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公开(公告)号:AT147747T
公开(公告)日:1997-02-15
申请号:AT92305328
申请日:1992-06-10
Applicant: TORAY INDUSTRIES
Inventor: HATA GO , KANEKO TATSUYA , KAWAI HIDEKI , MUTOH MASATO , HASHIMOTO HIDEYUKI
IPC: A61K31/555 , A61P35/00 , C07F15/00 , C07D307/46
Abstract: A platinum(II) complex is represented by the general formula (A), in which R1 represents a hydrocarbon radical having 1 to 10 carbon atoms, R2 and R3 each represent a hydrogen atom or a hydrocarbon radical of 1 to 10 carbon atoms, or R2 and R3, together, may form -(CH2)4- or -(CH2)5-, and X R2 and R3, together, may form -(CH2)4- or -(CH2)5-, and X and Y each represent an ammonia molecule or a monodentate and Y each represent an ammonia molecule or a monodentate amine having 1 to 7 carbon atoms or X and Y, together, amine having 1 to 7 carbon atoms or X and Y, together, may form a bidentate diamine having 2 to 10 carbon atoms. The compounds are useful for treating tumors.
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公开(公告)号:FI913786A0
公开(公告)日:1991-08-09
申请号:FI913786
申请日:1991-08-09
Applicant: TORAY INDUSTRIES
Inventor: HATA GO , MUTOH MASATO , HASHIMOTO HIDEYUKI
IPC: A23K20/195 , A61K31/495 , A61K31/555 , A61K33/24 , C07F15/00 , C07F
Abstract: Gamma lolactone platinum complexes of formula (I) are new: R1 = 1-5C hydrocarbyl; R2,R3 = H or 1-3C hydrocarbyl; and the configuration of the 1,2-diaminocyclohexane ring is cis, trans-l or trans-d.
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公开(公告)号:ES2096721T3
公开(公告)日:1997-03-16
申请号:ES92305328
申请日:1992-06-10
Applicant: TORAY INDUSTRIES
Inventor: HATA GO , KANEKO TATSUYA , KAWAI HIDEKI , MUTOH MASATO , HASHIMOTO HIDEYUKI
IPC: A61K31/555 , A61P35/00 , C07F15/00 , C07D307/46
Abstract: A platinum(II) complex is represented by the general formula (A), in which R1 represents a hydrocarbon radical having 1 to 10 carbon atoms, R2 and R3 each represent a hydrogen atom or a hydrocarbon radical of 1 to 10 carbon atoms, or R2 and R3, together, may form -(CH2)4- or -(CH2)5-, and X R2 and R3, together, may form -(CH2)4- or -(CH2)5-, and X and Y each represent an ammonia molecule or a monodentate and Y each represent an ammonia molecule or a monodentate amine having 1 to 7 carbon atoms or X and Y, together, amine having 1 to 7 carbon atoms or X and Y, together, may form a bidentate diamine having 2 to 10 carbon atoms. The compounds are useful for treating tumors.
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公开(公告)号:DE69216693D1
公开(公告)日:1997-02-27
申请号:DE69216693
申请日:1992-06-10
Applicant: TORAY INDUSTRIES
Inventor: HATA GO , KANEKO TATSUYA , KAWAI HIDEKI , MUTOH MASATO , HASHIMOTO HIDEYUKI
IPC: A61K31/555 , A61P35/00 , C07F15/00 , C07D307/46
Abstract: A platinum(II) complex is represented by the general formula (A), in which R1 represents a hydrocarbon radical having 1 to 10 carbon atoms, R2 and R3 each represent a hydrogen atom or a hydrocarbon radical of 1 to 10 carbon atoms, or R2 and R3, together, may form -(CH2)4- or -(CH2)5-, and X R2 and R3, together, may form -(CH2)4- or -(CH2)5-, and X and Y each represent an ammonia molecule or a monodentate and Y each represent an ammonia molecule or a monodentate amine having 1 to 7 carbon atoms or X and Y, together, amine having 1 to 7 carbon atoms or X and Y, together, may form a bidentate diamine having 2 to 10 carbon atoms. The compounds are useful for treating tumors.
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公开(公告)号:DK0518645T3
公开(公告)日:1997-02-03
申请号:DK92305328
申请日:1992-06-10
Applicant: TORAY INDUSTRIES
Inventor: HATA GO , KANEKO TATSUYA , KAWAI HIDEKI , MUTOH MASATO , HASHIMOTO HIDEYUKI
IPC: A61K31/555 , A61P35/00 , C07F15/00 , C07D307/46
Abstract: A platinum(II) complex is represented by the general formula (A), in which R1 represents a hydrocarbon radical having 1 to 10 carbon atoms, R2 and R3 each represent a hydrogen atom or a hydrocarbon radical of 1 to 10 carbon atoms, or R2 and R3, together, may form -(CH2)4- or -(CH2)5-, and X R2 and R3, together, may form -(CH2)4- or -(CH2)5-, and X and Y each represent an ammonia molecule or a monodentate and Y each represent an ammonia molecule or a monodentate amine having 1 to 7 carbon atoms or X and Y, together, amine having 1 to 7 carbon atoms or X and Y, together, may form a bidentate diamine having 2 to 10 carbon atoms. The compounds are useful for treating tumors.
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公开(公告)号:AT143967T
公开(公告)日:1996-10-15
申请号:AT91900371
申请日:1990-12-11
Applicant: TORAY INDUSTRIES
Inventor: HATA GO , MUTOH MASATO A , HASHIMOTO HIDEYUKI
IPC: A23K20/195 , A61K31/495 , A61K31/555 , A61K33/24 , C07F15/00
Abstract: Gamma lolactone platinum complexes of formula (I) are new: R1 = 1-5C hydrocarbyl; R2,R3 = H or 1-3C hydrocarbyl; and the configuration of the 1,2-diaminocyclohexane ring is cis, trans-l or trans-d.
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公开(公告)号:NO913108L
公开(公告)日:1991-10-10
申请号:NO913108
申请日:1991-08-09
Applicant: TORAY INDUSTRIES
Inventor: HATA GO , MUTOH MASATO , HASHIMOTO HIDEYUKI
IPC: A23K20/195 , A61K31/495 , A61K31/555 , A61K33/24 , C07F15/00
Abstract: Gamma lolactone platinum complexes of formula (I) are new: R1 = 1-5C hydrocarbyl; R2,R3 = H or 1-3C hydrocarbyl; and the configuration of the 1,2-diaminocyclohexane ring is cis, trans-l or trans-d.
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公开(公告)号:NO913108D0
公开(公告)日:1991-08-09
申请号:NO913108
申请日:1991-08-09
Applicant: TORAY INDUSTRIES
Inventor: HATA GO , MUTOH MASATO , HASHIMOTO HIDEYUKI
IPC: A23K20/195 , A61K31/495 , A61K31/555 , A61K33/24 , C07F15/00
Abstract: Gamma lolactone platinum complexes of formula (I) are new: R1 = 1-5C hydrocarbyl; R2,R3 = H or 1-3C hydrocarbyl; and the configuration of the 1,2-diaminocyclohexane ring is cis, trans-l or trans-d.
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公开(公告)号:DE69216693T2
公开(公告)日:1997-05-07
申请号:DE69216693
申请日:1992-06-10
Applicant: TORAY INDUSTRIES
Inventor: HATA GO , KANEKO TATSUYA , KAWAI HIDEKI , MUTOH MASATO , HASHIMOTO HIDEYUKI
IPC: A61K31/555 , A61P35/00 , C07F15/00 , C07D307/46
Abstract: A platinum(II) complex is represented by the general formula (A), in which R1 represents a hydrocarbon radical having 1 to 10 carbon atoms, R2 and R3 each represent a hydrogen atom or a hydrocarbon radical of 1 to 10 carbon atoms, or R2 and R3, together, may form -(CH2)4- or -(CH2)5-, and X R2 and R3, together, may form -(CH2)4- or -(CH2)5-, and X and Y each represent an ammonia molecule or a monodentate and Y each represent an ammonia molecule or a monodentate amine having 1 to 7 carbon atoms or X and Y, together, amine having 1 to 7 carbon atoms or X and Y, together, may form a bidentate diamine having 2 to 10 carbon atoms. The compounds are useful for treating tumors.
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公开(公告)号:NO913108A
公开(公告)日:1991-10-10
申请号:NO913108
申请日:1991-08-09
Applicant: TORAY INDUSTRIES
Inventor: HATA GO , MUTOH MASATO , HASHIMOTO HIDEYUKI
IPC: A23K1/17 , A23K1/18 , A61K31/495 , A61K31/555 , A61K33/24 , C07F15/00
CPC classification number: C07F15/0093
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