公开(公告)号：US20190234911A1

公开(公告)日：2019-08-01

申请号：US16337339

申请日：2017-09-28

Applicant: THE REGENTS OF THE UNIVERSITY OF COLORADO A BODY CORPORATE

Inventor： Todd W. Murray ,  Peter Burgholzer ,  Markus Haltmeier

IPC: G01N29/44 ,  G01N29/24

CPC classification number: G01N29/4472 ,  G01N21/1702 ,  G01N21/4795 ,  G01N29/00 ,  G01N29/0672 ,  G01N29/2418 ,  G01N2021/1706 ,  G01N2021/479 ,  G01N2021/8444 ,  G01N2201/106

Abstract: A method for high resolution photoacoustic imaging in scattering media using structured illumination may include illuminating a sample of an absorption object with structured illumination, including illuminating the sample with multiple different speckle patterns at different times. The method may also include detecting multiple photoacoustic signals generated by the absorption object in response to illumination with the different speckle patterns to generate multiple photoacoustic responses. The method may also include reconstructing an absorber distribution of the absorption object by exploiting joint sparsity of sound sources in the plurality of photoacoustic responses.