公开(公告)号：EP2498848A2

公开(公告)日：2012-09-19

申请号：EP10830835.4

申请日：2010-11-12

Applicant: STC.UNM

Inventor： SMYTH, Hugh, D.C. ,  SELVAM, Parthiban ,  TRUMAN, Charles, Randall

IPC: A61M15/00 ,  A61M11/02

CPC classification number: A61M15/0028 ,  A61M11/003 ,  A61M15/0031 ,  A61M15/0038 ,  A61M15/0086 ,  A61M2202/064 ,  A61M2205/0233 ,  A61M2206/16

Abstract: A dry powder inhaler including a housing defining a chamber for receiving a dose of powdered medicament, an inhalation port in fluid communication with the chamber, at least one airflow inlet providing fluid communication between the chamber and an exterior of the housing, and a flutter element in the chamber and associated with a dose of powdered medicament. The flutter element has a tensioned distal end proximate the at least one airflow inlet and a free proximal end opposite to the distal end and downstream of the inlet. The flutter element is configured to vibrate in response to airflow through the chamber and aerosolize the dose of powdered medicament.

公开(公告)号：EP2544825A2

公开(公告)日：2013-01-16

申请号：EP11754041.9

申请日：2011-03-09

Applicant: STC.UNM

Inventor： SELVAM, Parthiban ,  SMYTH, Hugh, D.C. ,  DONOVAN, Martin

IPC: B05B7/14 ,  B05B7/24 ,  B05B7/02 ,  B05B15/00

CPC classification number: B05B7/144 ,  A61M15/0028 ,  A61M15/0065 ,  A61M15/009 ,  A61M2202/064 ,  A61M2205/0233 ,  A61M2205/0238 ,  B05B12/36 ,  B05B13/0207

Abstract: A device for coating dry powder microparticles onto a surface may include a jet mill configured to mill dry powder particles into microparticles having a desired aerodynamic diameter and to deaggregate the microparticles, a feed hopper structured and arranged to feed dry powder particles to the jet mill, a surface configured to receive dry powder microparticles and an exit nozzle associated with the jet mill. The exit nozzle may be arranged to direct deaggregated micronized dry powder particles from the jet mill to the surface to be coated. The device may further include a holder structured and arranged to hold an item, wherein the item includes the surface. In some aspects of the device, the item may be a film.

公开(公告)号：WO2011112756A3

公开(公告)日：2011-09-15

申请号：PCT/US2011/027797

申请日：2011-03-09

Applicant: STC.UNM ,  SELVAM, Parthiban ,  SMYTH, Hugh, D.C. ,  DONOVAN, Martin

Inventor： SELVAM, Parthiban ,  SMYTH, Hugh, D.C. ,  DONOVAN, Martin

IPC: B05B7/14 ,  B05B7/24 ,  B05B7/02 ,  B05B15/00

Abstract: A device for coating dry powder microparticles onto a surfacemay include a jet mill configured to mill dry powder particles into microparticles having a desired aerodynamic diameter and to deaggregate the microparticles, a feed hopper structured and arranged to feed dry powder particles to the jet mill, a surface configured to receive dry powder microparticles and an exit nozzle associated with the jet mill. The exit nozzle may be arranged to direct deaggregated micronized dry powder particles from the jet mill to the surface to be coated. The device may further include a holder structured and arranged to hold an item, wherein the item includes the surface. In some aspects of the device, the item may be a film.

公开(公告)号：WO2011060334A2

公开(公告)日：2011-05-19

申请号：PCT/US2010/056628

申请日：2010-11-12

Applicant: STC.UNM ,  SMYTH, Hugh, D.C. ,  SELVAM, Parthiban ,  TRUMAN, Charles, Randall

Inventor： SMYTH, Hugh, D.C. ,  SELVAM, Parthiban ,  TRUMAN, Charles, Randall

CPC classification number: A61M15/0028 ,  A61M11/003 ,  A61M15/0031 ,  A61M15/0038 ,  A61M15/0086 ,  A61M2202/064 ,  A61M2205/0233 ,  A61M2206/16

Abstract: A dry powder inhaler including a housing defining a chamber for receiving a dose of powdered medicament, an inhalation port in fluid communication with the chamber, at least one airflow inlet providing fluid communication between the chamber and an exterior of the housing, and a flutter element in the chamber and associated with a dose of powdered medicament. The flutter element has a tensioned distal end proximate the at least one airflow inlet and a free proximal end opposite to the distal end and downstream of the inlet. The flutter element is configured to vibrate in response to airflow through the chamber and aerosolize the dose of powdered medicament.

Abstract translation: 一种干粉吸入器，包括限定用于接收一剂粉末状药剂的腔室的壳体，与腔室流体连通的吸入端口，至少一个气流入口，所述至少一个气流入口提供腔室与外部之间的流体连通 壳体中的颤动元件以及腔室中的颤动元件并且与一定剂量的粉状药剂相关联。 颤动元件具有靠近至少一个气流入口的张紧远端和与远端相对且在入口下游的自由近端。 颤振元件构造成响应于通过腔室的气流而振动并且雾化剂量的粉状药物。