公开(公告)号：EP3152788A1

公开(公告)日：2017-04-12

申请号：EP15807428.6

申请日：2015-06-09

Applicant: Stc.Unm

Inventor： BRUECK, Steven, R., J. ,  NEUMANN, Alexander ,  ZARKESH-HA, Payman

IPC: H01L33/58 ,  H01L33/48 ,  F21S2/00

CPC classification number: G01J1/06 ,  G01J1/44 ,  G01J3/0218 ,  G01J3/0259 ,  G01J3/18 ,  G01J3/1895 ,  G01J3/2803 ,  G01J2001/448 ,  G02B6/00 ,  G02B6/10 ,  G02B6/12004 ,  G02B6/122 ,  G02B6/124 ,  H01L27/1446 ,  H01L31/02019 ,  H01L31/02164 ,  H01L31/02327 ,  H01L31/103

Abstract: A 2-D sensor array includes a semiconductor substrate and a plurality of pixels disposed on the semiconductor substrate. Each pixel includes a coupling region and a junction region, and a slab waveguide structure disposed on the semiconductor substrate and extending from the coupling region to the region. The slab waveguide includes a confinement layer disposed between a first cladding layer and a second cladding layer. The first cladding and the second cladding each have a refractive index that is lower than a refractive index of the confinement layer. Each pixel also includes a coupling structure disposed in the coupling region and within the slab waveguide. The coupling structure includes two materials having different indices of refraction arranged as a grating defined by a grating period. The junction region comprises a p-n junction in communication with electrical contacts for biasing and collection of carriers resulting from absorption of incident radiation.

Abstract translation: 2维传感器阵列包括半导体衬底和设置在半导体衬底上的多个像素。 每个像素包括耦合区域和结区域，以及设置在半导体衬底上并从耦合区域延伸到该区域的平板波导结构。 平板波导包括设置在第一包层和第二包层之间的限制层。 第一包层和第二包层各自具有低于限制层的折射率的折射率。 每个像素还包括设置在耦合区域中并且在平板波导内的耦合结构。 耦合结构包括具有不同的折射率布置为由光栅周期限定的光栅的两种材料。 结区域包括与电触点连通的p-n结，用于偏移和收集由吸收入射辐射引起的载流子。

公开(公告)号：WO2015191557A1

公开(公告)日：2015-12-17

申请号：PCT/US2015/034868

申请日：2015-06-09

Applicant: STC.UNM

Inventor： BRUECK, Steven, R., J. ,  NEUMANN, Alexander ,  ZARKESH-HA, Payman

IPC: H01L33/58 ,  H01L33/48 ,  F21S2/00

CPC classification number: G01J1/06 ,  G01J1/44 ,  G01J3/0218 ,  G01J3/0259 ,  G01J3/18 ,  G01J3/1895 ,  G01J3/2803 ,  G01J2001/448 ,  G02B6/00 ,  G02B6/10 ,  G02B6/12004 ,  G02B6/122 ,  G02B6/124 ,  H01L27/1446 ,  H01L31/02019 ,  H01L31/02164 ,  H01L31/02327 ,  H01L31/103

Abstract: A 2-D sensor array includes a semiconductor substrate and a plurality of pixels disposed on the semiconductor substrate. Each pixel includes a coupling region and a junction region, and a slab waveguide structure disposed on the semiconductor substrate and extending from the coupling region to the region. The slab waveguide includes a confinement layer disposed between a first cladding layer and a second cladding layer. The first cladding and the second cladding each have a refractive index that is lower than a refractive index of the confinement layer. Each pixel also includes a coupling structure disposed in the coupling region and within the slab waveguide. The coupling structure includes two materials having different indices of refraction arranged as a grating defined by a grating period. The junction region comprises a p-n junction in communication with electrical contacts for biasing and collection of carriers resulting from absorption of incident radiation.

Abstract translation: 2维传感器阵列包括半导体衬底和设置在半导体衬底上的多个像素。 每个像素包括耦合区域和结区域，以及设置在半导体衬底上并从耦合区域延伸到该区域的平板波导结构。 平板波导包括设置在第一包层和第二包层之间的限制层。 第一包层和第二包层各自具有低于限制层的折射率的折射率。 每个像素还包括设置在耦合区域中并且在平板波导内的耦合结构。 耦合结构包括具有不同折射率的两种材料，其布置为由光栅周期限定的光栅。 结区域包括与电触点连通的p-n结，用于偏移和收集由吸收入射辐射引起的载流子。

公开(公告)号：WO2013049504A1

公开(公告)日：2013-04-04

申请号：PCT/US2012/057821

申请日：2012-09-28

Applicant: STC.UNM ,  EDWARDS, Jeremy ,  ZARKESH-HA, Payman ,  BRUECK, Steven, R.J.

Inventor： EDWARDS, Jeremy ,  ZARKESH-HA, Payman ,  BRUECK, Steven, R.J.

IPC: C12Q1/68 ,  C12N15/10 ,  C12N15/11

CPC classification number: C12Q1/6869 ,  C12Q1/6806 ,  C12Q1/6874 ,  G01N27/414 ,  G01N27/4145 ,  Y10T436/143333 ,  C12Q2531/125 ,  C12Q2535/122

Abstract: This disclosure describes, in one aspect, a method for preparing DNA molecule for sequencing. Generally, the method includes fragmenting the DNA molecule into double-stranded fragments; amplifying at least a portion of the double-stranded fragments; circularizing the fragments so that the first end of the fragment comprises a first loop connecting the strands and the second end of the fragment comprises a second loop connecting the strands; annealing a first sequencing primer to the first loop oriented to sequence at least a portion of one strand of the fragment; and annealing a second sequencing primer to the second loop oriented to sequence at least a portion of the other strand of the fragment. In another aspect, this disclosure describes a method for sequencing a DNA molecule. Generally, the method includes fragmenting the DNA molecule into double-stranded fragments; amplifying at least a portion of the double-stranded fragments; circularizing the fragments so that the first end of the fragment comprises a first loop connecting the strands and the second end of the fragment comprises a second loop connecting the strands; and sequencing at least one of the DNA strands.

Abstract translation: 本公开一方面描述了用于测序的DNA分子的制备方法。 通常，该方法包括将DNA分子分成双链片段; 扩增至少一部分双链片段; 使片段环化，使得片段的第一端包含连接线束的第一环和片段的第二端包括连接线的第二环; 将第一测序引物退火至所述第一环以定向以序列所述片段的一条链的至少一部分; 以及将第二测序引物退火至所述第二环，其定向为序列所述片段的另一条链的至少一部分。 在另一方面，本公开描述了用于测序DNA分子的方法。 通常，该方法包括将DNA分子分成双链片段; 扩增至少一部分双链片段; 使片段环化，使得片段的第一端包含连接线束的第一环和片段的第二端包括连接线的第二环; 并测序至少一个DNA链。

公开(公告)号：WO2013049463A2

公开(公告)日：2013-04-04

申请号：PCT/US2012/057758

申请日：2012-09-28

Applicant: STC.UNM ,  ZARKESH-HA, Payman ,  BRUECK, Steven, R.J. ,  EDWARDS, Jeremy

Inventor： ZARKESH-HA, Payman ,  BRUECK, Steven, R.J. ,  EDWARDS, Jeremy

CPC classification number: C12Q1/6869 ,  C12Q1/6806 ,  C12Q1/6874 ,  G01N27/414 ,  G01N27/4145 ,  Y10T436/143333 ,  C12Q2531/125 ,  C12Q2535/122

Abstract: Devices that include a substrate; a source region and a drain region formed within the substrate and having a channel region provided therebetween; a first insulating layer formed over the channel region; a first floating gate formed over the first insulating layer, the first floating gate configured to respond to an analyte in a target material; and a second gate formed over the first floating gate, the second gate capacatively coupled but not electrically connected to the first floating gate.

Abstract translation:

包含衬底的器件; 源极区域和漏极区域，形成在所述衬底内并具有设置在其间的沟道区; 形成在沟道区上的第一绝缘层; 形成在所述第一绝缘层上方的第一浮置栅极，所述第一浮置栅极配置为响应靶材料中的分析物; 以及形成在第一浮置栅极之上的第二栅极，第二栅极电容耦合但不电连接到第一浮置栅极。