公开(公告)号：WO2021086180A1

公开(公告)日：2021-05-06

申请号：PCT/NL2020/050666

申请日：2020-10-28

Applicant: STICHTING VUMC

Inventor： GARCIA VALLEJO, Juan Jesus ,  KALAY, Hakan

IPC: A61K47/00 ,  B82Y5/00 ,  C12Q1/6816

Abstract: The invention relates to an isotope-containing tag, a method of preparing an isotope-containing tag, a tracer comprising an isotope-containing tag, a method of preparing a tracer, a method of labeling biological material, a use of the isotope-containing tag, a kit-of-parts for preparing a tracer. The isotope-containing tag comprises a monodisperse backbone to which at least one ligand and at least one functional group for attaching the backbone to a macromolecule are attached, wherein essentially every ligand attached to the backbone comprises an isotope.