公开(公告)号：CA1128064A

公开(公告)日：1982-07-20

申请号：CA347527

申请日：1980-03-12

Applicant: SNIA VISCOSA

Inventor： ROSSI PIETRO P ,  DE GAETANO MARIO

IPC: C07C227/06 ,  C07C67/00 ,  C07C227/00 ,  C07C227/08 ,  C07C227/18 ,  C07C229/08 ,  C07C101/04

Abstract: A process for continuous or batch preparation of an .omega.-amino-acid is described, comprising the imination of an unsaturated aldehyde acid, the catalytic reduction in a single hydrogenation step of the imine of the ethylenically unsaturated straight chain .omega.-aldehyde acid in the presence of ammonia and an alkaline metal hydroxide whereby the alkaline salt of the imine is obtained, and the acidification of the alkaline salt of the .omega.-amino acid. The imine of formyl alkenoic acid is prepared at most at room temperature adding the acid to an ammonia solution of above 10%, then adding NaOH solution to the ammonia solution The reductive imination is effectuated in two steps, first at 100-150.degree.C and the second at 150-180.degree.C under a 20-70 Ate pressure in the presence of a nickel catalyst. High yield and only few by-products are obtained.

公开(公告)号：DE3039321A1

公开(公告)日：1982-05-19

申请号：DE3039321

申请日：1980-10-17

Applicant: SNIA VISCOSA

Inventor： DE GAETANO MARIO ,  CANAVESI LUIGI

IPC: C11C1/08 ,  C07C101/04 ,  C07C99/12

Abstract: A process for recovering omega-amino-dodecanoic acid by separating the by-products from the crude acid that comprises, in the sequence indicated (a) treating the crude acid in the presence of water with an acid (A) in such an amount as to obtain an acid (A)/amino acid molar ratio comprised of between 2:1 and 1:1, the amount of water being such as to dissolve at least part of the salt obtained and not to dissolve at least part of the by-products, (b) separating the phases into one containing most of the salt and another containing most of the by-products, (c) decomposing the salt by treatment with an organic or inorganic base (B) and isolating the amino acid in the free state.