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    PROCESS OF PRODUCING 1,4-BUTANEDIOL
    1.
    发明申请
    PROCESS OF PRODUCING 1,4-BUTANEDIOL 审中-公开
    生产1,4-丁二醇的方法

    公开(公告)号：WO2014170759A2

    公开(公告)日：2014-10-23

    申请号：PCT/IB2014001279

    申请日：2014-04-09

    Applicant: TORAY INDUSTRIES

    Inventor： KAWAMURA KENJI ,  MORITA IZUMI ,  ITO MASATERU ,  SAKAMI SATOSHI ,  MAKINO MASATAKA ,  YAMADA KATSUSHIGE ,  BURK MARK J ,  JAPS MICHAEL ,  CLARK WARREN

    IPC: C07C29/80

    CPC classification number: C07C29/80 ,  B01D3/143 ,  B01D3/145 ,  B01D3/34 ,  B01D15/361 ,  B01D61/025 ,  B01D2311/2623 ,  B01D2311/2669 ,  C07C67/08 ,  C08G63/183 ,  C07C31/207 ,  C07C69/82

    Abstract: A process produces 1,4-butanediol by purifying 1,4-butanediol originated from a fermentation broth, by which process 1,4-butanediol having properties suited as a material of producing a polyester is obtained, which 1,4-butanediol enables to reduce by-production of tetrahydrofuran during the esterification reaction and to reduce the delay in polymerization. The process of producing 1,4-butanediol includes adding an alkaline substance other than an ammonia or an amine to an aqueous 1,4-butanediol-containing solution originated from a fermentation broth; distilling the resulting mixture; and recovering a 1,4-butanediol- containing solution from the vapor flow.

    Abstract translation: 一种方法是通过纯化发酵液中的1,4-丁二醇来纯化生产1,4-丁二醇的方法，通过该方法可得到具有适合作为生产聚酯材料的性能的1,4-丁二醇，该1,4-丁二醇可使 在酯化反应期间减少四氢呋喃的副产物并减少聚合的延迟。 生产1,4-丁二醇的方法包括将不同于氨或胺的碱性物质加入到发酵液中的含1,4-丁二醇的水溶液中; 蒸馏所得混合物; 并从蒸气流中回收含有1,4-丁二醇的溶液。

    3.
    发明专利
    未知

    公开(公告)号：AT402179T

    公开(公告)日：2008-08-15

    申请号：AT01997196

    申请日：2001-11-22

    Applicant: TORAY INDUSTRIES

    Inventor： SAKAMI SATOSHI ,  KAWAI KOJI ,  MAEDA MASAYUKI ,  AOKI TAKUMI ,  UENO SHINYA

    IPC: C07D491/22 ,  A61K31/475 ,  A61K31/485 ,  A61P11/14 ,  A61P25/04 ,  A61P25/28 ,  A61P29/00 ,  A61P37/06 ,  A61P43/00

    Abstract: This invention relates to: an indole derivative or a pharmaceutically acceptable salt thereof represented by formula (I): wherein R is, for example, hydrogen or C1-5 alkyl; R is, for example, hydrogen or hydroxy; R is, for example, hydrogen or hydroxy, -Z- is a crosslinkage having 2 to 5 carbon atoms; m is an integer from 0 to 3; n is an integer from 0 to 10; R and R are, for example, fluoro or hydroxy; R is, for example, hydrogen or C1-5 alkyl; and R and R are bound to each other to form, for example, -O-; and a pharmaceutical composition comprising the same, particularly a drug acting on delta opioid receptor.

    5.
    发明专利
    未知

    公开(公告)号：ES2197953T3

    公开(公告)日：2004-01-16

    申请号：ES96932007

    申请日：1996-09-26

    Applicant: TORAY INDUSTRIES

    Inventor： NAGASE HIROSHI ,  KAWAI KOJI ,  ENDO TAKASHI ,  UENO SHINYA ,  MAEDA MASAYUKI ,  SAKAMI SATOSHI

    IPC: C07D491/22 ,  A61K31/475

    Abstract: The present invention relates to indole derivatives represented by the following compound 1 and the pharmacologically acceptable acid addition salt thereof. The compounds of the present invention were found to exhibit strong antitussive and analgesic actions as a result of pharmacological evaluation, and can be used in the pharmaceutical field as effective antitussives and analgesics.

    6.
    发明专利
    未知

    公开(公告)号：DE69628543D1

    公开(公告)日：2003-07-10

    申请号：DE69628543

    申请日：1996-09-26

    Applicant: TORAY INDUSTRIES

    Inventor： NAGASE HIROSHI ,  KAWAI KOJI ,  ENDO TAKASHI ,  UENO SHINYA ,  MAEDA MASAYUKI ,  SAKAMI SATOSHI

    IPC: C07D491/22 ,  A61K31/475

    Abstract: The present invention relates to indole derivatives represented by the following compound 1 and the pharmacologically acceptable acid addition salt thereof. The compounds of the present invention were found to exhibit strong antitussive and analgesic actions as a result of pharmacological evaluation, and can be used in the pharmaceutical field as effective antitussives and analgesics.

    ALCOHOL PRODUCTION METHOD
    9.
    发明专利
    ALCOHOL PRODUCTION METHOD 未知

    公开(公告)号：MY170308A

    公开(公告)日：2019-07-17

    申请号：MYPI2015702031

    申请日：2013-12-18

    Applicant: TORAY INDUSTRIES

    Inventor： YAMADA KATSUSHIGE ,  ITO MASATERU ,  KAWAMURA KENJI ,  SAKAMI SATOSHI

    Abstract: An alcohol production method whereby high quality alcohol can be easily and effectively produced includes a step in which an alcohol solution, which contains sugar and/or sugar alcohol as an impurity and an alcohol other than sugar alcohol as a main component, has the sugar and/or sugar alcohol adsorptively removed therefrom by contacting the alcohol solution with one type or a mixture of two or more types of adsorbents selected from zeolite, an ion-exchange resin, silica alumina, and alumina.

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