Blood sample tray apparatus
    1.
    发明授权
    Blood sample tray apparatus 失效
    血液样品托盘装置

    公开(公告)号:US3679129A

    公开(公告)日:1972-07-25

    申请号:US3679129D

    申请日:1970-09-08

    Abstract: New and improved sample processing and supply apparatus are disclosed and comprise tray means from which are pivotally supported a plurality of partially filled sample container means. In use, said tray means are operatively connected to centrifuge drive means and rotated to centrifuge each of said samples and separate the same into sample constituent layers, whereupon said tray means are removed as a unit from said centrifuge drive means and operatively associated with automatic sample analysis means for indexing to supply a series of one of said sample constituents from said sample container means to said analysis means. Outer tray means comprising a plurality of outer sample container means are provided for use in conjunction with said tray means for the concomitant supply of, for example, a whole sample and a separated sample constituent to said sample analysis means. For such use, the tray means and outer tray means are combined in predetermined manner which insures ample container means and outer sample container means alignment, and the combined trays indexed as a unit.

    Abstract translation: 公开了新的和改进的样品处理和供应装置,并且包括托盘装置,枢转地支撑多个部分填充的样品容器装置。 在使用中,所述托盘装置可操作地连接到离心机驱动装置并旋转以离心每个所述样品并将其分离成样品构成层,于是所述托盘装置作为一个单元从所述离心机驱动装置移除并可操作地与自动样品 分析装置,用于索引以从所述样品容器装置向所述分析装置供应一系列所述样品成分。 提供包括多个外部样品容器装置的外部托盘装置,用于与所述托盘装置结合使用,以便例如将整个样品和分离的样品成分同时供应到所述样品分析装置。 对于这种用途,托盘装置和外托盘装置以预定的方式组合,这确保了充足的容器装置和外部样品容器装置对齐,并且组合的托盘作为一个单元编入索引。

    Method for preparing smears of biological liquids
    2.
    发明授权
    Method for preparing smears of biological liquids 失效
    制备生物液体涂片的方法

    公开(公告)号:US3871895A

    公开(公告)日:1975-03-18

    申请号:US37529173

    申请日:1973-06-29

    Inventor: ADLER STANFORD L

    CPC classification number: G01N1/2813 Y10T436/110833

    Abstract: Apparatus and method for preparing a smear of a biological fluid substance on a substrate, utilizing a ribbon having relatively small openings in at least one surface thereof which openings are of substantially uniform size and are arranged substantially uniformly both longitudinally and transversely of the ribbon throughout at least a portion of the ribbon. The method includes the steps of supporting the substrate for movement and supporting the ribbon by a support to close proximity to the substrate at a substance-applying station, for a run of the ribbon past a portion of the substrate. Further steps include introducing a relatively small quantity of the aforementioned substance between the aforementioned ribbon surface portion and the substrate at the substance-applying station to spread by capillarity in a direction transversely of the ribbon, and moving the substrate in a direction to smear the substance on the substrate.

    Abstract translation: 用于在衬底上制备生物流体物质的污迹的装置和方法,利用在其至少一个表面中具有相对小的开口的带,其开口具有基本上均匀的尺寸,并且在丝带的纵向和横向基本均匀地布置在整个 色带的至少一部分。 该方法包括以下步骤:支撑用于运动的基底并通过支撑件支撑色带,以在物质施加位置靠近基底,以使色带经过基底的一部分。 进一步的步骤包括在物质施加站之间的上述带状表面部分和基底之间引入相对少量的上述物质,以沿横向于带状物的方向的毛细管扩散,并使基材沿着涂抹物质的方向移动 在基板上。

    Method and apparatus for determining the viscosity of a liquid sample
    3.
    发明授权
    Method and apparatus for determining the viscosity of a liquid sample 失效
    用于测定液体样品粘度的方法和装置

    公开(公告)号:US3861197A

    公开(公告)日:1975-01-21

    申请号:US37522373

    申请日:1973-06-29

    Inventor: ADLER STANFORD L

    CPC classification number: G01N11/14 G01N35/00009 G01N2011/147

    Abstract: Apparatus and method for determining the viscosity of a liquid sample, comprising supporting a quantity of the sample with a surface thereof exposed to the ambient atmosphere, placing a magnetic wafer on the sample surface, for support thereon, generating a rotating magnetic field about the center of the wafer to spin the wafer on its center, and monitoring the rate of rotation of the wafer as an indication of the viscosity of the sample. Further applications include detecting a change in the viscosity of a sample and determinations of Prothrombin Time and Partial Thromboplastin Time of blood specimens, and various other uses where the end point of a reaction in a sample mixture is evidenced by a change of viscosity.

    Abstract translation: 用于确定液体样品的粘度的装置和方法,包括将一定数量的样品暴露于环境大气的表面,将磁性晶片放置在样品表面上,用于支撑在其上,产生围绕中心的旋转磁场 的晶片将晶片旋转在其中心,并且监测晶片的旋转速率作为样品粘度的指示。 其他应用包括检测样品的粘度变化以及血液样品的凝血酶原时间和部分凝血活酶时间的测定以及样品混合物中的反应终点由粘度变化证明的各种其它用途。

    Serum separator and fibrin filter
    4.
    发明授权
    Serum separator and fibrin filter 失效
    血清分离器和纤维蛋白过滤器

    公开(公告)号:US3929646A

    公开(公告)日:1975-12-30

    申请号:US49053974

    申请日:1974-07-22

    Inventor: ADLER STANFORD L

    CPC classification number: B01L3/50215

    Abstract: An article for drawing and holding a blood sample and adapted to be centrifuged to thereby position a separator between the packed cell portion of the blood, the heavier phase, and the serum or plasma portion, the lighter phase. The article includes a rigid evacuated tubular container hermetically sealed with a removable resilient stopper, an inner cover element within the container detachably connected to the stopper to be separated therefrom on centrifugation of the blood sample, the element having plural filter openings therein, and a quantity of an inert semifluid sealant in the bottom of the container, the cover element and the sealant each having a specific gravity greater than the serum or plasma portion but less than the packed cell portion. In centrifuged position, the cover element intimately overlies the sealant and is supported from the wall structure of the container by the sealant, the sealant closing the filter openings and forming with the cover element the separator.

    Abstract translation: 用于抽取和保持血液样品并适于离心的制品,从而将血液,较重相和血清或血浆部分的填充细胞部分之间的隔膜定位在较轻相位上。 该物品包括用可移除的弹性止挡器气密密封的刚性真空管状容器,在容器内可拆卸地连接到塞子上的内盖元件,用于离心血液样品,其中具有多个过滤器开口的元件和数量 的容器底部的惰性半流体密封剂,盖元件和密封剂各自具有大于血清或血浆部分但小于填充细胞部分的比重。 在离心位置,盖元件紧密地覆盖密封剂,并通过密封剂从容器的壁结构支撑,密封剂封闭过滤器开口并与盖元件形成隔板。

    Method and apparatus for controlling the temperature of a tape
    5.
    发明授权
    Method and apparatus for controlling the temperature of a tape 失效
    用于控制胶带温度的方法和装置

    公开(公告)号:US3904369A

    公开(公告)日:1975-09-09

    申请号:US36623673

    申请日:1973-06-01

    CPC classification number: G01N21/8483 Y10T436/110833 Y10T436/12

    Abstract: Method of controlling the temperature of a tape element in a tape run utilizing a tape support element having a surface elongated in the direction of the tape run and for coaction with a surface of the tape element, the tape support surface having a tape-receiving part spaced from a tape delivery part, which method includes controlling the temperature of the tape support surface. The method includes the steps of intimately supporting the tape element by the support element, and introducing a relatively small quantity of a temperature-exchange liquid between the aforementioned elements in proximity to the tape receiving part to spread by capillarity in a thin film toward the tape delivery part. Such spreading of the thin liquid film is enhanced by moving the tape element toward the delivery part of the support.

    Abstract translation: 利用带状支撑元件控制带状元件的温度的方法,所述带支撑元件具有沿带延伸方向延伸的表面并与带元件的表面共同作用,所述带支撑表面具有带接收部分 与带递送部分间隔开,该方法包括控制带支撑表面的温度。 该方法包括以下步骤:通过支撑元件紧密地支撑带状元件,并且在靠近带接收部分的上述元件之间引入相对少量的温度交换液体,以通过薄膜中的毛细管状向胶带扩展 交货部分。 通过将带元件移动到支撑件的输送部分来增强薄液膜的这种扩展。

    Apparatus for photometrically analyzing a droplet of a sample liquid
    6.
    发明授权
    Apparatus for photometrically analyzing a droplet of a sample liquid 失效
    用于光学分析样品液滴的装置

    公开(公告)号:US3734622A

    公开(公告)日:1973-05-22

    申请号:US3734622D

    申请日:1971-11-19

    Inventor: ADLER STANFORD L

    CPC classification number: G01N35/00009 G01N21/86 G01N2035/00534

    Abstract: Method and apparatus for photometrically testing for a constituent of a droplet of a discrete liquid sample having an arcuate surface and having a planar surface resting on or suspended from a surface and wherein light rays from a source are directed into the droplet through the planar surface thereof. Light energy as a measure of absorbance, light scattering or fluorescence is transmitted through the planar droplet surface to a photodetector for analysis of the sample which analysis may be qualitative or quantitative or indicate an end reaction. Such analysis may be automated.

    Abstract translation: 用于对具有弧形表面并具有搁置在表面上或从表面悬挂的平面表面的离散液体样品的液滴的组分进行光度测试的方法和装置,并且其中来自源的光线通过其平面被引导到液滴中 。 作为吸光度,光散射或荧光的量度的光能通过平面液滴表面传输到光电检测器,用于分析样品,该分析可以是定性的或定量的或指示最终反应。 这种分析可以是自动的。

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