公开(公告)号：HUE061271T2

公开(公告)日：2023-06-28

申请号：HUE18888579

申请日：2018-12-14

Applicant: STEALTH BIOTHERAPEUTICS INC

Inventor： ZHENG GUOZHU ,  BAMBERGER MARK ,  SMUKSTE INESE

IPC: A61K38/07 ,  A61P9/10 ,  C07K5/09

公开(公告)号：AU2013296493B2

公开(公告)日：2018-04-26

申请号：AU2013296493

申请日：2013-07-31

Applicant: STEALTH BIOTHERAPEUTICS INC

Inventor： BAMBERGER MARK ,  BLAKEY BRIAN ,  WILSON D TRAVIS

IPC: A61K38/08

Abstract: Disclosed herein are methods and compositions for preventing or treating atherosclerosis in a mammalian subject. The methods comprise administering to the subject an effective amount of an aromatic-cationic peptide and, in some applications, a second active agent, to subjects in need thereof. The present technology relates to the treatment or prevention of atherosclerosis in mammals through the administration of a therapeutically effective amount of aromatic cationic peptides and, in some embodiments, a second active agent.

公开(公告)号：ES2942631T3

公开(公告)日：2023-06-05

申请号：ES18888579

申请日：2018-12-14

Applicant: STEALTH BIOTHERAPEUTICS INC

Inventor： ZHENG GUOZHU ,  BAMBERGER MARK ,  SMUKSTE INESE

IPC: A61K38/07 ,  A61P9/10 ,  C07K5/09

Abstract: Se describen péptidos no naturales útiles para el tratamiento y la prevención de lesión por isquemia-reperfusión (p. ej., lesión por isquemia-reperfusión cardiaca) o infarto de miocardio. (Traducción automática con Google Translate, sin valor legal)

公开(公告)号：FI3723783T3

公开(公告)日：2023-03-24

申请号：FI18888579

申请日：2018-12-14

Applicant: STEALTH BIOTHERAPEUTICS INC

Inventor： ZHENG GUOZHU ,  BAMBERGER MARK ,  SMUKSTE INESE

Abstract: Disclosed are non-natural peptides useful for the treatment and prevention of ischemia-reperfusion injury (e.g., cardiac ischemia-reperfusion injury) or myocardial infarction.

公开(公告)号：LT3723783T

公开(公告)日：2023-03-27

申请号：LTUS2018065755

申请日：2018-12-14

Applicant: STEALTH BIOTHERAPEUTICS INC

Inventor： ZHENG GUOZHU ,  BAMBERGER MARK ,  SMUKSTE INESE

IPC: A61K38/07 ,  A61P9/10 ,  C07K5/09

公开(公告)号：AU2013296494B2

公开(公告)日：2018-04-26

申请号：AU2013296494

申请日：2013-07-31

Applicant: STEALTH BIOTHERAPEUTICS INC

Inventor： BAMBERGER MARK ,  BLAKEY BRIAN ,  ANDERSEN MARC W ,  WILSON D TRAVIS

IPC: A61K38/00

Abstract: Disclosed herein are methods and compositions for preventing or treating atherosclerosis in a mammalian subject. The methods comprise administering to the subject an effective amount of an aromatic-cationic peptide and in some applications, a second active agent chemically linked to the peptide, to subjects in need thereof.