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公开(公告)号:KR20180054427A
公开(公告)日:2018-05-24
申请号:KR20170126636
申请日:2017-09-28
Inventor: KIM SEOKJOONG , SONG DONG WOO , HONG YOUNG BIN , CHOI BYUNG OK , LEE JAE YOUNG , LEE JUNG MIN
IPC: C07K14/705 , A61K48/00 , C12N9/22 , C12N15/10 , C12N15/113 , C12N15/86
CPC classification number: C12N15/86 , C12N15/113 , C12N2310/20
Abstract: 본발명은 SC 기능조절및/또는 SC 기능장애로인한질환치료또는개선을위한, 인위적으로조작된 SC 기능조절인자및 이의이용에관한것이다. 보다구체적으로, SC 기능조절및/또는 SC 기능장애로인한질환치료또는개선을위한인위적으로조작된 SC 기능조절인자및/또는 SC 기능조절인자를인위적으로조작할수 있는조성물을포함하는, 인위적으로 SC 기능조절및/또는 SC 기능장애로인한질환치료또는개선할수 있는시스템에관한것이다. 구체적인양태로, 인위적으로조작된 PMP22 등의 SC 기능조절인자및/또는이의발현산물에의한 SC 기능조절시스템에관한것이다.
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公开(公告)号:KR20180018466A
公开(公告)日:2018-02-21
申请号:KR20170149914
申请日:2017-11-10
Applicant: TOOLGEN INCORPORATED
Inventor: KIM SEOKJOONG , KIM YOON YOUNG , YU HO SUNG , JUNG IN YOUNG , LEE JUNG MIN
CPC classification number: Y02A50/47
Abstract: 면역조절유전자가불활성화된면역세포, 이를포함하는약학조성물, 면역세포에서의면역조절유전자불활성화에적용가능한가이드 RNA, 상기가이드 RNA 또는이를암호화하는핵산분자와 RNA-가이드엔도뉴클레아제또는이를암호화하는핵산분자를포함하는면역세포유전체교정용조성물및 이를이용하는방법이제공된다.
Abstract translation: 免疫调节基因是失活的免疫细胞,含有它们的药物组合物,免疫调节eseoui基因的光施加到可活化引导RNA,引导RNA或核酸分子和RNA-指导编码所述核酸内切酶相同,或者它加密免疫细胞 以及使用它的方法。
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公开(公告)号:AU2022204029B2
公开(公告)日:2024-12-19
申请号:AU2022204029
申请日:2022-06-09
Applicant: TOOLGEN INCORPORATED
Inventor: KIM SEOKJOONG , KOO OKJAE , JUNG MIN HEE , KIM YESEUL
IPC: C12N15/82 , C12N9/02 , C12N9/22 , C12N15/10 , C12N15/113
Abstract: The present invention relates to an artificially manipulated unsaturated fatty acid biosynthesis-associated factor and use thereof to increase the content of a specific unsaturated fatty acid of a plant body. More particularly, the present 5 invention relates to a system capable of artificially controlling unsaturated fatty acid biosynthesis and a plant body produced thereby, which include an artificially manipulated unsaturated fatty acid biosynthesis-associated factor to control unsaturated fatty acid biosynthesis and a composition capable of artificially manipulating the factor. In a specific aspect, the present invention relates to 10 artificially manipulated unsaturated fatty acid biosynthesis-associated factors such as FAD2, FAD3, FAD6, FAD7 and FAD8 and/or an unsaturated fatty acid biosynthesis controlling system by an expression product thereof.
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公开(公告)号:AU2017358122B2
公开(公告)日:2022-12-22
申请号:AU2017358122
申请日:2017-09-28
Applicant: TOOLGEN INCORPORATED
Inventor: KIM SEOKJOONG , SONG DONG WOO , HONG YOUNG BIN , CHOI BYUNG OK , LEE JAE YOUNG , LEE JUNG MIN
IPC: C12N15/113 , A61K48/00 , C07K14/705 , C12N9/22 , C12N15/10 , C12N15/86
Abstract: The present invention relates to an artificially engineered SC function control factor for SC function control and/or the treatment or alleviation of a disease due to SC function disorder, and to a use thereof. More specifically, the present invention relates to a system capable of performing artificial SC function control and/or treating or alleviating a disease due to SC function disorder, the system comprising: an artificially engineered SC function control factor for SC function control and/or the treatment or alleviation of a disease due to SC function disorder; and/or a composition capable of artificially engineering an SC function control factor. In a specific aspect, the present invention relates to an SC function control system by an SC function control factor, such as artificially engineered PMP22, and/or an expression product thereof.
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公开(公告)号:AU2017313616B2
公开(公告)日:2022-12-08
申请号:AU2017313616
申请日:2017-08-21
Applicant: INST FOR BASIC SCIENCE , SEOUL NATIONAL UNIV HOSPITAL , SEOUL NATIONAL UNIV R&DB FOUNDATION , TOOLGEN INCORPORATED
Inventor: KIM JEONG HUN , PARK SUNG WOOK , KIM SEOKJOONG , SONG DONG WOO
IPC: C12N15/12 , A61K48/00 , C07K14/47 , C07K14/475 , C07K14/515 , C12N9/22 , C12N15/10 , C12N15/113 , C12N15/86 , C12N15/90
Abstract: The present invention relates to artificially engineered angiogenesis-related factors and a use thereof, for angiogenesis regulation. More specifically, the present invention relates to a system that can artificially regulate angiogenesis, including artificially engineered angiogenesis-related factors to regulate angiogenesis and/or a composition capable of artificially engineering angiogenesis-related factors. In specific aspects, the present invention relates to artificially engineered angiogenesis-related factors such as VEGFA, HIF1A, ANGPT2, EPAS1, ANGPTL4, etc. and/or an angiogenesis regulatory system by their expression products thereof.
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