-
公开(公告)号：ES2324741T3
公开(公告)日：2009-08-13
申请号：ES07712041
申请日：2007-01-16
Applicant: SOLVAY PHARM GMBH
Inventor： MESSINGER JOSEF , THOLE HEINRICH-HUBERT , RASCHE HEINZ-HELMER , SCHMIDT MICHAEL , HAKALA JUHA
Abstract: Uso de un microorganismo bacteriano de la especie Amycolatopsis mediterranei para la transformación de un compuesto 9 beta,10alfa-esteroide de Fórmula general (I) ** ver fórmula** en la que R1 y R4 juntos forman un oxígeno, o R4 es un grupo beta-acetilo y R1 se selecciona del grupo que consiste en hidrógeno, -OH, -O-alquilo(C1-C4), y -O- CO-alquilo(C1-C4), y R2 y R3 son ambos hidrógeno o juntos forman un grupo metileno, en su análogo de 11beta-hidroxilo correspondiente.
-
Patent Agency Ranking
公开(公告)号：DE602007000858D1
公开(公告)日：2009-05-20
申请号：DE602007000858
申请日：2007-01-16
Applicant: SOLVAY PHARM GMBH
Inventor： MESSINGER JOSEF , THOLE HEINRICH-HUBERT , RASCHE HEINZ-HELMER , SCHMIDT MICHAEL , HAKALA JUHA
Abstract: The invention relates to the use of bacterial strains of the species Amycolatopsis mediterranei for the microbial transformation of 9ß,10a-steroids of general Formula (I) to their corresponding 11ß-hydroxyl analogues, as well as to specific strains of that species. In addition, the present invention relates to the process of transforming 9ß,10a-steroids to their corresponding 11ß-hydroxyl derivatives using bacterials strains of the species Amycolatopsis mediterranei, and to the subsequent isolation of the 11ß-hydroxyl derivatives from the bacterial culture medium. The resultant 11ß-hydroxylated products are useful intermediates for the preparation of novel steroidal compounds with 9ß,10a-confirmation carrying different kind of substituents in the 11ß-position.
-
公开(公告)号：PL1976997T3
公开(公告)日：2009-09-30
申请号：PL07712041
申请日：2007-01-16
Applicant: SOLVAY PHARM GMBH
Inventor： MESSINGER JOSEF , THOLE HEINRICH-HUBERT , RASCHE HEINZ-HELMER , SCHMIDT MICHAEL , HAKALA JUHA
-
公开(公告)号：AT427998T
公开(公告)日：2009-04-15
申请号：AT07712041
申请日：2007-01-16
Applicant: SOLVAY PHARM GMBH
Inventor： MESSINGER JOSEF , THOLE HEINRICH-HUBERT , RASCHE HEINZ-HELMER , SCHMIDT MICHAEL , HAKALA JUHA
Abstract: The invention relates to the use of bacterial strains of the species Amycolatopsis mediterranei for the microbial transformation of 9ß,10a-steroids of general Formula (I) to their corresponding 11ß-hydroxyl analogues, as well as to specific strains of that species. In addition, the present invention relates to the process of transforming 9ß,10a-steroids to their corresponding 11ß-hydroxyl derivatives using bacterials strains of the species Amycolatopsis mediterranei, and to the subsequent isolation of the 11ß-hydroxyl derivatives from the bacterial culture medium. The resultant 11ß-hydroxylated products are useful intermediates for the preparation of novel steroidal compounds with 9ß,10a-confirmation carrying different kind of substituents in the 11ß-position.
-
公开(公告)号：CA2637731A1
公开(公告)日：2007-07-26
申请号：CA2637731
申请日：2007-01-16
Applicant: SOLVAY PHARM GMBH
Inventor： MESSINGER JOSEF , THOLE HEINRICH-HUBERT , RASCHE HEINZ-HELMER , SCHMIDT MICHAEL , HAKALA JUHA
Abstract: The invention relates to the use of bacterial strains of the species Amycolatopsis mediterranei for the microbial transformation of 9ß,10a-steroids of general Formula (I) to their corresponding 11ß-hydroxyl analogues, as well as to specific strains of that species. In addition, the present invention relates to the process of transforming 9ß,10a-steroids to their corresponding 11ß-hydroxyl derivatives using bacterials strains of the species Amycolatopsis mediterranei, and to the subsequent isolation of the 11ß-hydroxyl derivatives from the bacterial culture medium. The resultant 11ß-hydroxylated products are useful intermediates for the preparation of novel steroidal compounds with 9ß,10a-confirmation carrying different kind of substituents in the 11ß-position.
-
公开(公告)号：AU2007206959A1
公开(公告)日：2007-07-26
申请号：AU2007206959
申请日：2007-01-16
Applicant: SOLVAY PHARM GMBH
Inventor： HAKALA JUHA , MESSINGER JOSEF , THOLE HEINRICH-HUBERT , RASCHE HEINZ-HELMER , SCHMIDT MICHAEL
Abstract: The invention relates to the use of bacterial strains of the species Amycolatopsis mediterranei for the microbial transformation of 9ß,10a-steroids of general Formula (I) to their corresponding 11ß-hydroxyl analogues, as well as to specific strains of that species. In addition, the present invention relates to the process of transforming 9ß,10a-steroids to their corresponding 11ß-hydroxyl derivatives using bacterials strains of the species Amycolatopsis mediterranei, and to the subsequent isolation of the 11ß-hydroxyl derivatives from the bacterial culture medium. The resultant 11ß-hydroxylated products are useful intermediates for the preparation of novel steroidal compounds with 9ß,10a-confirmation carrying different kind of substituents in the 11ß-position.
-
-
-
-
-
Search Results
6
records
(took 0.022 seconds)
