中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

61 records (took 0.025 seconds)

    Composición inmunogénica
    1.
    发明专利
    Composición inmunogénica 未知

    公开(公告)号：ES2755361T3

    公开(公告)日：2020-04-22

    申请号：ES10746311

    申请日：2010-02-26

    Applicant: TORAY INDUSTRIES

    Inventor： NISHIO REIJI ,  IDA NOBUO

    IPC: A61K39/39

    Abstract: Composición inmunogénica que comprende como ingrediente eficaz un complejo de micropartículas antígeno-adyuvante que contiene un antígeno encapsulado en una micropartícula adyuvante compuesta por un polímero anfifílico cuyo segmento hidrófobo es un ácido poli(láctico-co-glicólico), y el segmento hidrófilo del polímero anfifílico es un polisacárido refractario.

    CELL-PENETRATING PEPTIDES
    3.
    发明专利
    CELL-PENETRATING PEPTIDES 未知

    公开(公告)号：CA2762551C

    公开(公告)日：2016-11-22

    申请号：CA2762551

    申请日：2010-05-19

    Applicant: TORAY INDUSTRIES

    Inventor： MORISHITA MARIKO ,  TAKAYAMA KOZO ,  NISHIO REIJI ,  IDA NOBUO

    IPC: C07K7/08 ,  A61K9/38 ,  A61K38/28

    Abstract: A cell-penetrating peptide described in any of (A) to (D) below gives cell membrane permeability and further transmucosal absorbability to a physiologically active substance: (A) a peptide having the amino acid sequence represented by SEQ ID NO: 1; (B) a peptide having an amino acid sequence which is the same as the amino acid sequence represented by SEQ ID NO:1 except that one or several basic amino acids are substituted, deleted, inserted and/or added, which peptide has cell membrane permeability; (C) a peptide having an amino acid sequence which is the same as the amino acid sequence represented by SEQ ID NO:1 except that 1 to 5 amino acids are substituted, deleted, inserted and/or added, which peptide has cell membrane permeability; (D) a peptide having: an amino acid sequence represented by the reverse sequence of any of (A) to (C); an amino acid sequence which is the same as the amino acid sequence represented by the reverse sequence of (A) except that one or several basic amino acids are substituted, deleted, inserted and/or added; or an amino acid sequence which is the same as the amino acid sequence represented by the reverse sequence of (A) except that 1 to 5 amino acids are substituted, deleted, inserted and/or added; which peptide has cell membrane permeability.

    Pharmaceutical composition for transnasal administration
    7.
    发明专利
    Pharmaceutical composition for transnasal administration 未知

    公开(公告)号：AU2009218060A1

    公开(公告)日：2009-09-03

    申请号：AU2009218060

    申请日：2009-02-27

    Applicant: TORAY INDUSTRIES

    Inventor： NISHIO REIJI ,  IDA NOBUO ,  TAKAYAMA KOZO ,  MORISHITA MARIKO

    IPC: A61K45/00 ,  A61K38/21 ,  A61K38/28 ,  A61K47/42 ,  A61P43/00

    Abstract: By a pharmaceutical composition for nasal administration comprising a hydrophilic bioactive substance and any one of (a) to (c) below, a hydrophilic bioactive substance having a low transmucosal absorption capability which has conventionally been able to be administered by only injection can be nasally administered. Such a pharmaceutical composition is useful for improvement of the pain and the inconvenience of patients caused by administration by injection. (a) A peptide having the amino acid sequence shown in SEQ ID NO: 1. (b) A peptide having the same amino acid sequence as shown in SEQ ID NO: except that one or several amino acids are deleted, substituted and/or added, the peptide having nasal mucosal permeability. (c) A peptide having an amino acid sequence represented by the reverse sequence of (a) or (b), the peptide having nasal mucosal permeability.

Patent Agency Ranking