公开(公告)号：AU2016316824A1

公开(公告)日：2018-04-26

申请号：AU2016316824

申请日：2016-09-05

Applicant: STICHTING KATHOLIEKE UNIV

Inventor： FEITZ WOUTER FRANCISCUS JOANNES ,  OOSTERWIJK EGBERT ,  MIHAILA SILVIA MARIA ,  ROWAN ALAN EDWARD

IPC: C12N5/00 ,  C08G65/325 ,  C08G65/333 ,  C12N5/077 ,  C12N5/0775

Abstract: The invention is directed to a cell culture comprising: a) a cell culturing medium for growing stem cells, b) a three-dimensional (3D) cell growth matrix and c) stem cells, wherein the cell culture has a critical stress σ

公开(公告)号：CA2997518A1

公开(公告)日：2017-03-09

申请号：CA2997518

申请日：2016-09-05

Applicant: STICHTING KATHOLIEKE UNIV

Inventor： FEITZ WOUTER FRANCISCUS JOANNES ,  OOSTERWIJK EGBERT ,  MIHAILA SILVIA MARIA ,  ROWAN ALAN EDWARD

IPC: C12N5/00 ,  C08G65/325 ,  C08G65/333 ,  C12N5/077 ,  C12N5/0775

Abstract: The invention is directed to a cell culture comprising: a) a cell culturing medium for growing stem cells, b) a three-dimensional (3D) cell growth matrix and c) stem cells, wherein the cell culture has a critical stress sc of 2-30 Pa, wherein the critical stress is a stress which marks an onset of strain stiffening and wherein the cell culture has a storage modulus G' measured at 37°C of 50-1000 Pa.