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公开(公告)号：PL2607482T3
公开(公告)日：2017-09-29
申请号：PL11818210
申请日：2011-08-17
Applicant: TORAY INDUSTRIES
Inventor： YOSHIMOTO MAKIKO , AKIYAMA HIDEO , NOBUMASA HITOSHI
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公开(公告)号：CA3091211A1
公开(公告)日：2019-08-22
申请号：CA3091211
申请日：2019-02-12
Applicant: TORAY INDUSTRIES , NAT CT GERIATRICS & GERONTOLOGY
Inventor： SUZUKI KANA , YOSHIMOTO MAKIKO , KAWAUCHI JUNPEI , SUDO HIROKO , KIDA YUHO , KOZONO SATOKO , KONDOU SATOSHI , NIIDA SHUMPEI , ASANOMI YUYA , SHIGEMIZU DAICHI , SAKURAI TAKASHI
Abstract: An embodiment according to the present invention provides a kit or device for detecting dementia, and a method for detecting dementia. An embodiment according to the present invention relates to: a kit or device for detecting dementia, the kit or device including a nucleic acid capable of specifically binding to miRNA or a complementary strand thereof in a sample from a subject; and a method for detecting dementia, the method including measuring said miRNA in vitro.
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公开(公告)号：AU2011291680B2
公开(公告)日：2014-01-09
申请号：AU2011291680
申请日：2011-08-17
Applicant: TORAY INDUSTRIES
Inventor： YOSHIMOTO MAKIKO , AKIYAMA HIDEO , NOBUMASA HITOSHI
IPC: C12N15/09
Abstract: Disclosed is a solution for extracting substantially pure RNA from a biological sample. A solution for extracting RNA from a biological sample containing RNA and at least DNA comprises (a) a phenol in an amount of more than 50 vol% relative to the total amount of the solution, (b) a polyhydric alcohol in an amount of 3-10 vol% relative to the total amount of the solution, (c) a guanidium salt at a concentration of 0.5-2.0 M relative to the total amount of the solution, (d) a thiocyanic acid salt at a concentration of 0.1-0.5 M relative to the total amount of the solution, and (e) a buffering agent for maintaining the solution at pH 4-6.
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公开(公告)号：CA2808265C
公开(公告)日：2016-09-06
申请号：CA2808265
申请日：2011-08-17
Applicant: TORAY INDUSTRIES
Inventor： YOSHIMOTO MAKIKO , AKIYAMA HIDEO , NOBUMASA HITOSHI
Abstract: A solution for extracting substantially pure RNA from a biological sample is disclosed. The solution for extracting RNA from a biological sample containing RNA and at least DNA comprises: (a) phenol in an amount of more than 50% by volume based on the total amount of the solution; (b) a polyol in an amount of 3 to 10% by volume based on the total amount of the solution; (c) a guanidinium salt at a concentration of 0.5 to 2.0 M based on the total amount of the solution; (d) a thiocyanate at a concentration of 0.1 to 0.5 M based on the total amount of the solution; and (e) a buffer for maintaining the pH of the solution at 4 to 6.
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公开(公告)号：CA2808265A1
公开(公告)日：2012-02-18
申请号：CA2808265
申请日：2011-08-17
Applicant: TORAY INDUSTRIES
Inventor： YOSHIMOTO MAKIKO , AKIYAMA HIDEO , NOBUMASA HITOSHI
Abstract: Disclosed is a solution for extracting substantially pure RNA from a biological sample. A solution for extracting RNA from a biological sample containing RNA and at least DNA comprises (a) a phenol in an amount of more than 50 vol% relative to the total amount of the solution, (b) a polyhydric alcohol in an amount of 3-10 vol% relative to the total amount of the solution, (c) a guanidium salt at a concentration of 0.5-2.0 M relative to the total amount of the solution, (d) a thiocyanic acid salt at a concentration of 0.1-0.5 M relative to the total amount of the solution, and (e) a buffering agent for maintaining the solution at pH 4-6.
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Patent Agency Ranking
公开(公告)号：CA3019550A1
公开(公告)日：2017-10-05
申请号：CA3019550
申请日：2017-03-31
Applicant: TORAY INDUSTRIES , NAT CANCER CT
Inventor： YOSHIMOTO MAKIKO , KOZONO SATOKO , KAWAUCHI JUNPEI , KONDOU SATOSHI , NOBUMASA HITOSHI , OCHIYA TAKAHIRO , NARITA YOSHITAKA , OHNO MAKOTO
IPC: C12N15/113 , C12M1/00 , C12N15/09 , C12Q1/68 , G01N33/50
Abstract: The present invention provides a kit or a device for detecting a malignant brain tumor, and a method of detecting the same. The present invention pertains to the following: a kit or a device for detecting a malignant brain tumor, where the kit or device includes a nucleic acid capable of binding specifically to a particular miRNA in a sample from a test subject; and a method for detecting a malignant brain tumor, where the method includes in vitro measurement of the miRNA.
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公开(公告)号：ES2622964T3
公开(公告)日：2017-07-10
申请号：ES11818210
申请日：2011-08-17
Applicant: TORAY INDUSTRIES
Inventor： YOSHIMOTO MAKIKO , AKIYAMA HIDEO , NOBUMASA HITOSHI
Abstract: Solución para la extracción de ARN de una muestra biológica que contiene ARN y, como mínimo, ADN, comprendiendo dicha solución: (a) fenol en una cantidad de no menos del 53% en volumen basada en la cantidad total de dicha solución; (b) un poliol en una cantidad del 3 al 10% en volumen basada en la cantidad total de dicha solución; (c) una sal de guanidinio a una concentración de 0,5 a 2,0 M basada en la cantidad total de dicha solución; (d) un tiocianato a una concentración de 0,1 a 0,5 M basada en la cantidad total de dicha solución, en la que en los casos en los que la solución comprenda tiocianato de guanidinio, la concentración de tiocianato de guanidinio está incluida en la concentración de la sal de guanidinio y no está incluida en la concentración de tiocianato; y (e) un tampón para mantener el pH de dicha solución entre 4 y 6.
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公开(公告)号：BR112013003528A2
公开(公告)日：2016-06-28
申请号：BR112013003528
申请日：2011-08-17
Applicant: TORAY INDUSTRIES
Inventor： AKIYAMA HIDEO , NOBUMASA HITOSHI , YOSHIMOTO MAKIKO
IPC: C12N15/09
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公开(公告)号：CA3098105A1
公开(公告)日：2019-10-31
申请号：CA3098105
申请日：2019-04-25
Applicant: TORAY INDUSTRIES , NAT CANCER CT
Inventor： YOSHIMOTO MAKIKO , SUDO HIROKO , KOZONO SATOKO , KAWAUCHI JUNPEI , OCHIYA TAKAHIRO , FUJIMOTO HIROYUKI , USUBA WATARU , MATSUZAKI JUNTARO
IPC: C12Q1/6886 , C12M1/00 , C12N15/09 , C12N15/113 , C12Q1/6813 , C12Q1/6837
Abstract: This invention according to one embodiment provides a kit, a device, and a method for detecting bladder cancer. This invention according to one embodiment relates to: a kit or a device that is for detecting bladder cancer and that contains a nucleic acid capable of selectively binding with the miRNA, or a complementary strand thereof, in a sample of a subject; as well as to a method for detecting bladder cancer, comprising in vitro determination of the miRNA.
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公开(公告)号：DK2607482T3
公开(公告)日：2017-07-03
申请号：DK11818210
申请日：2011-08-17
Applicant: TORAY INDUSTRIES
Inventor： YOSHIMOTO MAKIKO , AKIYAMA HIDEO , NOBUMASA HITOSHI
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