公开(公告)号：WO2019039937A8

公开(公告)日：2019-02-28

申请号：PCT/NL2018/050547

申请日：2018-08-20

Applicant: STICHTING VUMC

Inventor： JANSEN, Gerrit ,  PETERS, Godefridus Johannes ,  OSSENKOPPELE, Gerrit Johan

IPC: A61K31/195 ,  A61K31/216 ,  A61K31/22 ,  A61K31/366 ,  A61K31/40 ,  A61K31/404 ,  A61K31/47 ,  A61K31/505 ,  A61K45/06 ,  A61P35/00 ,  A61P35/02

Abstract: The invention relates to a composition comprising a statin and an aminopeptidase inhibitor. Said composition may be used as a medicament, including in a method of treating cancer, such as a hematological cancer. The invention further relates to methods of treating a cancer in an individual, and to a use of an aminopeptidase inhibitor in a method for the preparation of a medicament for the treatment of a cancer.

公开(公告)号：WO2019039937A1

公开(公告)日：2019-02-28

申请号：PCT/NL2018/050547

申请日：2018-08-20

Applicant: STICHTING VUMC

Inventor： JANSEN, Gerrit ,  PETERS, Godefridus Johannes

IPC: A61K31/195 ,  A61K31/216 ,  A61K31/22 ,  A61K31/366 ,  A61K31/40 ,  A61K31/404 ,  A61K31/47 ,  A61K31/505 ,  A61K45/06 ,  A61P35/00 ,  A61P35/02

CPC classification number: A61K31/195 ,  A61K31/216 ,  A61K31/22 ,  A61K31/366 ,  A61K31/40 ,  A61K31/404 ,  A61K31/47 ,  A61K31/505 ,  A61K45/06 ,  A61K2300/00

Abstract: The invention relates to a composition comprising a statin and an aminopeptidase inhibitor. Said composition may be used as a medicament, including in a method of treating cancer, such as a hematological cancer. The invention further relates to methods of treating a cancer in an individual, and to a use of an aminopeptidase inhibitor in a method for the preparation of a medicament for the treatment of a cancer.