公开(公告)号：WO2017112941A1

公开(公告)日：2017-06-29

申请号：PCT/US2016/068547

申请日：2016-12-23

Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

Inventor： LAL, Ratneshwar ,  HWANG, Michael, Taeyoung ,  LANDON, Preston, Boone ,  GLINSKII, Gennadi, V. ,  MO, Alexander ,  RAMACHANDRAN, Srinivasan ,  LEE, Joon ,  MECKES, Brian

IPC: B82Y15/00 ,  C07H21/02 ,  C12N15/09 ,  C12Q1/68 ,  G01N27/00 ,  G01N27/04

CPC classification number: B82Y15/00 ,  C12Q1/68 ,  C12Q1/6816 ,  G01N27/00 ,  C12Q2563/107 ,  C12Q2565/525 ,  C12Q2565/607 ,  C12Q2565/625

Abstract: Methods, systems, and nano-sensor devices are disclosed for detecting or discriminating nucleic acids with a single nucleotide resolution based on nucleic acid strand displacement. The detection can be made by time-lapse fluorescence measurements or by electro-based graphene FET, which can be combined with wireless communication to provide real-time transmission of the detected signals.

Abstract translation: 公开了基于核酸链置换以单核苷酸分辨率检测或区分核酸的方法，系统和纳米传感器装置。 可以通过延时荧光测量或通过基于电子的石墨烯FET来进行检测，其可以与无线通信结合以提供检测到的信号的实时传输。

公开(公告)号：EP3402745A1

公开(公告)日：2018-11-21

申请号：EP16880152.0

申请日：2016-12-23

Applicant: The Regents of the University of California

Inventor： LAL, Ratneshwar ,  HWANG, Michael, Taeyoung ,  LANDON, Preston, Boone ,  GLINSKII, Gennadi, V. ,  MO, Alexander ,  RAMACHANDRAN, Srinivasan ,  LEE, Joon ,  MECKES, Brian

IPC: B82Y15/00 ,  C07H21/02 ,  C12N15/09 ,  C12Q1/68 ,  G01N27/00 ,  G01N27/04

CPC classification number: B82Y15/00 ,  C12Q1/68 ,  C12Q1/6816 ,  G01N27/00 ,  C12Q2563/107 ,  C12Q2565/525 ,  C12Q2565/607 ,  C12Q2565/625

Abstract: Methods, systems, and nano-sensor devices are disclosed for detecting or discriminating nucleic acids with a single nucleotide resolution based on nucleic acid strand displacement. The detection can be made by time-lapse fluorescence measurements or by electro-based graphene FET, which can be combined with wireless communication to provide real-time transmission of the detected signals.