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公开(公告)号：WO2013092701A1
公开(公告)日：2013-06-27
申请号：PCT/EP2012/076135
申请日：2012-12-19
Applicant: STAMFORD DEVICES LIMITED
Inventor： HOGAN, Brendan , BUTAN, Daniela , CLIFFORD, Seamus , POMEROY, Michael , SOUTHERN, Mark , SHEIL, David
CPC classification number: B05B17/0646 , B05B17/0669 , C22C5/04 , C25D1/10 , C25D3/567
Abstract: An aperture plate is formed from a palladium nickel alloy comprising about 89% palladium and about 11% nickel. There is a generally fine substantially equiaxed grain microstructure throughout the thickness of the aperture plate. The average grain width (W) is in the range of from 0.2 μm to 5.0 μm, in some cases from 0.2 μm to 2.0 μm. Because the grain structure is equiaxed (L/W =1) the grain length (L) is the same as the grain width. The improved aperture plate extends the life of nebulisers, eliminates the risk of premature and unpredictable failure of a nebuliser in service, eliminates the risk of product returns from hospitals and patients, and eliminates the possible risk of fragments of the aperture plate breaking free from the nebulizer.
Abstract translation: 孔板由包含约89％钯和约11％镍的钯镍合金形成。 在孔板的整个厚度上存在通常细的基本上等轴晶粒微观结构。 平均晶粒宽度（W）在0.2μm至5.0μm的范围内，在一些情况下为0.2μm至2.0μm。 由于晶粒结构为等轴（L / W = 1），晶粒长度（L）与晶粒宽度相同。 改进的孔板延长了雾化器的寿命，消除了雾化器在使用过程中过早和不可预测的故障的风险，消除了医院和患者的产品返回风险，并消除了孔板破碎的可能性， 喷雾器。
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公开(公告)号：WO2016198667A1
公开(公告)日：2016-12-15
申请号：PCT/EP2016/063395
申请日：2016-06-10
Applicant: STAMFORD DEVICES LIMITED
Inventor： MACLOUGHLIN, Ronan , DUFFY, Conor , HOGAN, Brendan , KELLY, Patrick Martin
IPC: B05B17/00
CPC classification number: B05B17/0646
Abstract: A method for aerosolising a liquid comprises the steps of:- providing an aperture plate having at least 100 outlet holes per mm; delivering liquid to the aperture plate; and vibrating the aperture plate to produce an aerosol. The viscosity of the liquid is in the range of from 1 tol5 cP and the surface tension of the liquid is in the range of from 72 to 0.5 mN/m. The output rate of the generated aerosol is greater than 0.01 mL/min.
Abstract translation: 一种用于气溶胶化的方法包括以下步骤： - 提供孔径，每孔具有至少100个出口孔; 将液体输送到孔板; 并振动孔板产生气溶胶。 液体的粘度在1至15cP的范围内，液体的表面张力在72至0.5mN / m的范围内。 产生气溶胶的产出率大于0.01 mL / min。
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公开(公告)号：WO2013186031A3
公开(公告)日：2013-12-19
申请号：PCT/EP2013/060803
申请日：2013-05-24
Applicant: STAMFORD DEVICES LIMITED
Inventor： HOGAN, Brendan
Abstract: A photo-resist (21) is applied in a pattern of vertical columns having the dimensions of holes or pores of the aperture plate to be produced. This mask pattern provides the apertures which define the aerosol particle size, having up to 2500 holes per square mm. There is electro-deposition of metal (22) into the spaces around the columns (21). There is further application of a second photo-resist mask (25) of much larger (wider and taller) columns, encompassing the area of a number of first columns (21). The hole diameter in the second plating layer is chosen according to a desired flow rate.
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公开(公告)号：WO2012046220A1
公开(公告)日：2012-04-12
申请号：PCT/IE2011/000054
申请日：2011-10-03
Applicant: STAMFORD DEVICES LIMITED , HOGAN, Brendan , HYLAND, Kieran , REDMOND, Anthony
Inventor： HOGAN, Brendan , HYLAND, Kieran , REDMOND, Anthony
CPC classification number: B05B17/0646 , A61M11/001 , A61M11/005 , A61M15/0085
Abstract: An aerosol generator (100) has a vibratable plate (1) with apertures therein and an annular piezo (2) which causes movement of the vibratable plate (1). An annular support member (3) supports the piezo (2) and the vibratable plate (1). A first electrical power conducting pin (10) engages directly with a first, top, surface of the piezo (2). A second electrical power conducting pin (11) indirectly conducts electrical power to a second surface of the piezo (2), by contacting an extension tab (103) of the support member (20), also on its top side. There is a film of cured epoxy adhesive on the tab (103), providing excellent gripping force between the pin (11) and the support (3). The aerosol generator (100) avoids need for soldered joints for electrical contact, and the pins are conveniently mounted parallel to each on the on the same lateral and top side of the piezo and support member. The pins may have multi-point tips (50) for particularly effective.
Abstract translation: 气溶胶发生器（100）具有其中具有孔的可振动板（1）和引起可振动板（1）移动的环形压电体（2）。 环形支撑构件（3）支撑压电体（2）和可振动板（1）。 第一电力导电销（10）与压电体（2）的第一顶表面直接接合。 第二电力导电销（11）通过在支撑构件（20）的顶侧上接触支撑构件（20）的延伸片（103）来间接地将电力传导到压电体（2）的第二表面。 在片（103）上存在固化的环氧树脂粘合剂膜，在销（11）和支撑（3）之间提供优异的夹持力。 气溶胶发生器（100）避免了用于电接触的焊接接头的需要，并且销被方便地平行地安装在压电和支撑构件的同一横向和顶侧上。 销可以具有特别有效的多点尖端（50）。
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公开(公告)号：WO2015177311A1
公开(公告)日：2015-11-26
申请号：PCT/EP2015/061329
申请日：2015-05-21
Applicant: STAMFORD DEVICES LIMITED
Inventor： HOGAN, Brendan , XU, Hong
CPC classification number: B05B1/02 , A61M11/005 , A61M15/0085 , A61M2207/00 , B05B17/0638 , B05B17/0653 , C25D1/08 , C25D7/04
Abstract: An aperture plate is manufactured by plating metal around a mask of resist columns (2) having a desired size, pitch, and profile, which yields a wafer about 60μιη thickness. This is approximately the full desired target aperture plate thickness. The plating is continued so that the metal (3) overlies the top surfaces of the columns until the desired apertures (4) are achieved. This needs only one masking/plating cycle to achieve the desired plate thickness. Also, the plate has passageways (24) formed beneath the apertures (32), formed as an integral part of the method, by mask material removal. These are suitable for entrainment of aerosolized droplets exiting the apertures (32).
Abstract translation: 通过在具有期望的尺寸，间距和轮廓的抗蚀剂柱（2）的掩模上镀覆金属来制造孔板，其产生约60μI厚度的晶片。 这大约是完全期望的目标孔板厚度。 继续进行电镀，使得金属（3）覆盖在柱的顶表面上，直到达到所需的孔（4）。 这只需要一个掩模/电镀周期来实现所需的板厚度。 此外，板具有形成在孔（32）下方的通道（24），其形成为该方法的组成部分，通过掩模材料去除。 这些适合于夹带离开孔（32）的雾化液滴。
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Patent Agency Ranking
公开(公告)号：EP3797874A1
公开(公告)日：2021-03-31
申请号：EP20207577.6
申请日：2011-10-03
Applicant: Stamford Devices Limited
Inventor： HOGAN, Brendan , HYLAND, Kieran , REDMOND, Anthony
Abstract: An aerosol generator (100) has a vibratable plate (1) with apertures therein and an annular piezo (2) which causes movement of the vibratable plate (1). An annular support member (3) supports the piezo (2) and the vibratable plate (1). A first electrical power conducting pin (10) engages directly with a first, top, surface of the piezo (2). A second electrical power conducting pin (11) indirectly conducts electrical power to a second surface of the piezo (2), by contacting an extension tab (103) of the support member (20), also on its top side. There is a film of cured epoxy adhesive on the tab (103), providing excellent gripping force between the pin (11) and the support (3). The aerosol generator (100) avoids need for soldered joints for electrical contact, and the pins are conveniently mounted parallel to each on the on the same lateral and top side of the piezo and support member. The pins may have multipoint tips (50) for particularly effective electrical contact.
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公开(公告)号：EP3476982A1
公开(公告)日：2019-05-01
申请号：EP18208663.7
申请日：2013-05-24
Applicant: Stamford Devices Limited
Inventor： HOGAN, Brendan
Abstract: A photo-resist (21) is applied in a pattern of vertical columns having the dimensions of holes or pores of the aperture plate to be produced. This mask pattern provides the apertures which define the aerosol particle size, having up to 2500 holes per square mm. There is electro-deposition of metal (22) into the spaces around the columns (21). There is further application of a second photo-resist mask (25) of much larger (wider and taller) columns, encompassing the area of a number of first columns (2)1. The hole diameter in the second plating layer is chosen according to a desired flow rate.
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公开(公告)号：EP3308865A1
公开(公告)日：2018-04-18
申请号：EP17197100.5
申请日：2011-10-03
Applicant: Stamford Devices Limited
Inventor： HOGAN, Brendan , HYLAND, Kieran , REDMOND, Anthony
CPC classification number: B05B17/0646 , A61M11/001 , A61M11/005 , A61M15/0085
Abstract: An aerosol generator (100) has a vibratable plate (1) with apertures therein and an annular piezo (2) which causes movement of the vibratable plate (1). An annular support member (3) supports the piezo (2) and the vibratable plate (1). A first electrical power conducting pin (10) engages directly with a first, top, surface of the piezo (2). A second electrical power conducting pin (11) indirectly conducts electrical power to a second surface of the piezo (2), by contacting an extension tab (103) of the support member (20), also on its top side. There is a film of cured epoxy adhesive on the tab (103), providing excellent gripping force between the pin (11) and the support (3). The aerosol generator (100) avoids need for soldered joints for electrical contact, and the pins are conveniently mounted parallel to each on the on the same lateral and top side of the piezo and support member. The pins may have multipoint tips (50) for particularly effective electrical contact.
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公开(公告)号：EP3308864A1
公开(公告)日：2018-04-18
申请号：EP17197095.7
申请日：2011-10-03
Applicant: Stamford Devices Limited
Inventor： HOGAN, Brendan , HYLAND, Kieran , REDMOND, Anthony
CPC classification number: B05B17/0646 , A61M11/001 , A61M11/005 , A61M15/0085
Abstract: An aerosol generator (100) has a vibratable plate (1) with apertures therein and an annular piezo (2) which causes movement of the vibratable plate (1). An annular support member (3) supports the piezo (2) and the vibratable plate (1). A first electrical power conducting pin (10) engages directly with a first, top, surface of the piezo (2). A second electrical power conducting pin (11) indirectly conducts electrical power to a second surface of the piezo (2), by contacting an extension tab (103) of the support member (20), also on its top side. There is a film of cured epoxy adhesive on the tab (103), providing excellent gripping force between the pin (11) and the support (3). The aerosol generator (100) avoids need for soldered joints for electrical contact, and the pins are conveniently mounted parallel to each on the on the same lateral and top side of the piezo and support member. The pins may have multipoint tips (50) for particularly effective electrical contact.
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公开(公告)号：EP3146090B1
公开(公告)日：2018-03-28
申请号：EP15727907.6
申请日：2015-05-21
Applicant: STAMFORD DEVICES LIMITED
Inventor： HOGAN, Brendan , XU, Hong
CPC classification number: B05B1/02 , A61M11/005 , A61M15/0085 , A61M2207/00 , B05B17/0638 , B05B17/0653 , C25D1/08 , C25D7/04
Abstract: An aperture plate is manufactured by plating metal around a mask of resist columns having a desired size, pitch, and profile, which yields a wafer about 60 μm thickness. This is approximately the full desired target aperture plate thickness. The plating is continued so that the metal overlies the top surfaces of the columns until the desired apertures are achieved. This needs only one masking/plating cycle to achieve the desired plate thickness. Also, the plate has passageways formed beneath the apertures, formed as an integral part of the method, by mask material removal. These are suitable for entrainment of aerosolized droplets exiting the apertures.
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