公开(公告)号：US20170087089A1

公开(公告)日：2017-03-30

申请号：US15282267

申请日：2016-09-30

Applicant: SUN PHARMA ADVANCED RESEARCH COMPANY LTD

Inventor： Sachin Pushkarray Naik ,  Ujjawal Jayantilal Seju ,  Subhas Balaram Bhowmick

IPC: A61K9/127 ,  A61K31/7048

CPC classification number: A61K9/127 ,  A61K9/1277 ,  A61K31/7048

Abstract: The present invention relates to a process for the preparation of unilamellar liposomal composition of a polyene antibiotic drug. The present invention further relates to liposomal composition of a polyene antibiotic drug that is stable.

公开(公告)号：US10512608B2

公开(公告)日：2019-12-24

申请号：US15552966

申请日：2016-02-25

Applicant: SUN PHARMA ADVANCED RESEARCH COMPANY LTD.

Inventor： Madhusudhan Bommagani ,  Subhas Balaram Bhowmick ,  Prashant Kane ,  Vaibhav Dubey

IPC: A61K9/14 ,  A61K31/65 ,  A61K9/00 ,  A61K9/06 ,  A61K9/10 ,  A61K9/12 ,  A61K47/14

Abstract: The present invention relates to a nanoparticulate topical composition comprising (i) nanoparticles of a water soluble and water susceptible active ingredient or its pharmaceutically acceptable salt, having a particle size distribution such that 90% of the particles are less than 1000 nm, (ii) one or more wetting agent and (iii) a non-aqueous liquid vehicle, wherein the composition is free of water.The present invention also relates to a method of treating acne, rosacea, impetigo or a skin disease caused by a bacteria, by topical application of a nanoparticulate topical composition comprising nanoparticles of a water soluble and water susceptible active ingredient or its pharmaceutically acceptable salt, having a particle size distribution such that 90% of the particles are less than 1000 nm.

公开(公告)号：US09539262B2

公开(公告)日：2017-01-10

申请号：US14691167

申请日：2015-04-20

Applicant: SUN PHARMA ADVANCED RESEARCH COMPANY, LTD.

Inventor： Ajay Jaysingh Khopade ,  Arindam Halder ,  Subhas Balaram Bhowmick

IPC: A61K31/5575 ,  A61K47/14 ,  A61K9/00 ,  A61K9/107 ,  A61K31/00

CPC classification number: A61K31/5575 ,  A61K9/0048 ,  A61K9/1075 ,  A61K31/00 ,  A61K47/14

Abstract: The present invention relates to a pharmaceutical composition suitable for ophthalmic use comprising one or more prostaglandin derivatives or salts, a stabilizing amount of polyethylene glycol hydroxystearate and pharmaceutically acceptable vehicle.

Abstract translation: 本发明涉及适用于眼用的药物组合物，其包含一种或多种前列腺素衍生物或盐，稳定量的聚乙二醇羟基硬脂酸酯和药学上可接受的载体。