公开(公告)号：CA2351336C

公开(公告)日：2005-05-17

申请号：CA2351336

申请日：1999-12-03

Applicant: SYMYX TECHNOLOGIES INC

Inventor： NIELSEN RALPH B ,  SAFIR ADAM ,  TIEDE RICHARD ,  HAJDUK DAMIAN ,  FREITAG J CHRISTOPHER

IPC: G01N35/02 ,  B01J4/00 ,  B01J19/00 ,  B01J19/26 ,  C08F2/00 ,  C40B40/14 ,  C40B60/14 ,  G01N35/10

Abstract: A method and apparatus (10) for reacting a plurality of different mixtures in parallel in a semi-batch or continuous mode is provided. Each reaction is contained within a reactor vessel (102), the reactor vessels (102) combined into a reactor block (100). Reactant(s) to be added during the reaction are kept in a header barrel (202), which has a plunger (402) to feed reactant(s) from the header barrel (202) through a transfer line (302) into the reactor vessel (102). The plunger (402) is moved using a drive system (500). The header barrels (202) are optionally combined in a header block (200). The header block (200) is seated to a plate (300) containing the transfer lines (302), which in turn is sealed to the reactor block (100). A latch mechanism (600) is provided for easy sealing of the reactor (100) and header blocks (200) to the plate (300). The entire apparatus (10) may be placed on a rocker or rotating plate for mixture as the reaction is proceeding.

公开(公告)号：AU2041200A

公开(公告)日：2000-06-19

申请号：AU2041200

申请日：1999-12-03

Applicant: SYMYX TECHNOLOGIES INC

Inventor： FREITAG CHRISTOPHER J ,  HAJDUK DAMIAN ,  NIELSEN RALPH B ,  SAFIR ADAM ,  TIEDE RICHARD

IPC: G01N35/02 ,  B01J4/00 ,  B01J19/00 ,  B01J19/26 ,  C08F2/00 ,  C40B40/14 ,  C40B60/14 ,  G01N35/10

公开(公告)号：DE60224033D1

公开(公告)日：2008-01-24

申请号：DE60224033

申请日：2002-04-04

Applicant: SYMYX TECHNOLOGIES INC

Inventor： WHEELER TONY H ,  VAN ERDEN SANTA CLARA ,  CHANDLER WILLIAM H ,  TIEDE RICHARD ,  SAXTON ROBERT J ,  GURAM ANIL

IPC: B01J19/00 ,  C40B60/14 ,  F28F27/00

公开(公告)号：AT380585T

公开(公告)日：2007-12-15

申请号：AT02717780

申请日：2002-04-04

Applicant: SYMYX TECHNOLOGIES INC

Inventor： WHEELER TONY ,  VAN ERDEN LYNN ,  CHANDLER WILLIAM ,  TIEDE RICHARD ,  SAXTON ROBERT ,  GURAM ANIL

IPC: B01J19/00 ,  C40B60/14 ,  F28F27/00

公开(公告)号：AU5928901A

公开(公告)日：2001-12-24

申请号：AU5928901

申请日：2001-04-30

Applicant: SYMYX TECHNOLOGIES INC

Inventor： MANSKY PAUL ,  TIEDE RICHARD ,  HAVADTOY STEVE

IPC: B01J19/00 ,  B01L3/00 ,  G01N33/36 ,  G01N35/02

公开(公告)号：DE60224033T2

公开(公告)日：2009-02-26

申请号：DE60224033

申请日：2002-04-04

Applicant: SYMYX TECHNOLOGIES INC

Inventor： WHEELER TONY ,  VAN ERDEN LYNN ,  CHANDLER WILLIAM H ,  TIEDE RICHARD ,  SAXTON ROBERT ,  GURAM ANIL

IPC: B01J19/00 ,  C40B60/14 ,  F28F27/00

公开(公告)号：AU6533601A

公开(公告)日：2001-12-17

申请号：AU6533601

申请日：2001-06-01

Applicant: SYMYX TECHNOLOGIES INC

Inventor： NIELSEN RALPH B ,  SAFIR ADAM ,  TIEDE RICHARD ,  MCWAID THOMAS HARDING ,  ERDEN LYNN VAN

IPC: B01F7/00 ,  B01F7/16 ,  B01F15/00 ,  B01J19/00 ,  C40B40/14 ,  C40B60/14

Abstract: Parallel semi-continuous or continuous reactors are disclosed. The parallel reactors preferably comprise four or more reaction vessels. The reaction vessels are preferably small volume reaction vessels, preferably pressure reaction vessels, and/or preferably integral with a common reactor block. The reaction vessels can comprise shaft-driven stirrers. At least two, preferably at least three or at least four liquid feed lines can provide selective fluid communication between each of the reaction vessels and one or more liquid reagent sources. Additional features, suitable in connection with parallel reactors or with single reaction vessels are also disclosed.

公开(公告)号：CA2351336A1

公开(公告)日：2000-06-08

申请号：CA2351336

申请日：1999-12-03

Applicant: SYMYX TECHNOLOGIES INC

Inventor： FREITAG J CHRISTOPHER ,  TIEDE RICHARD ,  SAFIR ADAM ,  NIELSEN RALPH B ,  HAJDUK DAMIAN

IPC: G01N35/02 ,  B01J4/00 ,  B01J19/00 ,  B01J19/26 ,  C08F2/00 ,  C40B40/14 ,  C40B60/14 ,  G01N35/10

Abstract: A method and apparatus (10) for reacting a plurality of different mixtures i n parallel in a semi-batch or continuous mode is provided. Each reaction is contained within a reactor vessel (102), the reactor vessels (102) combined into a reactor block (100). Reactant(s) to be added during the reaction are kept in a header barrel (202), which has a plunger (402) to feed reactant(s) from the header barrel (202) through a transfer line (302) into the reactor vessel (102). The plunger (402) is moved using a drive system (500). The header barrels (202) are optionally combined in a header block (200). The header block (200) is sealed to a plate (300) containing the transfer lines (302), which in turn is sealed to the reactor block (100). A latch mechanism (600) is provided for easy sealing of the reactor (100) and header blocks (200) to the plate (300). The entire apparatus (10) may be placed on a rocke r or rotating plate for mixture as the reaction is proceeding.

公开(公告)号：WO02081076A3

公开(公告)日：2003-04-24

申请号：PCT/US0210935

申请日：2002-04-04

Applicant: SYMYX TECHNOLOGIES INC

Inventor： WHEELER TONY H ,  VAN ERDEN LYNN ,  CHANDLER WILLIAM H JR ,  TIEDE RICHARD ,  SAXTON ROBERT J ,  GURAM ANIL

IPC: B01J19/00 ,  C40B60/14 ,  F28F27/00

CPC classification number: F28F27/00 ,  B01J19/0046 ,  B01J2219/00155 ,  B01J2219/00283 ,  B01J2219/00308 ,  B01J2219/00351 ,  B01J2219/00477 ,  B01J2219/00481 ,  B01J2219/00495 ,  B01J2219/00585 ,  B01J2219/0059 ,  B01J2219/00698 ,  B01J2219/00718 ,  C40B60/14 ,  Y10T436/11 ,  Y10T436/142222

Abstract: A combinatorial chemistry reactor system for the parallel processing of reaction mixtures. The system comprises a frame, a head mounted in fixed position on the frame, and a reactor block having a plurality of wells therein for containing reaction mixtures. The reactor block is movable with respect to the head between a first position in which the reactor block and head are assembled for conducting reactions in the wells and a second position in which the reactor block is removed from the head for providing access to the vessels. Gaps in the reactor block between the wells serve to thermally isolate the wells from one another. Other features relating to pressure relief, reactor block temperature control, and sensor mounting are also disclosed.

Abstract translation: 用于并行处理反应混合物的组合化学反应器系统。 该系统包括框架，安装在框架上的固定位置的头部和反应器块，其中具有用于容纳反应混合物的多个孔。 反应器模块可相对于头部在第一位置和第二位置之间相对于第一位置移动，在第一位置，反应器块和头组装在其中以在井中进行反应，而在第二位置，反应器块从头部移除以提供对容器的通路。 两个井之间的反应器块中的间隙用于将孔彼此热隔离。 还公开了与减压，反应堆块温度控制和传感器安装相关的其它特征。

公开(公告)号：WO2007033334A2

公开(公告)日：2007-03-22

申请号：PCT/US2006035872

申请日：2006-09-14

Applicant: SYMYX TECHNOLOGIES INC ,  BERGH H SAM ,  CYPES STEPHEN ,  HAJDUK DAMIAN ,  HOGAN ZACH ,  TIEDE RICHARD

Inventor： BERGH H SAM ,  CYPES STEPHEN ,  HAJDUK DAMIAN ,  HOGAN ZACH ,  TIEDE RICHARD

IPC: G01N33/00

CPC classification number: G01N17/006

Abstract: Methods, apparatus and systems implementing techniques for screening compositions in a test environment. Test samples are exposed to one or more test fluids under controlled conditions. The test samples and/or test fluids are analyzed to detect an effect of the exposure.

Abstract translation: 实施在测试环境中筛选组合物的技术的方法，设备和系统。 在受控条件下将测试样品暴露于一种或多种测试流体。 分析测试样本和/或测试流体以检测暴露的影响。