公开(公告)号：WO1995027436A1

公开(公告)日：1995-10-19

申请号：PCT/US1995004177

申请日：1995-04-05

Applicant: SUMMIT TECHNOLOGY, INC.

Inventor： SUMMIT TECHNOLOGY, INC. ,  MULLER, David, F. ,  D'AGATI, Mike ,  FRIEDMAN, Marc ,  HARMON, Troy ,  KLOPOTEK, Peter ,  SACHAROFF, Alex ,  SHERR, Evan

IPC: A61B05/05

CPC classification number: A61F9/008 ,  A61F9/00804 ,  A61F9/00817 ,  A61F2009/00844 ,  A61F2009/00872

Abstract: The invention features improvements in PRK procedures that relate to preventing non-uniform removal of material from the corneal surface. It has been realized that protoablation by-products resulting during the PRK procedure can affect the accuracy and the predictability of the procedure. Under certain conditions, the plume of photoablation by-products (44) that have left the corneal surface (60) can non-uniformly redeposit onto the ablation area and thus affect the uniformity of subsequent material removal. The plume of photoablation by-products, in the space above the corneal surface, can also non-uniformly affect the escape of further photoablation products from the surface. In addition to the plume effects, it has been realized that the hydration level of the corneal tissue during the PRK procedure can vary over the ablation area and likewise non-uniformly affect the PRK procedure.

Abstract translation: 本发明的特征在于PRK程序的改进涉及防止材料从角膜表面的不均匀去除。 已经意识到，在PRK程序期间产生的原型化副产物可能影响程序的准确性和可预测性。 在某些条件下，离开角膜表面（60）的光消除副产物（44）的羽毛可能不均匀地再沉积到消融区域上，从而影响随后的材料去除的均匀性。 在角膜表面以上的空间中，光消融副产物的羽毛也可以不均匀地影响进一步的光消化产物从表面的逸出。 除了羽流效应之外，已经认识到在PRK程序期间角膜组织的水合水平可以在消融区域上变化，并且同样不均匀地影响PRK程序。