公开(公告)号：US09056159B2

公开(公告)日：2015-06-16

申请号：US13916715

申请日：2013-06-13

Applicant: THORATEC CORPORATION

Inventor： Alexander Medvedev ,  Muhammad K. Sami ,  Masamichi Yanai

IPC: A61N1/362 ,  A61M1/10 ,  A61M1/12

CPC classification number: A61M1/1086 ,  A61M1/1005 ,  A61M1/101 ,  A61M1/122 ,  A61M2205/3334 ,  A61M2205/3365

Abstract: A circulatory assist system has a pump with a motor coupled to rotate the pump at a selectable speed. A controller drives the motor at a target speed and collects blood flow measurements during operation of the pump. An impaired flow condition is identified when a plurality of successive blood flow measurements are between an expected minimum flow and a low flow threshold, such that the low flow would necessitate issuing an alert. During the impaired flow condition, it is detected whether an inflow obstruction exists by determining whether a reduction in speed of the pump is correlated with a predetermined increase in the blood flow measurements. If the inflow obstruction is detected, then the speed of the pump is further reduced to further increase the blood flow measurements.

Abstract translation: 循环辅助系统具有泵，其具有马达耦合以以可选择的速度旋转泵。 控制器以目标速度驱动电机，并在泵的运行期间收集血流测量值。 当多个连续血流测量在预期的最小流量和低流量阈值之间时，识别受损的流动状况，使得低流量将需要发出警报。 在受损的流动条件下，通过确定泵的速度降低是否与血流测量的预定增加相关联来检测是否存在流入阻塞物。 如果检测到流入阻塞，则泵的速度进一步降低，以进一步增加血液流量测量值。

公开(公告)号：US20140323796A1

公开(公告)日：2014-10-30

申请号：US13873551

申请日：2013-04-30

Applicant: THORATEC CORPORATION

Inventor： Alexander Medvedev ,  Masamichi Yanai

IPC: A61M1/10

CPC classification number: A61M1/1086 ,  A61M1/1005 ,  A61M1/101 ,  A61M1/122 ,  A61M2205/3334

Abstract: A blood pump system is implantable in a patient for ventricular support. A pumping chamber has an inlet for receiving blood from a ventricle of the patient. An impeller is received in the pumping chamber. A motor is coupled to the impeller for driving rotation of the impeller. A motor controller is provided for tracking systolic and diastolic phases of a cardiac cycle of the patient and supplying a variable voltage signal to the motor in a variable speed mode to produce a variable impeller speed linked to the cardiac cycle. The impeller speed comprises a ramping up to an elevated speed during the diastolic phase in order to reduce a load on the ventricle at the beginning of the systolic phase.

Abstract translation: 血液泵系统可植入患者的心室支持。 抽吸室具有用于从患者的心室接收血液的入口。 在泵送室中接收叶轮。 电动机联接到叶轮以驱动叶轮的旋转。 提供电动机控制器用于跟踪患者心脏周期的收缩期和舒张期，并以可变速度模式向电动机提供可变电压信号，以产生与心动周期相关的可变叶轮速度。 叶轮速度包括在舒张期期间升高至升高的速度，以便在心脏收缩期开始时减少心室负荷。

公开(公告)号：US20160228628A1

公开(公告)日：2016-08-11

申请号：US15041716

申请日：2016-02-11

Applicant: Thoratec Corporation

Inventor： Alexander Medvedev ,  Shunzhou Yu ,  Ren You

IPC: A61M1/10 ,  A61M1/12

CPC classification number: A61M1/1086 ,  A61M1/1005 ,  A61M1/101 ,  A61M1/1046 ,  A61M1/122 ,  A61M2205/3334

Abstract: A method for synchronizing operation of a heart assist pump device to a patient's cardiac cycle includes obtaining a signal from a motor of a heart assist pump device and filtering the signal to remove noise. The method also includes determining a speed synchronization start point at which time the motor of the heart assist pump device will begin a change in speed of operation based on the filtered signal. The method further includes modulating a speed of the motor of the heart assist pump device to a target speed at the speed synchronization start point, thereby synchronizing the change in speed of operation with a patient's cardiac cycle.

Abstract translation: 一种用于将心脏辅助泵装置的操作与患者的心动周期同步的方法包括从心脏辅助泵装置的电动机获得信号并对信号进行滤波以去除噪声。 该方法还包括确定速度同步起始点，此时基于滤波信号，心脏辅助泵装置的马达将开始运行速度的改变。 该方法还包括将心脏辅助泵装置的马达的速度调制到速度同步起始点处的目标速度，从而使运行速度的变化与患者的心动周期同步。

公开(公告)号：US20160058930A1

公开(公告)日：2016-03-03

申请号：US14834771

申请日：2015-08-25

Applicant: Thoratec Corporation

Inventor： Alexander Medvedev ,  J. Bradford Rainier ,  Muhammad K. Sami

IPC: A61M1/10

CPC classification number: A61M1/1086 ,  A61M1/101 ,  A61M1/1017 ,  A61M1/1031 ,  A61M1/122 ,  A61M2205/3334 ,  A61M2205/3365 ,  A61M2205/50

Abstract: A system and method for detecting and mitigating a suction condition are disclosed. The method may include characterizing pump waveform signal, identifying and evaluating a characteristic of the waveform for an existence of a suction condition. In various embodiments, a change in harmonic spectral distribution will identify a probability of a suction condition. A speed of the pump may be adjusted to mitigate the suction condition.

Abstract translation: 公开了一种用于检测和减轻吸入条件的系统和方法。 该方法可以包括表征泵浦波形信号，识别和评估波形的存在吸入条件的特性。 在各种实施例中，谐波频谱分布的变化将识别抽吸条件的概率。 可以调节泵的速度以减轻吸入条件。

公开(公告)号：US20160058929A1

公开(公告)日：2016-03-03

申请号：US14834757

申请日：2015-08-25

Applicant: Thoratec Corporation

Inventor： Alexander Medvedev ,  J. Bradford Rainier ,  Muhammad K. Sami

IPC: A61M1/10

CPC classification number: A61M1/1086 ,  A61M1/101 ,  A61M1/1017 ,  A61M1/1031 ,  A61M1/122 ,  A61M2205/3334 ,  A61M2205/50

Abstract: A system and method for detecting and mitigating a suction condition are disclosed. The method may include estimating a flow waveform of the pump, identifying pulses in the flow waveform, determining a negative flow based on a valid identification of a pulse, and evaluating a characteristic of the pulse for an existence of a suction condition. In various embodiments, a suction marker is located based on a minimum in a diastolic phase, and the suction marker location is used to identify a probability of a suction condition. A speed of the pump may be adjusted to mitigate the suction condition. A system and method for estimating flow is further disclosed. The method may include interpolating data sets defining pump power to flow for various pump speed values.

Abstract translation: 公开了一种用于检测和减轻吸入条件的系统和方法。 该方法可以包括估计泵的流量波形，识别流量波形中的脉冲，基于脉冲的有效识别确定负流，以及评估脉冲的存在吸入条件的特性。 在各种实施例中，基于舒张期中的最小值来定位吸引标记，并且使用吸引标记位置来识别抽吸条件的概率。 可以调节泵的速度以减轻吸入条件。 进一步公开了一种用于估计流量的系统和方法。 该方法可以包括内插定义泵功率以便各种泵速度值流动的数据集。

公开(公告)号：US20160235899A1

公开(公告)日：2016-08-18

申请号：US15042431

申请日：2016-02-12

Applicant: Thoratec Corporation

Inventor： Shunzhou Yu ,  Alexander Medvedev ,  Ren You

IPC: A61M1/10

CPC classification number: A61M1/1015 ,  A61M1/101 ,  A61M1/1012 ,  A61M1/1013 ,  A61M1/1017 ,  A61M1/1031 ,  A61M1/1086 ,  A61M1/122 ,  A61M2205/3306 ,  A61M2205/3317 ,  A61M2205/3334

Abstract: A rotary machine is provided which may include a rotor and a stator within a housing. The stator may be for generating a rotating magnetic field for applying a torque to the rotor. A commutator circuit may provide a plurality of phase voltages to the stator, and a controller may adjust the plurality of phase voltages provided by the commutator circuit to modify an attractive force of the stator on the rotor to move the rotor in an axial direction.

Abstract translation: 提供了一种旋转机器，其可以在壳体内包括转子和定子。 定子可以用于产生用于向转子施加扭矩的旋转磁场。 换向器电路可以向定子提供多个相电压，并且控制器可以调整由换向器电路提供的多个相电压，以改变定子在转子上的吸引力，从而沿轴向方向移动转子。