Compressed tablets containing compacted starch as binder-disintegrant ingredient
    2.
    发明授权
    Compressed tablets containing compacted starch as binder-disintegrant ingredient 失效
    含有压实淀粉的压片包含消毒剂成分

    公开(公告)号:US3622677A

    公开(公告)日:1971-11-23

    申请号:US3622677D

    申请日:1969-07-07

    CPC classification number: A61J3/10 A61K9/2059 Y10S514/96

    Abstract: A directly compressed tablet containing as a binder-disintegrant ingredient, a partially cold-water soluble, cold-water swelling starch material derived from compacted granular starch, e.g. compacted native corn starch. The compacted granular starch is a superficially dry, free-flowing powder in which the starch is in the form of a mixture of birefringent granules and nonbirefringent fragments of granules, in which some aggregates of granules and fragments are present. The use of the starch binder-disintegrant ingredient allows active ingredients, e.g. pharmaceuticals, to be tabletted by direct compression.

    4.
    发明专利
    未知

    公开(公告)号:MX5120E

    公开(公告)日:1983-03-24

    申请号:MX557577

    申请日:1977-03-24

    Inventor: VERBANAC FRANK

    Abstract: The invention relates to starch acrylamides containing polymerizable pendant acrylamide groups. The hydrophilic or hydrophobic properties of the starch can be altered or modified by the acrylamide groups or the type of starch chain. The starch acrylamides can be homopolymerized or copolymerized with other ethylenically unsaturated monomers as well as other cross-linking reagents to provide water-resistant, clear, flexible coatings or shaped articles. The hydrophilic starch acrylamide hydrolyzates herein readily disperse into water at a high solids level to provide low-viscosity pastes which may be used as a vehicle to prepare flexible, water-insoluble starch-based coatings. The starch acrylamides may be prepared by etherifying a starch with N-methylol acrylamides in the presence of an acid catalyst and a polymerization inhibitor.

    ACRYLAMIDE-FUNCTIONAL CELLULOSE ESTER OR ETHER PRODUCTS

    公开(公告)号:CA1234566A

    公开(公告)日:1988-03-29

    申请号:CA466977

    申请日:1984-11-02

    Inventor: VERBANAC FRANK

    Abstract: The invention provides an improved cellulosic ester or ether product with a degree of ester or ether substitution of between 2 . 0 and about 2 . 9 which is derivatized or further reacted by reaction with an acrylamide reactant to provide pendant acrylamide functionality or substituents at a degree of substitution (D.S.) of at least about 0.05 (preferably from about 0.05 to about 0.5) and to thereby provide a polymerizable organic solvent-soluble product which is insoluble in water and copolymerizable with vinyl monomers. The product is conveniently prepared by reacting said cellulose ether or ester derivative with a catalyst and the acrylamide reactant at a pH of from between about 4.2 and about 4.5. The reaction is carried out at a temperature between 80.degree.C. and 120.degree.C. for from one-half to three hours, while removing the water of reaction. The resulting acrylamide functionality-containing cellulose ester or ether product typically contains unreacted, residual hydroxyl groups in an amount corresponding to a hydroxyl D.S. of from about 0.05 to about 0.95.

    STARCH ACRYLAMIDES AND THE METHOD FOR PREPARING THE SAME

    公开(公告)号:CA1091659A

    公开(公告)日:1980-12-16

    申请号:CA344748

    申请日:1980-01-30

    Inventor: VERBANAC FRANK

    Abstract: A polymerized starch acrylamide composition having recurring and interpolymerized starch acrylamide units and a method for preparing same by polymerizing an ethylenically unsaturated starch derivative in the presence of a polymerization initiator. The starch acrylamide has a starch chain with appendant acrylamide groups contiguously attached to the chain. The polymerized compositions provide water-resistant, clear, flexible coatings or shaped articles.

    STARCH ACRYLAMIDES AND THE METHOD FOR PREPARING THE SAME

    公开(公告)号:CA1085389A

    公开(公告)日:1980-09-09

    申请号:CA274113

    申请日:1977-03-16

    Inventor: VERBANAC FRANK

    Abstract: The invention relates to starch acrylamides containing polymerizable pendant acrylamide groups. The hydrophilic or hydrophobic properties of the starch can be altered or modified by the acrylamide groups or the type of starch chain. The starch acrylamides can be homopolymerized or copolymerized with other ethylenically unsaturated monomers as well as other cross-linking reagents to provide water-resistant, clear, flexible coatings or shaped articles. The hydrophilic starch acrylamide hydrolyzates herein readily disperse into water at a high solids level to provide low-viscosity pastes which may be used as a vehicle to prepare flexible, water-insoluble starch-based coatings. The starch acrylamides may be prepared by etherifying a starch with N-methylol acrylamides in the presence of an acid catalyst and a polymerization inhibitor.

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