公开(公告)号：WO2014049055A3

公开(公告)日：2014-12-24

申请号：PCT/EP2013070070

申请日：2013-09-26

Applicant: SOFRADIM PRODUCTION

Inventor： LADET SÉBASTIEN ,  PROST NICOLAS

IPC: C08J9/28 ,  A61L27/20 ,  A61L27/56 ,  A61L31/04 ,  A61L31/14 ,  C08J5/18

CPC classification number: C08J9/28 ,  A61L27/20 ,  A61L31/042 ,  A61L31/146 ,  A61L2400/18 ,  C08J5/18 ,  C08J2201/048 ,  C08J2207/10 ,  C08J2305/04 ,  C08J2305/08 ,  C08L5/04 ,  C08L5/08

Abstract: The present invention relates to a process for preparing a porous layer of biocompatible polymer, having a uniform density and porosity, comprising the following steps: - a) a quantity Qp of solution of the said polymer, having a viscosity Vp, is poured into a mould in order to form a first sublayer, the surface of the first sublayer being left to the open air; - b) a quantity Qs of solvent, having a viscosity Vs, lower than Vp, is spread uniformly over the surface of the first sublayer so as to form a second sublayer; - c) the first and second sublayers are subjected to a step of lyophilisation, in which the said polymer is a polysaccharide chosen from hyaluronic acid, alginic acid and chitosan, salts thereof and mixtures thereof.

Abstract translation: 本发明涉及制备具有均匀密度和孔隙率的生物相容性聚合物多孔层的方法，包括以下步骤：a）将具有粘度Vp的所述聚合物溶液的量Qp倒入 模具以形成第一子层，第一子层的表面留在露天; b）具有低于Vp的粘度Vs的溶剂量Qs均匀地扩散到第一子层的表面上以形成第二子层; c）第一和第二子层进行冻干的步骤，其中所述聚合物是选自透明质酸，藻酸和壳聚糖的多糖，其盐及其混合物。

公开(公告)号：AU2016273944A1

公开(公告)日：2017-08-10

申请号：AU2016273944

申请日：2016-12-15

Applicant: SOFRADIM PRODUCTION

Inventor： FRANCOIS SEBASTIEN ,  THERIN MICHEL ,  PROST NICOLAS

IPC: A61F2/02

Abstract: PROSTHESIS FOR HERNIA REPAIR A prosthesis (1) for treating a hernia defect in the abdominal wall comprising at least one reinforcement layer (2), comprising a biocompatible porous material, said reinforcement layer including a first surface (2a) intended to face the abdominal wall and a second surface (2b) opposite said first surface, said reinforcement layer being delimited by an outer edge (2c); at least one first barrier layer (3), comprising a biocompatible anti-adhesion material, said first barrier layer including a first surface (3a) and a second surface (3b) opposite said first surface of the first barrier layer, the first surface of the first barrier layer covering substantially at least a central part of the area of the second surface of said reinforcement layer, the second surface of said first barrier layer being intended to face the abdominal cavity, said first barrier layer being delimited by an outer edge (3c); and at least one second barrier layer, said second barrier layer being shaped and dimensioned so as to cover at least the part of the area of the second surface of said reinforcement layer that is not covered by the first barrier layer, said second barrier layer comprising one or more flap members (4, 9, 14), each flap member being formed of a piece of sheet of biocompatible anti-adhesion material, and having at least an outer edge (5a, 10a) attached to the second surface of the reinforcement layer and a free inner edge (5b, 10b, 14b). r2a c 2 2c 1 s~a 3 3c >Fig. 1 4a /$\ 5b Y

公开(公告)号：FR3017537B1

公开(公告)日：2016-03-25

申请号：FR1451306

申请日：2014-02-19

Applicant: SOFRADIM PRODUCTION

Inventor： FRANCOIS SEBASTIEN ,  PROST NICOLAS ,  MONTANARI SUZELEI

IPC: A61L31/12 ,  A61L27/34 ,  A61L27/40 ,  A61L31/04

公开(公告)号：FR2985171A1

公开(公告)日：2013-07-05

申请号：FR1162536

申请日：2011-12-29

Applicant: SOFRADIM PRODUCTION

Inventor： LADET SEBASTIEN ,  FRANCOIS SEBASTIEN ,  PROST NICOLAS

IPC: A61F2/02

Abstract: Prothèse (1) comprenant une pièce (2) en matériau biocompatible, ladite pièce présentant une forme géométrique globalement plane définissant deux faces opposées, un centre, une longueur et une largeur de ladite pièce, caractérisée en ce que ladite pièce est munie sur une (2a) de ses faces d'un moyen de marquage unique (3) agencé pour désigner à la fois le centre (C) de la pièce et la direction longitudinale de ladite pièce.

公开(公告)号：CA2931791A1

公开(公告)日：2016-12-19

申请号：CA2931791

申请日：2016-05-31

Applicant: SOFRADIM PRODUCTION ,  COVIDIEN LP

Inventor： LECUIVRE JULIE ,  PROST NICOLAS ,  PRESCOTT MATTHEW ,  MAIORINO NICHOLAS ,  CORSO THOMAS

IPC: A61F2/10

Abstract: The present invention relates to a synthetic prosthesis for tissue reinforcement comprising : - a porous knit made from a monofilament of a synthetic biocompatible material, said knit defining two opposite faces, a first face and a second face, - a synthetic non porous biodegradable film comprising at least a copolymer of at least .epsilon.-caprolactone, said film covering at least part of said first face, - a synthetic biodegradable binder bonding said film to said first face, said binder comprising at least a polymer of .epsilon.-caprolactone, wherein said second face of said porous knit is left open to cell colonization. The invention also relates to a method for forming such a prosthesis.

公开(公告)号：CA2858002C

公开(公告)日：2019-09-03

申请号：CA2858002

申请日：2012-12-27

Applicant: SOFRADIM PRODUCTION

Inventor： LADET SEBASTIEN ,  FRANCOIS SEBASTIEN ,  PROST NICOLAS

IPC: A61F2/00

Abstract: Prosthesis (1) comprising a patch (2) made of biocompatible material, said patch having a generally plane geometric shape that defines two opposite faces, a centre, a length and a width of said patch, characterized in that said patch is provided,on one (2a) of its faces,with a single marking means (3) designed to indicate both the centre (C) of the patch and also the longitudinal direction of said patch.

公开(公告)号：AU2012360856B2

公开(公告)日：2017-02-23

申请号：AU2012360856

申请日：2012-12-27

Applicant: SOFRADIM PRODUCTION

Inventor： LADET SEBASTIEN ,  FRANCOIS SEBASTIEN ,  PROST NICOLAS

IPC: A61F2/00

Abstract: Prosthesis (1) comprising a patch (2) made of biocompatible material, said patch having a generally plane geometric shape that defines two opposite faces, a centre, a length and a width of said patch, characterized in that said patch is provided,on one (2a) of its faces,with a single marking means (3) designed to indicate both the centre (C) of the patch and also the longitudinal direction of said patch.

公开(公告)号：FR2995904B1

公开(公告)日：2015-09-18

申请号：FR1259084

申请日：2012-09-27

Applicant: SOFRADIM PRODUCTION

Inventor： LADET SEBASTIEN ,  PROST NICOLAS

IPC: C08J9/28 ,  A61F2/02 ,  A61L27/20 ,  A61L27/56

公开(公告)号：FR3017537A1

公开(公告)日：2015-08-21

申请号：FR1451306

申请日：2014-02-19

Applicant: SOFRADIM PRODUCTION

Inventor： FRANCOIS SEBASTIEN ,  PROST NICOLAS ,  MONTANARI SUZELEI

IPC: A61L31/12 ,  A61L27/34 ,  A61L27/40 ,  A61L31/04

公开(公告)号：AU2012360856A1

公开(公告)日：2014-06-05

申请号：AU2012360856

申请日：2012-12-27

Applicant: SOFRADIM PRODUCTION

Inventor： LADET SEBASTIEN ,  FRANCOIS SEBASTIEN ,  PROST NICOLAS

IPC: A61F2/00

Abstract: Prosthesis (1) comprising a patch (2) made of biocompatible material, said patch having a generally plane geometric shape that defines two opposite faces, a centre, a length and a width of said patch, characterized in that said patch is provided,on one (2a) of its faces,with a single marking means (3) designed to indicate both the centre (C) of the patch and also the longitudinal direction of said patch.