公开(公告)号：WO2017123651A1

公开(公告)日：2017-07-20

申请号：PCT/US2017/013042

申请日：2017-01-11

Applicant: STC. UNM ,  ZARKESH-HA, Payman ,  EDWARDS, Jeremy ,  SZAUTER, Paul

Inventor： ZARKESH-HA, Payman ,  EDWARDS, Jeremy ,  SZAUTER, Paul

IPC: C12Q1/68 ,  G01N27/414 ,  G01N33/543 ,  G01N27/447

CPC classification number: C12Q1/68 ,  C12Q1/6869 ,  G01N27/4146 ,  G01N27/447 ,  C12Q2565/607

Abstract: This disclosure describes, in one aspect, a method of electric-field-assisted nucleotide sequencing. Generally, the method includes performing an ion-sensitive nucleotide sequencing method, applying an electric field across the device while the nucleotide sequencing reactions are being performed so that ions released by the sequencing reactions are directed to contact with the ion-sensitive detector, and detecting at least a portion of the released ions in contact with the ion-sensitive detector.

Abstract translation: 本公开在一个方面描述了电场辅助核苷酸测序的方法。 通常，该方法包括执行离子敏感性核苷酸测序方法，在正在进行核苷酸测序反应的同时在设备上施加电场，使得由测序反应释放的离子指向与离子敏感检测器接触，并且检测 至少一部分释放的离子与离子敏感的检测器接触。

公开(公告)号：WO2018217823A1

公开(公告)日：2018-11-29

申请号：PCT/US2018/033981

申请日：2018-05-22

Applicant: STC. UNM

Inventor： BRUECK, Steven R. J. ,  ZARKESH-HA, Payman ,  NEUMANN, Alexander

IPC: G01J3/24 ,  G02B6/10

Abstract: Provided is a spectral sensor array, including: a planar waveguide on a substrate; a chirped input coupling grating, wherein the chirped input coupling grating comprises a transverse chirp to provide a spectrally selective coupling of incident light into the planar waveguide; an output coupling grating; and an array of photodetectors arranged to receive the light coupled out of the waveguide.

公开(公告)号：WO2017189124A1

公开(公告)日：2017-11-02

申请号：PCT/US2017/023424

申请日：2017-03-21

Applicant: STC. UNM

Inventor： KRISHNA, Sanjay ,  ZARKESH-HA, Payman ,  RAMIREZ, David, A. ,  KLEIN, Brianna ,  CAVALLO, Francesca ,  ZAMIRI, Seyedeh, Marziyeh ,  KAZEMI, Alireza ,  KADLEC, Clark

IPC: G01N27/414 ,  H01L31/04 ,  H01L31/18 ,  H01L29/772

CPC classification number: G01N27/414 ,  H01L27/1461 ,  H01L27/14612 ,  H01L29/20 ,  H01L31/0304 ,  H01L31/112 ,  H01L31/1136 ,  H01L31/184 ,  Y02E10/544

Abstract: A detector or sensor including a transistor having a sensor element that generates a current when exposed to a stimulus such as light or a chemical, in one implementation, the sensor element is positioned between a transistor gate and a transistor channel. When the sensor element is not being exposed to the stimulus, the transistor outputs a first voltage on a transistor drain contact when the transistor Inverts. When the sensor element is being exposed to the stimulus, the transistor outputs a second voltage on the transistor drain contact when the transistor inverts, where the second voltage is higher than the first voltage.

Abstract translation: 在一种实施方式中，包括具有传感器元件的晶体管的检测器或传感器在一种实施方式中在传感器元件暴露于诸如光或化学物质的刺激时产生电流，传感器元件位于晶体管栅极和 晶体管通道。 当传感器元件未暴露于刺激时，当晶体管Inverts时，晶体管在晶体管漏极触点上输出第一电压。 当传感器元件暴露于刺激时，当晶体管反相时，晶体管在晶体管漏极触点上输出第二电压，其中第二电压高于第一电压。