公开(公告)号：WO1995030427A1

公开(公告)日：1995-11-16

申请号：PCT/US1995005459

申请日：1995-05-03

Applicant: THE BOARD OF REGENTS OF OKLAHOMA STATE UNIVERSITY

Inventor： THE BOARD OF REGENTS OF OKLAHOMA STATE UNIVERSITY ,  CHENG, Nan-Zheng ,  STOECKER, Barbara, J.

IPC: A61K35/78

CPC classification number: A61K36/70 ,  Y10S514/866

Abstract: A composition and method for treating hyperglycemia which utilize an extract of the Chinese herb Polygonum multiflorum. The herb is extracted with 0.1 N NH4OH and centrifuged. The supernatant is applied to a Sephadex G-25 column. Three fractions are collected. The fractions exhibit a high insulin potentiating activity in fat cell assays and are shown to lower blood glucose levels.

Abstract translation: 一种治疗高血糖症的组合物和方法，其利用中草药枸杞提取物。 草本植物用0.1N NH4OH提取，离心。 将上清液施加到Sephadex G-25柱上。 收集三个分数。 这些级分在脂肪细胞测定中显示出高的胰岛素增强活性，并且显示降低血糖水平。