment.
Abstract:
Disclosed herein are methods and compositions for detecting amplicon generated using loop-mediated amplification (LAMP). In particular, the invention relates to compositions comprising molecular beacons and/or LAMP primers and methods for generating and detecting LAMP amplicons. In particular, molecular beacons that bind to novel regions of a LAMP amplicon, and methods of using these probes, are provided.
Abstract:
The invention provides methods and compositions for the detection of Chlamydia trachomatis in a test sample. Its presence or absence in the sample is determined by nucleic acid based testing methods using primers and/or probes and or molecular beacons that bind to the 16S or 23S ribosomal genes or gene transcripts.
Abstract:
The present invention relates to fluidic systems for controlling one or more fluids or reagents. These systems can be used in combination with one or more devices for assaying, processing, or storing samples. In particular, the systems and related methods can allow for controlled pressure and actuation of fluids.
Abstract:
Disclosed herein are methods and devices for rapid assessment of whether a microorganism present in a sample is susceptible or resistant to a treatment.
Abstract:
The present invention relates to fluidic systems for controlling one or more fluids or reagents. These systems can be used in combination with one or more devices for assaying, processing, or storing samples. In particular, the systems and related methods can allow for controlled pressure and actuation of fluids.