公开(公告)号：AU2016215110A1

公开(公告)日：2017-09-21

申请号：AU2016215110

申请日：2016-02-05

Applicant: STC UNM ,  WILSON BRIDGET ,  WINTER STUART ,  ERASMUS MICHAEL ,  HOROWITZ MICHAEL

Inventor： WILSON BRIDGET S ,  WINTER STUART S ,  ERASMUS MICHAEL FRANK ,  HOROWITZ MICHAEL

IPC: A61K39/00 ,  A61P35/02

Abstract: This disclosure describes the identification of pre-B Cell Receptor (pre-BCR) antagonists and the use of pre-BCR antagonists as a targeted therapy. The compositions and methods generally involve a composition that includes a pre-B cell receptor (pre-BCR) antagonist and is engineered for expression as a T cell chimeric receptor. In some embodiments, the pre-BCR antagonists can include an anti-pre-BCR antibody.

公开(公告)号：HK1250146A1

公开(公告)日：2018-11-30

申请号：HK18109616

申请日：2018-07-25

Applicant: STC UNM

Inventor： WILSON BRIDGET S ,  WINTER STUART S ,  ERASMUS MICHAEL FRANK ,  HOROWITZ MICHAEL

IPC: A61K20060101 ,  A61P20060101