公开(公告)号：DE10256353A1

公开(公告)日：2003-06-18

申请号：DE10256353

申请日：2002-12-03

Applicant: SYNGENTA PARTICIPATIONS AG

Inventor： EDMUNDS ANDREW ,  SCHAETZER JUERGEN ,  LUETHY CHISTOPH ,  DIGGELMANN MARTIN ,  LUTZ WILLIAM

IPC: A01N43/40 ,  A01N43/90 ,  A01N55/00 ,  C07D213/38 ,  C07D213/50 ,  C07D213/89 ,  C07D401/08 ,  C07D401/14 ,  C07D405/12 ,  C07D491/10 ,  A01N43/32 ,  A01N43/60 ,  C07D401/12 ,  C07D407/12 ,  C07D407/14

Abstract: 5-Amino-4-(pyridinylcarbonyl)-cyclohexene-1,3-dione derivatives (I) and their salts, all isomers and tautomers are new. 5-Amino-4-(pyridinylcarbonyl)-cyclohexene-1,3-dione derivatives of formula (I) and their salts, all isomers and tautomers are new. R1 = H, 1-12C alkyl, 2-12C alkenyl or alkynyl, 3-12C allenyl, 3-12C cycloalkyl, R3-(1-12C alkylene or 2-12C alkenylene) where alkylene and alkenylene may be interrupted by oxygen, S(O)n, NR21 or CO and substituted by R4, or phenyl (optionally substituted 1-5 times by R5), 3-12 membered, mono- or bi-cyclic ring system, aromatic, partly or fully saturated, optionally containing 1-5 heteroatoms (nitrogen, oxygen and/or sulfur) or 1-2 carbonyl, and optionally substituted by 1-3 R6, with the system attached through a C or N atom, directly or via a 1-6C alkylene or alkenylene chain, itself optionally interrupted by oxygen or S(O)n and/or substituted by R7, to which NR1R2, and substituents on N are other than halo or cyano, C(X1)X2R8, C(X3)NR9R10, 1-12C alkoxy or alkylthio; R2 = H, cyano, 1-12C (halo)alkyl, 2-12C (halo)alkenyl or (halo)alkynyl, 3-12C allenyl, 3-12C cycloalkyl, R11-(1-12C alkylene or 2-12C alkenylene) where alkylene and alkenylene may be interrupted by oxygen, or S(O)n and substituted by R12, or R2 and R1 are together 2-12C alkylene or alkenylene (optionally interrupted by 1-3 O, S(O)n, NR13 or CX4) and optionally substituted by 1-4 R14, or NR1R2 is pyrrolyl, pyrazolyl, imidazolyl, triazolyl or tetrazolyl, all but the last optionally substituted by 1-3 R15; n = 0-2; X1 = O or S; X2 = bond, O or S; X3 = O, S or NR21; X4 = O, S, OCH2CH2O or OCH2CH2CH2O; Y' = fluoro or chloro; and Q = N or N -O . Provided that R1 and R2 are not both hydrogen when Y' is fluoro. The full definitions are given in the DEFINITIONS (Full Definitions) Field. An Independent claim is also included for a method for making (I) by reacting the corresponding 5-halo compound (II) with HNR1R2, or its alkali or alkaline earth metal salt.