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公开(公告)号:CH611028A5
公开(公告)日:1979-05-15
申请号:CH1038076
申请日:1976-08-16
Applicant: TECHNICON INSTR
Inventor: SANDROCK HAROLD E , LEEN MORRIS W , STARK EDWARD W
Abstract: A multichamber cuvette for maintaining in independent and separate condition at least two reactants until such time that it is desired to mix them for reaction with each other and a reactant liquid sample for analysis in the cuvette. There is provided a cuvette body of a suitable plastic defining at least two chambers interconnected by a passageway of relatively small cross section having at least the end portions thereof of capillary size to prevent under many circumstances, as by surface tension, accidental mixture of liquid reactants in the chambers. If there is a substantial head of liquid in one chamber and/or a risk of impact of the cuvette with an external foreign object, sufficient to break such surface tension, an air lock in the passageway when the latter is below the liquid levels in the chambers prevents such accidental mixture. A baffle in the passageway enhances separation of liquids and/or solid substances in the chambers. The chambers are open-topped, and a unitary probe-wiping multi-ply laminated cover of a type puncturable by a probe extends over the chambers closing them from the external environment. The laminated cover tends to be self-closing with reference to such punctures. One ply is of metal foil to act as a vapor seal and has an undercoating of a heat sealable material compatible with the body material and sealed thereto. The top ply is of a moisture-absorbent material which is secured to the foil ply by an intermediate plastic ply.
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公开(公告)号:AU5041279A
公开(公告)日:1980-02-28
申请号:AU5041279
申请日:1979-08-29
Applicant: TECHNICON INSTR
Inventor: SANDROCK HAROLD E , LEEN MORRIS W , STARK EDWARD W
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公开(公告)号:CA1063830A
公开(公告)日:1979-10-09
申请号:CA314735
申请日:1978-10-30
Applicant: TECHNICON INSTR
Inventor: SANDROCK HAROLD E , STARK EDWARD W , GYORI STEVEN A
Abstract: Apparatus and method for photometrically analyzing a constituent of interest in body or other fluids and well suited for kinetic determinations which are temperature-and-time dependent. There is provided a sample holder holding a cuvette supporting a liquid sample and other reactants among which is a trigger reactant to initiate the reaction which is analyzed. The trigger and the other reactants are initially isolated in the cuvette. The holder, one of a series, is moved periodically to move the cuvette, one of a series handled sequentially, to a temperature-sensing and preheated station, to a station wherein the contents of the cuvette are mixed to enable the reaction to proceed, to an optical station where the reaction is viewed for an optical density determination over a period of time under temperature conditions regulated within limits, and to a station for sensing the temperature of the mixture, by immersion of a temperature sensor therein, and supplying data for estimation of the real temperature during the optical determination for inclusion in the determination of the concentration of the constituent of interest, all in a relatively short period of time.
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公开(公告)号:CA1070139A
公开(公告)日:1980-01-22
申请号:CA315146
申请日:1978-10-31
Applicant: TECHNICON INSTR
Inventor: SANDROCK HAROLD E , LEEN MORRIS W , STARK EDWARD W
Abstract: A multichamber cuvette for maintaining in independent and separate condition at least two reactants until such time that it is desired to mix them for reaction with each other and a reactant liquid sample while in the cuvette for analysis in the cuvette, and a method of use of such cuvette. There is provided a cuvette body of a suitable plastic defining at least two chambers interconnected by a passageway of relatively small cross-section having at least the end portion thereof of capillary size to prevent under many circumstances, as by surface tension accidental mixture of liquid reactants in the chambers. If there is a substantial head of liquid in one chamber and/or a risk of impact of the cuvette with an external foreign object, sufficient to break such surface tension, an air lock in the passageway when the latter is below the liquid levels in the chambers prevents such accidental mixture. A baffle in the passageway enhances separation of liquids and/or solid substances in the chambers. The chambers are opentopped, and a unitary probe-wiping multi-ply laminated cover of a type puncturable by a probe extends over the chambers closing them from the external environment. The laminated cover tends to be self-closing with reference to such punctures. One ply is of metal foil to act as a vapor seal and has an undercoating of a heat sealable material compatible with the body material and sealed thereto. The top ply is of a moisture-absorbent material which is secured to the foil ply by an intermediate plastic ply.
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公开(公告)号:CA1070137A
公开(公告)日:1980-01-22
申请号:CA314736
申请日:1978-10-30
Applicant: TECHNICON INSTR
Inventor: SANDROCK HAROLD E , STARK EDWARD W , GYORI STEVEN A
Abstract: Apparatus and method for photometrically analyzing a constituent of interest in body or other fluids and well suited for kinetic determinations which are temperature-and-time dependent. There is provided a sample holder holding a cuvette supporting a liquid sample and other reactants among which is a trigger reactant to initiate the reaction which is analyzed. The trigger and the other reactants are initially isolated in the cuvette. The holder, one of a series, is moved periodically to move the cuvette, one of a series handled sequentially, to a temperature-sensing and preheating station, to a station where the contents of the-cuvette are mixed to enable the reaction to proceed, to an optical station where the reaction is viewed for an optical density determination over a period of time under temperature conditions regulated within limits, and to a station for sensing the temperature of the mixture, by immersion of a temperature sensor therein, and supplying data for estimation of the real temperature during the optical determination for inclusion in the determination of the concentration of the constituent of interest, all in a relatively short period of time.
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公开(公告)号:CA1057974A
公开(公告)日:1979-07-10
申请号:CA257811
申请日:1976-07-26
Applicant: TECHNICON INSTR
Inventor: SANDROCK HAROLD E , STARK EDWARD W , GYORI STEVEN A
Abstract: Apparatus and method for photometrically analyzing a constituent of interest in body or other fluids and well suited for kinetic determinations which are temperature-and-time dependent. There is provided a sample holder holding a cuvette supporting a liquid sample and other reactants among which is a trigger reactant to initiate the reaction which is analyzed. The trigger and the other reactants are initially isolated in the cuvette. The holder, one of a series, is moved periodically to move the cuvette, one of a series handled sequentially, to a temperature-sensing and preheating station, to a station where the contents of the cuvette are mixed to enable the reaction to proceed, to an optical station where the reaction is viewed for and optical density determination over a period of time under temperature conditions regulated within limits, and to a station for sensing the temperature of the mixture, by immersion of a temperature sensor therein, and supplying data for estimation of the real temperature during the optical determination for inclusion in the determination of the concentration of the constituent of interest, all in a relatively short period of time.
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公开(公告)号:CA1023803A
公开(公告)日:1978-01-03
申请号:CA226103
申请日:1975-05-02
Applicant: TECHNICON INSTR
Inventor: MADER ARTHUR H , GASIUNAS DONATAS V , STARK EDWARD W
Abstract: New and improved apparatus is provided for the calibration and standardization of the analog output signal level of automated analysis equipment, which level varies as a function of the concentration of the constituent being analyzed. Such apparatus comprises an A/D converter including a dual-slope integrator for translating the output signal level to a time interval which varies as a function of the constituent. Such apparatus further includes means for generating the inverse function of the analytical function, which is applied to linearize and scale the output signal level and to convert such level directly to digital form. Also, provision is made for the calibration and standardization, on an individual basis, of each of a plurality of analytical channels in a multi-channel system.
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公开(公告)号:CA1237927A
公开(公告)日:1988-06-14
申请号:CA445870
申请日:1984-01-23
Applicant: TECHNICON INSTR
Inventor: STARK EDWARD W
Abstract: NEW AND IMPROVED LENS MEANS FOR USE IN RADIATION ENERGY INTEGRATING SPHERES Lens means for utilization in the radiation energy exit port of a radiation energy integrating sphere are provided, and function to prevent instrumental specular radiation energy reflections from striking the interior wall surfaces of the sphere and being collected thereby. The instrumental specular radiation energy reflections include those from the lens means, per se, and those from instrumentation disposed without the integrating sphere.
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公开(公告)号:CA1079540A
公开(公告)日:1980-06-17
申请号:CA257169
申请日:1976-07-16
Applicant: TECHNICON INSTR
Inventor: SANDROCK HAROLD E , LEEN MORRIS W , STARK EDWARD W
Abstract: A multichamber cuvette for maintaining in independent and separate condition at least two reactants until such time that it is desired to mix them for reaction with each other and a reactant liquid sample while in the cuvette for analysis in the cuvette, and a method of use of such cuvette. There is provided a cuvette body of a suitable plastic defining at least two chambers interconnected by a passageway of relatively small cross section having at least the end portion thereof of capillary size to prevent under many circumstances, as by surface tension, accidental mixture of liquid reactants in the chambers. If there is a substantial head of liquid in one foreign object, sufficient to break such surface tension, an air lock in the passageway when the latter is below the liquid levels in the chambers prevents such accidental mixture. A baffle in the passageway enhances separation of liquids and/or solid substances in the chambers. The chambers are open-topped, and a unitary probe-wiping multi-ply laminated cover of a type puncturable by a probe extends over the chambers closing them from the external environment. The laminated cover tends to be self-closing with reference to such punctures. One ply is of metal foil to act as a vapor seal and has an undercoating of a heat sealable material compatible with the body material and sealed thereto. The top ply is of a moisture-absorbent material which is secured to the foil ply by an intermediate plastic ply.
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公开(公告)号:AU5041379A
公开(公告)日:1980-01-03
申请号:AU5041379
申请日:1979-08-29
Applicant: TECHNICON INSTR
Inventor: SANDROCK HAROLD E , LEEN MORRIS W , STARK EDWARD W
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