公开(公告)号：WO1994007899A1

公开(公告)日：1994-04-14

申请号：PCT/US1993009037

申请日：1993-09-23

Applicant: THE BOARD OF REGENTS acting for and on behalf of ...

Inventor： THE BOARD OF REGENTS acting for and on behalf of ... ,  KOREEDA, Masato ,  HOUSTON, Todd, A.

IPC: C07H01/00

CPC classification number: C07D307/32 ,  C07D309/30

Abstract: The invention concerns C-glycosylated derivatives of soft carbon nucleophile compounds, particularly compounds which contain acid-labile structural units. The invention further concerns a mild, cost-effective, non-hazardous and stereoselective method of general application employing a glycal as a glycosylating agent and iodine as a catalyst for the preparation of C-glycosylated soft carbon nucleophile compounds.

Abstract translation: 本发明涉及软碳亲核试剂化合物的C-糖基化衍生物，特别是含酸不稳定结构单元的化合物。 本发明还涉及使用甘氨酸作为糖基化剂和碘作为制备C-糖基化的软碳亲核化合物的催化剂的一般应用的温和的，具有成本效益的非危险和立体选择性方法。