公开(公告)号：AU2017265013B9

公开(公告)日：2019-05-02

申请号：AU2017265013

申请日：2017-11-21

Applicant: STEALTH BIOTHERAPEUTICS INC

Inventor： WILSON D TRAVIS

IPC: A61K38/07

Abstract: The disclosure relates to methods for treating a subject suffering from hyperalgesia caused by drug-induced neuropathy by administering to the subject an effective amount of an aromatic-cationic peptide. The disclosure also relates to methods for protecting a subject from hyperalgesia caused by drug-induced neuropathy by administering an effective amount of an aromatic-cationic peptide to a subject at risk for developing the condition.

公开(公告)号：AU2013296493B2

公开(公告)日：2018-04-26

申请号：AU2013296493

申请日：2013-07-31

Applicant: STEALTH BIOTHERAPEUTICS INC

Inventor： BAMBERGER MARK ,  BLAKEY BRIAN ,  WILSON D TRAVIS

IPC: A61K38/08

Abstract: Disclosed herein are methods and compositions for preventing or treating atherosclerosis in a mammalian subject. The methods comprise administering to the subject an effective amount of an aromatic-cationic peptide and, in some applications, a second active agent, to subjects in need thereof. The present technology relates to the treatment or prevention of atherosclerosis in mammals through the administration of a therapeutically effective amount of aromatic cationic peptides and, in some embodiments, a second active agent.

公开(公告)号：AU2017267969A1

公开(公告)日：2018-12-13

申请号：AU2017267969

申请日：2017-05-19

Applicant: STEALTH BIOTHERAPEUTICS INC

Inventor： WILSON D TRAVIS

IPC: A61P27/12 ,  A61K38/07 ,  A61K45/06 ,  A61K47/54 ,  A61K47/64 ,  A61P27/02 ,  C07K5/10

Abstract: The disclosure provides methods of preventing or treating mitochondrial myopathy in a mammalian subject, reducing risk factors associated with mitochondrial myopathy, and/or reducing the likelihood or severity of mitochondrial myopathy. The methods comprise administering to the subject an effective amount of an aromatic-cationic peptide.

公开(公告)号：AU2013296494B2

公开(公告)日：2018-04-26

申请号：AU2013296494

申请日：2013-07-31

Applicant: STEALTH BIOTHERAPEUTICS INC

Inventor： BAMBERGER MARK ,  BLAKEY BRIAN ,  ANDERSEN MARC W ,  WILSON D TRAVIS

IPC: A61K38/00

Abstract: Disclosed herein are methods and compositions for preventing or treating atherosclerosis in a mammalian subject. The methods comprise administering to the subject an effective amount of an aromatic-cationic peptide and in some applications, a second active agent chemically linked to the peptide, to subjects in need thereof.

公开(公告)号：AU2013237827B2

公开(公告)日：2017-12-14

申请号：AU2013237827

申请日：2013-03-29

Applicant: STEALTH BIOTHERAPEUTICS INC

Inventor： WILSON D TRAVIS

IPC: A61K38/07

Abstract: The disclosure relates to methods for treating a subject suffering from hyperalgesia caused by drug-induced neuropathy by administering to the subject an effective amount of an aromatic-cationic peptide. The disclosure also relates to methods for protecting a subject from hyperalgesia caused by drug-induced neuropathy by administering an effective amount of an aromatic-cationic peptide to a subject at risk for developing the condition.