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公开(公告)号:CA3108045A1
公开(公告)日:2020-02-06
申请号:CA3108045
申请日:2019-07-29
Applicant: TORAY INDUSTRIES
Inventor: KAGAWA YUSUKE , HIRAMATSU SHINGO , YAMADA KATSUSHIGE
Abstract: The present invention relates to: a mutant of a trichoderma filamentous fungus having a mutation that results in lost or lowered function of a beta-adaptin large subunit, or a mutation in an amino acid sequence that forms the beta-adaptin large subunit; and a method for producing a protein while maintaining a low viscosity in a culture solution during culturing by using the mutant.
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公开(公告)号:AU2019242425A1
公开(公告)日:2020-10-15
申请号:AU2019242425
申请日:2019-03-25
Applicant: TORAY INDUSTRIES
Inventor: KAGAWA YUSUKE , SAITO HARUKA , HIRAMATSU SHINGO , YAMADA KATSUSHIGE
Abstract: The present invention relates to: a Trichoderma reesei mutant wherein a polypeptide comprising an amino acid sequence represented by SEQ ID NO:2 has a reduced function; and a method for enhanced production of a protein using the mutant.
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公开(公告)号:CA3111169A1
公开(公告)日:2020-03-05
申请号:CA3111169
申请日:2019-08-28
Applicant: TORAY INDUSTRIES
Inventor: KAGAWA YUSUKE , HIRAMATSU SHINGO , YAMADA KATSUSHIGE
Abstract: The present invention provides: a Trichoderma reesei mutant strain having such a mutation that the function of a polypeptide comprising the amino acid sequence represented by SEQ ID NO: 2 is lost or decreased; and a method for the high-throughput production of a protein, comprising culturing the mutant strain.
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公开(公告)号:AU2019277550B2
公开(公告)日:2025-03-06
申请号:AU2019277550
申请日:2019-05-30
Applicant: TORAY INDUSTRIES
Inventor: KAGAWA YUSUKE , HIRAMATSU SHINGO , YAMADA KATSUSHIGE
Abstract: The present invention relates to: a Trichoderma filamentous fungus mutant strain having reduced functionality of a polypeptide formed by an amino acid sequence of SEQ ID NO: 2; and a high-producing method for a protein by using the mutant strain.
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公开(公告)号:AU2019329357A1
公开(公告)日:2021-03-18
申请号:AU2019329357
申请日:2019-08-28
Applicant: TORAY INDUSTRIES
Inventor: KAGAWA YUSUKE , SAITO HARUKA , HIRAMATSU SHINGO , YAMADA KATSUSHIGE
Abstract: The present invention is a mutant strain of Trichoderma reesei in which the function of a polypeptide comprising an amino acid sequence represented by any of SEQ ID NOS: 4-6 is deleted or decreased, and a method for producing a high level of protein by culturing the mutant strain in medium containing lactose.
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公开(公告)号:AU2019331247A1
公开(公告)日:2021-03-18
申请号:AU2019331247
申请日:2019-08-28
Applicant: TORAY INDUSTRIES
Inventor: KAGAWA YUSUKE , HIRAMATSU SHINGO , YAMADA KATSUSHIGE
Abstract: The present invention provides: a
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公开(公告)号:AU2019313902A1
公开(公告)日:2021-02-18
申请号:AU2019313902
申请日:2019-07-29
Applicant: TORAY INDUSTRIES
Inventor: KAGAWA YUSUKE , HIRAMATSU SHINGO , YAMADA KATSUSHIGE
Abstract: The present invention relates to: a mutant of a trichoderma filamentous fungus having a mutation that results in lost or lowered function of a beta-adaptin large subunit, or a mutation in an amino acid sequence that forms the beta-adaptin large subunit; and a method for producing a protein while maintaining a low viscosity in a culture solution during culturing by using the mutant.
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公开(公告)号:CA3094606A1
公开(公告)日:2019-10-03
申请号:CA3094606
申请日:2019-03-25
Applicant: TORAY INDUSTRIES
Inventor: KAGAWA YUSUKE , SAITO HARUKA , HIRAMATSU SHINGO , YAMADA KATSUSHIGE
Abstract: The present invention relates to: a Trichoderma reesei mutant wherein a polypeptide comprising an amino acid sequence represented by SEQ ID NO:2 has a reduced function; and a method for enhanced production of a protein using the mutant.
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公开(公告)号:AU2019331247B9
公开(公告)日:2025-02-20
申请号:AU2019331247
申请日:2019-08-28
Applicant: TORAY INDUSTRIES
Inventor: KAGAWA YUSUKE , HIRAMATSU SHINGO , YAMADA KATSUSHIGE
Abstract: The present invention provides: a
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公开(公告)号:AU2019331247B2
公开(公告)日:2025-01-30
申请号:AU2019331247
申请日:2019-08-28
Applicant: TORAY INDUSTRIES
Inventor: KAGAWA YUSUKE , HIRAMATSU SHINGO , YAMADA KATSUSHIGE
Abstract: The present invention provides: a
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