公开(公告)号：WO1998015969A3

公开(公告)日：1998-04-16

申请号：PCT/US1997018147

申请日：1997-10-08

Applicant: SYMYX TECHNOLOGIES

Inventor： SYMYX TECHNOLOGIES ,  WEINBERG, W., Henry ,  MCFARLAND, Eric, W. ,  CONG, Peijun ,  GUAN, Shenheng

IPC: H01J49/00

Abstract: Methods and apparatus for screening diverse arrays of materials are provided. In particular, techniques are provided for rapidly characterizing compounds in combinatorial arrays of materials for discovering and/or optimizing new materials with specific desired properties. According to one aspect, a scanning mass spectrometer is used which includes an ionization chamber and a collector that outputs an electrical signal responsive to the quantity of gas ions contacting the collector surface. A conduit system selectively withdraws samples from the array of materials, passing the samples into the ionization chamber. In a specific embodiment, reactants are passed through the conduit system to the selected regions of interest on the substrate. Means are provided to selectively heat regions on the substrate.

公开(公告)号：EP1080435B1

公开(公告)日：2002-02-27

申请号：EP99955064.3

申请日：1999-10-19

Applicant: Symyx Technologies, Inc.

Inventor： LACY, Steven, D. ,  MCFARLAND, Eric, W. ,  SAFIR, Adam, L. ,  TURNER, Stephen, J. ,  VAN ERDEN, Lynn ,  WANG, Pei

IPC: G06F17/50

CPC classification number: C40B50/02 ,  B01J19/0046 ,  B01J2219/00477 ,  B01J2219/00479 ,  B01J2219/00495 ,  B01J2219/00689 ,  B01J2219/00695 ,  B01J2219/00698 ,  B01J2219/007 ,  C40B60/14

Abstract: Computer-implemented methods, programs and apparatus for generating a library design for a combinatorial library of materials. A library design includes a set of sources representing components to be used in preparing the combinatorial library, destinations representing arrangements of cells and mappings, defining one or more distribution patterns for assigning components to cells in the destination arrangement or arrangements. Mappings include gradients and sets of user-defined equations, and are used to calculate the amount of one or more components to be assigned to a cell or cells in an arrangement. A library design can also include one or more process parameters defined to vary over time or across a plurality of destination cells. The invention outputs a data file defining the library design, including electronic data representing the sources, the destinations and the mapping, in a format suitable for implementing manually or using automated material handling apparatus.

公开(公告)号：EP1019947B1

公开(公告)日：2002-08-14

申请号：EP97910017.9

申请日：1997-10-08

Applicant: Symyx Technologies, Inc.

Inventor： WEINBERG, W., Henry ,  MCFARLAND, Eric, W. ,  CONG, Peijun ,  GUAN, Shenheng

IPC: H01J49/00

CPC classification number: G01N29/2425 ,  B01J19/0046 ,  B01J2219/00315 ,  B01J2219/00317 ,  B01J2219/00364 ,  B01J2219/00378 ,  B01J2219/0043 ,  B01J2219/00443 ,  B01J2219/00497 ,  B01J2219/005 ,  B01J2219/00511 ,  B01J2219/00515 ,  B01J2219/0052 ,  B01J2219/00527 ,  B01J2219/00536 ,  B01J2219/00583 ,  B01J2219/00585 ,  B01J2219/0059 ,  B01J2219/00596 ,  B01J2219/00605 ,  B01J2219/0061 ,  B01J2219/00612 ,  B01J2219/00621 ,  B01J2219/00626 ,  B01J2219/00628 ,  B01J2219/00637 ,  B01J2219/00641 ,  B01J2219/00659 ,  B01J2219/00675 ,  B01J2219/00689 ,  B01J2219/00702 ,  B01J2219/00704 ,  B01J2219/00722 ,  B01J2219/00738 ,  B01J2219/00745 ,  B01J2219/00747 ,  B01J2219/0075 ,  B01J2219/00754 ,  B82Y30/00 ,  C07F15/0066 ,  C07F15/045 ,  C40B20/08 ,  C40B30/08 ,  C40B40/14 ,  C40B40/18 ,  C40B50/14 ,  C40B60/12 ,  C40B60/14 ,  G01H13/00 ,  G01J4/00 ,  G01N9/002 ,  G01N11/16 ,  G01N21/211 ,  G01N21/253 ,  G01N21/6402 ,  G01N21/6452 ,  G01N21/66 ,  G01N25/4813 ,  G01N29/022 ,  G01N29/036 ,  G01N29/2418 ,  G01N29/30 ,  G01N29/348 ,  G01N29/42 ,  G01N29/4418 ,  G01N29/4427 ,  G01N31/10 ,  G01N2009/006 ,  G01N2203/0094 ,  G01N2291/014 ,  G01N2291/0224 ,  G01N2291/0255 ,  G01N2291/0256 ,  G01N2291/02818 ,  G01N2291/02827 ,  G01N2291/02863 ,  G01N2291/0422 ,  G01N2291/0423 ,  G01N2291/0427 ,  G01N2291/106 ,  H01J49/0409 ,  H01J49/0468

公开(公告)号：EP1080435A1

公开(公告)日：2001-03-07

申请号：EP99955064.3

申请日：1999-10-19

Applicant: Symyx Technologies, Inc.

Inventor： LACY, Steven, D. ,  MCFARLAND, Eric, W. ,  SAFIR, Adam, L. ,  TURNER, Stephen, J. ,  VAN ERDEN, Lynn ,  WANG, Pei

IPC: G06F17/50

CPC classification number: C40B50/02 ,  B01J19/0046 ,  B01J2219/00477 ,  B01J2219/00479 ,  B01J2219/00495 ,  B01J2219/00689 ,  B01J2219/00695 ,  B01J2219/00698 ,  B01J2219/007 ,  C40B60/14

Abstract: Computer-implemented methods, programs and apparatus for generating a library design for a combinatorial library of materials. A library design includes a set of sources representing components to be used in preparing the combinatorial library, destinations representing arrangements of cells and mappings, defining one or more distribution patterns for assigning components to cells in the destination arrangement or arrangements. Mappings include gradients and sets of user-defined equations, and are used to calculate the amount of one or more components to be assigned to a cell or cells in an arrangement. A library design can also include one or more process parameters defined to vary over time or across a plurality of destination cells. The invention outputs a data file defining the library design, including electronic data representing the sources, the destinations and the mapping, in a format suitable for implementing manually or using automated material handling apparatus.

公开(公告)号：EP1019947A2

公开(公告)日：2000-07-19

申请号：EP97910017.9

申请日：1997-10-08

Applicant: SYMYX TECHNOLOGIES

Inventor： WEINBERG, W., Henry ,  MCFARLAND, Eric, W. ,  CONG, Peijun ,  GUAN, Shenheng

IPC: H01J49/00

CPC classification number: G01N29/2425 ,  B01J19/0046 ,  B01J2219/00315 ,  B01J2219/00317 ,  B01J2219/00364 ,  B01J2219/00378 ,  B01J2219/0043 ,  B01J2219/00443 ,  B01J2219/00497 ,  B01J2219/005 ,  B01J2219/00511 ,  B01J2219/00515 ,  B01J2219/0052 ,  B01J2219/00527 ,  B01J2219/00536 ,  B01J2219/00583 ,  B01J2219/00585 ,  B01J2219/0059 ,  B01J2219/00596 ,  B01J2219/00605 ,  B01J2219/0061 ,  B01J2219/00612 ,  B01J2219/00621 ,  B01J2219/00626 ,  B01J2219/00628 ,  B01J2219/00637 ,  B01J2219/00641 ,  B01J2219/00659 ,  B01J2219/00675 ,  B01J2219/00689 ,  B01J2219/00702 ,  B01J2219/00704 ,  B01J2219/00722 ,  B01J2219/00738 ,  B01J2219/00745 ,  B01J2219/00747 ,  B01J2219/0075 ,  B01J2219/00754 ,  B82Y30/00 ,  C07F15/0066 ,  C07F15/045 ,  C40B20/08 ,  C40B30/08 ,  C40B40/14 ,  C40B40/18 ,  C40B50/14 ,  C40B60/12 ,  C40B60/14 ,  G01H13/00 ,  G01J4/00 ,  G01N9/002 ,  G01N11/16 ,  G01N21/211 ,  G01N21/253 ,  G01N21/6402 ,  G01N21/6452 ,  G01N21/66 ,  G01N25/4813 ,  G01N29/022 ,  G01N29/036 ,  G01N29/2418 ,  G01N29/30 ,  G01N29/348 ,  G01N29/42 ,  G01N29/4418 ,  G01N29/4427 ,  G01N31/10 ,  G01N2009/006 ,  G01N2203/0094 ,  G01N2291/014 ,  G01N2291/0224 ,  G01N2291/0255 ,  G01N2291/0256 ,  G01N2291/02818 ,  G01N2291/02827 ,  G01N2291/02863 ,  G01N2291/0422 ,  G01N2291/0423 ,  G01N2291/0427 ,  G01N2291/106 ,  H01J49/0409 ,  H01J49/0468

Abstract: Methods and apparatus for screening diverse arrays of materials are provided. In particular, techniques are provided for rapidly characterizing compounds in combinatorial arrays of materials for discovering and/or optimizing new materials with specific desired properties. According to one aspect, a scanning mass spectrometer is used which includes an ionization chamber and a collector that outputs an electrical signal responsive to the quantity of gas ions contacting the collector surface. A conduit system selectively withdraws samples from the array of materials, passing the samples into the ionization chamber. In a specific embodiment, reactants are passed through the conduit system to the selected regions of interest on the substrate. Means are provided to selectively heat regions on the substrate.

Abstract translation: 提供了用于筛选各种材料阵列的方法和设备。 具体而言，提供了用于快速表征材料的组合阵列中的化合物的技术，以发现和/或优化具有特定期望性质的新材料。 根据一个方面，使用扫描质谱仪，其包括电离室和收集器，该收集器响应于接触收集器表面的气体离子的量输出电信号。 导管系统选择性地从材料阵列中取出样品，使样品进入电离室。 在具体的实施方式中，反应物通过导管系统到达基板上的选定感兴趣区域。 提供手段来选择性地加热衬底上的区域。