公开(公告)号：WO2016013031A1

公开(公告)日：2016-01-28

申请号：PCT/IN2015/050073

申请日：2015-07-23

Applicant: SUN PHARMA ADVANCED RESEARCH COMPANY LTD.

Inventor： BHOWMICK, Subhas ,  UMRETHIA, Manish Kumar ,  MAITI, Kuntal ,  HADIA, Jayesh Kumar ,  PATEL, Nitesh Kumar

IPC: A61K9/127 ,  A61K9/107 ,  A61K31/4178

CPC classification number: A61K31/4178 ,  A61K9/0019 ,  A61K9/1271 ,  A61K31/41 ,  A61K31/4184 ,  A61K31/4245

Abstract: The present invention relates to a method of loading an ionizable drug having a group selected from (Formule I or Formule II) or pharmaceutically acceptable salts thereof into a liposome and the liposomal composition of drug produced therewith.

Abstract translation: 本发明涉及一种将具有选自（Formule I或Formule II）或其药学上可接受的盐的可离子化药物加载到脂质体中的方法和由其制备的药物的脂质体组合物。

公开(公告)号：WO2016199169A1

公开(公告)日：2016-12-15

申请号：PCT/IN2016/050175

申请日：2016-06-08

Applicant: SUN PHARMA ADVANCED RESEARCH COMPANY LTD

Inventor： MA, Wen Wee ,  ADJEI, Alex ,  BUI, Lynne ,  HARNING, Ronald ,  KHOPADE, Ajay ,  BHOWMICK, Subhas ,  ARULSUDAR, Natarajan ,  LAKKAD, Narendra

IPC: A61K9/107 ,  A61K9/51 ,  A61K31/337

CPC classification number: A61K9/10 ,  A61K9/0019 ,  A61K9/5123 ,  A61K9/5138 ,  A61K9/5146 ,  A61K31/337 ,  A61K47/10 ,  A61K47/12 ,  A61K47/28 ,  A61K47/32 ,  A61P35/00

Abstract: A method of treating patients suffering from carcinoma of intrahepatic or extra hepatic bile duct or gall bladder which is locally advanced or metastatic, by intravenously administering to the patient, paclitaxel in the form of a nanodispersion. The nanodispersion comprises particles with a mean particle size less than 300 nm and is free of polyoxyethylated castor oil and free of a protein.

Abstract translation: 通过静脉内施用纳米分散体形式的紫杉醇，治疗局部晚期或转移的肝内或肝外胆管癌或胆囊癌患者的方法。 纳米分散体包含平均粒度小于300nm的颗粒，并且不含聚氧乙烯化蓖麻油并且不含蛋白质。

公开(公告)号：WO2011145109A1

公开(公告)日：2011-11-24

申请号：PCT/IN2011/000337

申请日：2011-05-13

Applicant: SUN PHARMA ADVANCED RESEARCH COMPANY LTD., ,  BHOWMICK, Subhas ,  KANE, Prashant ,  S, Ganesh ,  PATEL, Tarun ,  CHUDIWAL, Swapnil

Inventor： BHOWMICK, Subhas ,  KANE, Prashant ,  S, Ganesh ,  PATEL, Tarun ,  CHUDIWAL, Swapnil

IPC: A61K9/00 ,  A61K31/137

CPC classification number: A61K31/137 ,  A61K9/0075 ,  A61K9/145

Abstract: The dry powder inhalation composition comprising: (1) salmeterol xinafoate having mean particle size in range of 2.0 μ - 6 μ microns and a tapped density in the range of 0.20 g.com -3 to 0.45 g.com -3 and (2) optionally, one or more other active ingredients and pharmaceutically acceptable carrier.

Abstract translation: 所述干粉吸入组合物包含：（1）平均粒度在2.0微米-6微米范围内的轻度密度和0.20g.com -3至0.45g.com -3和（2）范围内的敲击密度的沙美特罗昔萘酸盐， 任选地，一种或多种其它活性成分和药学上可接受的载体。

公开(公告)号：WO2011138802A1

公开(公告)日：2011-11-10

申请号：PCT/IN2011/000321

申请日：2011-05-06

Applicant: SUN PHARMA ADVANCED RESEARCH COMPANY LTD., ,  NAMDEO, Alok ,  BHADRA, Sulekha ,  KHATRI, Hiren ,  BHOWMICK, Subhas

Inventor： NAMDEO, Alok ,  BHADRA, Sulekha ,  KHATRI, Hiren ,  BHOWMICK, Subhas

IPC: A61K38/26 ,  C07K14/605 ,  A61K9/08

CPC classification number: C07K14/605 ,  A61K9/0019 ,  A61K9/1075 ,  A61K38/26 ,  A61K47/12 ,  A61K47/183 ,  A61K47/20 ,  A61K47/24 ,  A61K47/26

Abstract: The present invention provides a stable ready-to-use solution comprising therapeutically effective amounts of glucagon together with pegylated distearoyl-phosphatidylethanolamine.

Abstract translation: 本发明提供了一种稳定的即用型溶液，其包含治疗有效量的胰高血糖素以及聚乙二醇化二硬脂酰磷脂酰乙醇胺。

公开(公告)号：EP3150196A1

公开(公告)日：2017-04-05

申请号：EP16191594.7

申请日：2016-09-29

Applicant: Sun Pharma Advanced Research Company Ltd

Inventor： NAIK, Sachin ,  SEJU, Ujjawal ,  BHOWMICK, Subhas

IPC: A61K9/127 ,  A61K31/7048

CPC classification number: A61K9/127 ,  A61K9/1277 ,  A61K31/7048

Abstract: The present invention relates to a process for the preparation of unilamellar liposomal composition of a polyene antibiotic drug. The present invention further relates to liposomal composition of a polyene antibiotic drug that is stable.

Abstract translation: 本发明涉及一种制备多烯抗生素药物的单层脂质体组合物的方法。 本发明还涉及稳定的多烯抗生素药物的脂质体组合物。

公开(公告)号：EP2571486A1

公开(公告)日：2013-03-27

申请号：EP11783170.1

申请日：2011-05-13

Applicant: Sun Pharma Advanced Research Company Ltd

Inventor： BHOWMICK, Subhas ,  KANE, Prashant ,  S, Ganesh ,  PATEL, Tarun ,  CHUDIWAL, Swapnil

IPC: A61K9/00 ,  A61K31/137

CPC classification number: A61K31/137 ,  A61K9/0075 ,  A61K9/145

Abstract: The dry powder inhalation composition comprising (1) salmeterol xinafoate having mean particle size in range of 2.0μ-6μ microns and a tapped density in the range of 0.20 g·cm−3 to 0.45 g·cm−3 and (2) optionally, one or more other active ingredients and pharmaceutically acceptable carrier.

Abstract translation: 所述干粉吸入组合物包含（1）平均粒径为2.0μ-6μ微米的海洛英醇海绵酸新甲酯，并且在0.20g·cm -3〜0.45g·cm -3的范围内的抽头密度和（2）任选地， 一种或多种其它活性成分和药学上可接受的载体。