公开(公告)号：US20160235898A1

公开(公告)日：2016-08-18

申请号：US15041987

申请日：2016-02-11

Applicant: Thoratec Corporation

Inventor： Masamichi Yanai ,  Shunzhou Yu ,  Tao Zhang

IPC: A61M1/10 ,  F04D13/06 ,  F04D1/00

CPC classification number: A61M1/1029 ,  A61M1/101 ,  A61M1/1012 ,  A61M1/1013 ,  A61M1/1015 ,  A61M1/1017 ,  A61M1/1031 ,  A61M1/1086 ,  A61M1/122 ,  A61M2205/3334 ,  F04D13/064 ,  F04D13/0666 ,  F04D29/047 ,  F04D29/048

Abstract: A blood pump system includes a pump housing and an impeller for rotating in a pump chamber within the housing. The impeller has a first side and a second side opposite the first side. The system includes a stator having drive coils for applying a torque to the impeller and at least one bearing mechanism for suspending the impeller within the pump chamber. The system includes a position control mechanism for moving the impeller in an axial direction within the pump chamber to adjust a size of a first gap and a size of a second gap, thereby controlling a washout rate at each of the first gap and the second gap. The first gap is defined by a distance between the first side and the housing and the second gap is defined by a distance between the second side and the pump housing.

Abstract translation: 血液泵系统包括泵壳体和用于在壳体内的泵室中旋转的叶轮。 叶轮具有与第一侧相对的第一侧和第二侧。 该系统包括具有用于向叶轮施加扭矩的驱动线圈和用于将叶轮悬挂在泵室内的至少一个轴承机构的定子。 该系统包括位置控制机构，用于在泵室内沿轴向移动叶轮以调节第一间隙的尺寸和第二间隙的尺寸，从而控制第一间隙和第二间隙中的每一个处的冲洗速率 。 第一间隙由第一侧和壳体之间的距离限定，第二间隙由第二侧和泵壳之间的距离限定。

公开(公告)号：US09056159B2

公开(公告)日：2015-06-16

申请号：US13916715

申请日：2013-06-13

Applicant: THORATEC CORPORATION

Inventor： Alexander Medvedev ,  Muhammad K. Sami ,  Masamichi Yanai

IPC: A61N1/362 ,  A61M1/10 ,  A61M1/12

CPC classification number: A61M1/1086 ,  A61M1/1005 ,  A61M1/101 ,  A61M1/122 ,  A61M2205/3334 ,  A61M2205/3365

Abstract: A circulatory assist system has a pump with a motor coupled to rotate the pump at a selectable speed. A controller drives the motor at a target speed and collects blood flow measurements during operation of the pump. An impaired flow condition is identified when a plurality of successive blood flow measurements are between an expected minimum flow and a low flow threshold, such that the low flow would necessitate issuing an alert. During the impaired flow condition, it is detected whether an inflow obstruction exists by determining whether a reduction in speed of the pump is correlated with a predetermined increase in the blood flow measurements. If the inflow obstruction is detected, then the speed of the pump is further reduced to further increase the blood flow measurements.

Abstract translation: 循环辅助系统具有泵，其具有马达耦合以以可选择的速度旋转泵。 控制器以目标速度驱动电机，并在泵的运行期间收集血流测量值。 当多个连续血流测量在预期的最小流量和低流量阈值之间时，识别受损的流动状况，使得低流量将需要发出警报。 在受损的流动条件下，通过确定泵的速度降低是否与血流测量的预定增加相关联来检测是否存在流入阻塞物。 如果检测到流入阻塞，则泵的速度进一步降低，以进一步增加血液流量测量值。

公开(公告)号：US08968174B2

公开(公告)日：2015-03-03

申请号：US13742469

申请日：2013-01-16

Applicant: Thoratec Corporation

Inventor： Masamichi Yanai ,  Tao Zhang

IPC: A61M1/12 ,  A61M1/10

CPC classification number: A61M1/1086 ,  A61M1/101 ,  A61M1/122 ,  A61M1/127 ,  A61M2205/17

Abstract: A implantable pump system comprises an implantable pump motor and an external unit. An inverter comprises respective phases couple to the motor via a cable with redundant conductors for each phase. A controller receives power measurements for all the redundant conductors, which are combined and compared in order to detect failures in the non-redundant components within the motor and windings.

Abstract translation: 可植入泵系统包括可植入泵电动机和外部单元。 逆变器包括通过具有用于每个相的冗余导线的电缆耦合到电动机的各相。 控制器接收所有冗余导体的功率测量值，这些导线被组合和比较，以便检测电机和绕组内非冗余组件的故障。

公开(公告)号：US20140323796A1

公开(公告)日：2014-10-30

申请号：US13873551

申请日：2013-04-30

Applicant: THORATEC CORPORATION

Inventor： Alexander Medvedev ,  Masamichi Yanai

IPC: A61M1/10

CPC classification number: A61M1/1086 ,  A61M1/1005 ,  A61M1/101 ,  A61M1/122 ,  A61M2205/3334

Abstract: A blood pump system is implantable in a patient for ventricular support. A pumping chamber has an inlet for receiving blood from a ventricle of the patient. An impeller is received in the pumping chamber. A motor is coupled to the impeller for driving rotation of the impeller. A motor controller is provided for tracking systolic and diastolic phases of a cardiac cycle of the patient and supplying a variable voltage signal to the motor in a variable speed mode to produce a variable impeller speed linked to the cardiac cycle. The impeller speed comprises a ramping up to an elevated speed during the diastolic phase in order to reduce a load on the ventricle at the beginning of the systolic phase.

Abstract translation: 血液泵系统可植入患者的心室支持。 抽吸室具有用于从患者的心室接收血液的入口。 在泵送室中接收叶轮。 电动机联接到叶轮以驱动叶轮的旋转。 提供电动机控制器用于跟踪患者心脏周期的收缩期和舒张期，并以可变速度模式向电动机提供可变电压信号，以产生与心动周期相关的可变叶轮速度。 叶轮速度包括在舒张期期间升高至升高的速度，以便在心脏收缩期开始时减少心室负荷。

公开(公告)号：US20140309481A1

公开(公告)日：2014-10-16

申请号：US13860569

申请日：2013-04-11

Applicant: THORATEC CORPORATION

Inventor： Alexander L. Medvedev ,  Masamichi Yanai

IPC: A61M1/10

CPC classification number: A61M1/1013 ,  A61M1/101 ,  A61M1/1015 ,  A61M1/1017 ,  A61M1/1031 ,  A61M1/122 ,  F04D13/0606 ,  F04D29/047 ,  F04D29/048

Abstract: A rotary blood pump comprises an impeller in a pump housing with a pumping chamber between first and second walls. The impeller operates in a levitated position spaced from the first and second walls in response to hydrodynamic forces which are boosted by hydrodynamic bearing features in the walls. At least one of the impeller or the walls includes at least one mechanical thrust bearing extending between the impeller and each of the walls, wherein the mechanical thrust bearing is configured such that when the impeller is not being held in the levitated position by the hydrodynamic forces then the mechanical thrust bearing is engaged to maintain a predetermined separation between the hydrodynamic bearing features and the impeller. The mechanical thrust bearing is configured such that when the impeller is being held in the levitated position by the hydrodynamic forces then the mechanical thrust bearing is unengaged.

Abstract translation: 旋转式血液泵包括在泵壳体中的具有在第一和第二壁之间的泵送室的叶轮。 叶轮响应于通过壁中的流体动力轴承特征增强的流体动力而工作在与第一和第二壁间隔开的悬浮位置。 叶轮或壁中的至少一个包括在叶轮和每个壁之间延伸的至少一个机械推力轴承，其中机械推力轴承构造成使得当叶轮未被流体动力力保持在悬浮位置时 那么机械推力轴承接合以保持流体动力轴承特征和叶轮之间的预定间隔。 机械推力轴承构造成使得当叶轮通过流体动力力保持在悬浮位置时，机械推力轴承未被接合。

公开(公告)号：US20140288352A1

公开(公告)日：2014-09-25

申请号：US13849704

申请日：2013-03-25

Applicant: THORATEC CORPORATION

Inventor： Masamichi Yanai ,  Himanshu K. Bhatt

IPC: A61M1/12

CPC classification number: A61M1/122 ,  A61M1/101 ,  A61M1/127

Abstract: A blood pump system for left ventricle assist has an implantable pump unit having a multiphase stator having a plurality of windings connected between respective junctions for forming first, second, and third phases. An external control unit comprises an H-bridge inverter having first, second, and third phase legs. A percutaneous cable is provided having first, second, and third parallel pairs of redundant conductors. Each conductor pair is connected between a respective phase leg and a respective junction. The conductors are arranged concentrically around a cable core so that individual conductors of each pair are separated by at least one conductor of a different conductor pair.

Abstract translation: 用于左心室辅助的血液泵系统具有可植入泵单元，其具有多相定子，该多相定子具有连接在各个结之间的多个绕组，用于形成第一相，第二相和第三相。 外部控制单元包括具有第一，第二和第三相支腿的H桥逆变器。 提供具有第一，第二和第三平行对冗余导体的经皮电缆。 每个导体对连接在相应的相位支路和相应的连接点之间。 导体围绕电缆芯同心地布置，使得每一对的各个导体由不同导体对的至少一个导体隔开。

公开(公告)号：US20140200389A1

公开(公告)日：2014-07-17

申请号：US13742469

申请日：2013-01-16

Applicant: THORATEC CORPORATION

Inventor： Masamichi Yanai ,  Tao Zhang

IPC: A61M1/10

CPC classification number: A61M1/1086 ,  A61M1/101 ,  A61M1/122 ,  A61M1/127 ,  A61M2205/17

Abstract: A implantable pump system comprises an implantable pump motor and an external unit. An inverter comprises respective phases couple to the motor via a cable with redundant conductors for each phase. A controller receives power measurements for all the redundant conductors, which are combined and compared in order to detect failures in the non-redundant components within the motor and windings.

Abstract translation: 可植入泵系统包括可植入泵电动机和外部单元。 逆变器包括通过具有用于每个相的冗余导线的电缆耦合到电动机的各相。 控制器接收所有冗余导体的功率测量值，这些导线被组合和比较，以便检测电机和绕组内非冗余组件的故障。

公开(公告)号：US08834345B2

公开(公告)日：2014-09-16

申请号：US13742478

申请日：2013-01-16

Applicant: Thoratec Corporation

Inventor： Masamichi Yanai ,  Tao Zhang ,  Jeffrey G. Houdek

IPC: A61M1/10

CPC classification number: A61M1/101 ,  A61M1/1012 ,  A61M1/1086 ,  A61M1/122 ,  A61M2205/3334 ,  F04D15/0088 ,  F04D29/428 ,  F05D2270/335

Abstract: A centrifugal pump system for a cardiac assist device employs a disc-shaped impeller having an outer circumference adapted to be rotatably driven in a pumping direction. A pump housing has a pumping chamber receiving the impeller, wherein the pumping chamber defines an outlet volute having a separation edge spaced from the outer circumference to provide a limited backflow path coinciding with the pumping direction. A motor drives the impeller in response to a voltage provided to the motor. A current sensor measures current flow within the motor in response to the voltage. A controller estimates a pump flow rate in response to a predetermined relation between the measured current and the pump flow rate, wherein the predetermined relation includes a positive slope from a predetermined backflow rate to a zero pump flow rate.

Abstract translation: 用于心脏辅助装置的离心泵系统采用圆盘形叶轮，其具有适于沿泵送方向可旋转地驱动的外周。 泵壳体具有容纳叶轮的泵送室，其中泵送室限定具有与外圆周间隔开的分离边缘的出口蜗壳，以提供与泵送方向一致的有限的回流路径。 电机根据提供给电机的电压来驱动叶轮。 电流传感器响应于电压来测量电动机内的电流。 控制器响应于测量的电流和泵流量之间的预定关系来估计泵流量，其中预定关系包括从预定回流速率到零泵流量的正斜率。

公开(公告)号：US20140243970A1

公开(公告)日：2014-08-28

申请号：US13775622

申请日：2013-02-25

Applicant: THORATEC CORPORATION

Inventor： Masamichi Yanai

IPC: A61M1/10

CPC classification number: A61M1/1086 ,  A61M1/101 ,  A61M1/122 ,  A61M2205/17 ,  A61M2205/3576 ,  A61M2205/52

Abstract: Upon failure of a primary control unit for controlling an implanted pump in a ventricle assist system enhancing blood flow in a patient, an initial backup control unit is substituted for the failed unit. An interface device is connected to one of the initial backup control unit or the primary control unit. Patient-unique data is downloaded to the interface device to create a transfer data set. The initial backup control unit is connected to the implanted pump as a new primary control unit. The interface device is connected to a replacement backup control unit. The transfer data set is uploaded from the interface device to the replacement backup control unit. The transfer data set on the interface device is modified after uploading to prevent a subsequent uploading from the interface device to another control unit.

Abstract translation: 一旦主控制单元在控制增强患者血液流动的心室辅助系统中的植入泵的故障的情况下，则替换故障单元的初始后备控制单元。 接口设备连接到初始备份控制单元或主控制单元之一。 将患者唯一数据下载到接口设备以创建传输数据集。 初始备用控制单元作为新的主控单元连接到植入式泵。 接口设备连接到替换备份控制单元。 传输数据集从接口设备上传到更换备份控制单元。 接口设备上的传输数据在上传后被修改，以防止从接口设备到另一个控制单元的后续上传。

公开(公告)号：US20160281720A1

公开(公告)日：2016-09-29

申请号：US15172760

申请日：2016-06-03

Applicant: Thoratec Corporation

Inventor： Masamichi Yanai ,  Jeffrey H. Campau ,  Jason C. Nanna

IPC: F04D15/00 ,  F04D7/04 ,  F04D29/22 ,  A61M1/12 ,  F04D29/048 ,  F04D29/42 ,  A61M1/10 ,  F04D13/02 ,  F04D29/047

CPC classification number: F04D15/0094 ,  A61M1/101 ,  A61M1/1012 ,  A61M1/1015 ,  A61M1/1017 ,  A61M1/1031 ,  A61M1/1036 ,  A61M1/1086 ,  A61M1/122 ,  A61M2205/3303 ,  A61M2205/3507 ,  F04B35/04 ,  F04D7/04 ,  F04D13/024 ,  F04D13/0666 ,  F04D15/0088 ,  F04D29/041 ,  F04D29/0473 ,  F04D29/048 ,  F04D29/22 ,  F04D29/426 ,  F04D29/428 ,  H02P6/18

Abstract: A centrifugal pump system having an impeller rotating with first and second magnetic structures on opposite surfaces. A levitation magnetic structure is disposed at a first end of a pump housing having a levitating magnetic field for axially attracting the first magnetic structure. A multiphase magnetic stator at a second end of the pump housing generates a rotating magnetic field for axially and rotationally attracting the second magnetic structure. A commutator circuit provides a plurality of phase voltages to the stator. A sensing circuit determines respective phase currents. A controller calculates successive commanded values for the phase voltages in response to the determined phase currents and a variable commutation angle. The angle is selected to correspond to an axial attractive force of the stator that maintains a levitation of the impeller at a centered position within the pumping chamber.

Abstract translation: 一种离心泵系统，其具有在相对表面上以第一和第二磁性结构旋转的叶轮。 悬浮磁性结构设置在具有用于轴向吸引第一磁性结构的悬浮磁场的泵壳体的第一端。 在泵壳的第二端处的多相磁性定子产生用于轴向和旋转地吸引第二磁性结构的旋转磁场。 换向器电路向定子提供多个相电压。 感测电路确定各个相电流。 控制器响应于所确定的相电流和可变换流角来计算相电压的连续命令值。 角度被选择为对应于定子的轴向吸引力，其保持叶轮在泵送室内的中心位置的悬浮。