公开(公告)号：EP1856492A2

公开(公告)日：2007-11-21

申请号：EP06717941.6

申请日：2006-01-11

Applicant: THE CURATORS OF THE UNIVERSITY OF MISSOURI

Inventor： LARSEN, David W. ,  XU, Zhi

IPC: G01J3/42 ,  G01J3/427

CPC classification number: G01N21/31 ,  G01J3/02 ,  G01J3/0224 ,  G01J3/0262 ,  G01J3/0286 ,  G01J3/0291 ,  G01J3/42 ,  G01J2003/425 ,  G01N21/274 ,  G01N2021/3137 ,  G01N2201/0227 ,  G01N2201/0642 ,  G01N2201/127

Abstract: The invention concerns spectrophotometer devices that provide for ultrasensitive measurements through a reflection interaction with matter. Embodiments of the invention use sealed housings (112, 600, 700) lacking an internal light source, and reflection based sample and reference cells. In some embodiments a substantially solid thermally conductive housing (600, 700) is used. Oilier features of preferred embodiments include particular reflection based sample and reference cells. A total internal reflection embodiment includes a prism (302, 322, 622a, 623a) including an interaction surface, a detector, a lens that focuses a beam output from the prism onto the detector, and a closed interaction volume having an inlet and an outlet for delivering gas or liquid to the interaction surface. In a specular reflection embodiment, a reflective surface (402, 422) is used. In a diffuse reflection embodiment a matte surface (502, 522) is used and the matte surface produces scattering.