公开(公告)号：US20240221423A1

公开(公告)日：2024-07-04

申请号：US18225676

申请日：2023-07-24

Applicant: Zhongshan Ophthalmic Center, Sun Yat-Sen University ,  Tsinghua University

Inventor： Ruixin Wang ,  Haotian Lin ,  Feng Xu ,  Xinping Yu ,  Junfeng Lyu

IPC: G06V40/18 ,  G06V10/26 ,  G06V10/82 ,  G06V20/40 ,  G06V40/16

CPC classification number: G06V40/193 ,  G06V10/26 ,  G06V10/82 ,  G06V20/46 ,  G06V40/171

Abstract: Disclosed are a method and apparatus for measuring a gaze difference based on gaze estimation. Video data of a testee gazing at a visual target is obtained, and a face image sequence is obtained from the video data. The face image sequence is input into a first neural network for key frame extraction to obtain a first and second gaze position face image. The face images are input into a second neural network for facial feature point extraction. Cropping is performed based on facial feature point coordinates to obtain a first and second eye region image. A gaze difference estimation network is trained to obtain a trained gaze difference estimation network. The first and second eye region images are input into the trained gaze difference estimation network to obtain a predicted gaze difference between the first and second eye region images.

公开(公告)号：US20240221163A1

公开(公告)日：2024-07-04

申请号：US18221897

申请日：2023-07-14

Applicant: Zhongshan Ophthalmic Center, Sun Yat-Sen University ,  Tsinghua University

Inventor： Ruixin Wang ,  Haotian Lin ,  Feng Xu ,  Xinping Yu ,  Junfeng Lyu

IPC: G06T7/00 ,  A61B3/08 ,  G06T3/60 ,  G06T7/73

CPC classification number: G06T7/0016 ,  A61B3/085 ,  G06T3/60 ,  G06T7/74 ,  G06T7/75 ,  G06T2200/04 ,  G06T2207/20081 ,  G06T2207/20084 ,  G06T2207/30041 ,  G06T2207/30201

Abstract: Disclosed is a method and apparatus for measuring a deviation angle of a gaze position based on 3D reconstruction. A face image sequence of a testee is acquired. Covering conditions of the face image sequence are obtained. Key frame images are determined and input into a second neural network to obtain feature point heat maps that are converted into facial feature point coordinates. An objective function is constructed. A head pose corresponding to the key frame images is obtained. An eyeball position is initialized. An eyeball rotation angle of a reference gaze position is set as a preset angle. 3D coordinates of an eyeball in a reference gaze position image in a head coordinate system is solved. 3D coordinates of an eyeball in a to-be-measured image in the head coordinate system are fixed. An eyeball rotation angle is solved. A deviation angle of a gaze position is obtained.

公开(公告)号：US20230076853A1

公开(公告)日：2023-03-09

申请号：US17548486

申请日：2021-12-10

Applicant: Zhongshan Ophthalmic Center, Sun Yat-Sen University ,  Tsinghua University

Inventor： Haotian Lin ,  Feng Xu ,  Yahan Yang ,  Ruixin Wang ,  Junfeng Lyu

IPC: G06F21/60 ,  G06T5/00 ,  G06T7/00 ,  G06T7/11

Abstract: A method and an apparatus for protecting privacy of an ophthalmic patient and a storage medium are disclosed. The method includes: acquiring an examination video of the ophthalmic patient; extracting image features of each frame of images in the examination video, performing region division on each frame of the images according to position information of organs in the image features, and obtaining a region to be precisely reconstructed and a region to be roughly reconstructed according to a region division result; performing three-dimensional (3D) reconstruction on the region to be precisely reconstructed and the region to be roughly reconstructed, to obtain 3D reconstruction data corresponding to each frame of the images; and rendering all the 3D reconstruction data into a 3D reconstruction video.

公开(公告)号：US10400279B2

公开(公告)日：2019-09-03

申请号：US15503428

申请日：2015-08-31

Applicant: Tsinghua University ,  Singapore Institute for Clinical Sciences, A-STAR

Inventor： Wei Xie ,  Qiangzong Yin ,  Jingyi Wu ,  Feng Xu ,  Xu Peng

IPC: C12Q1/6874 ,  C12N15/10 ,  C12Q1/6806 ,  C40B50/06

Abstract: A method for constructing a sequencing library based on a single-stranded DNA molecule is provided comprising: (1) forming a poly(C)n tail at a 3′-terminus of the single-stranded DNA molecule, to obtain a single-stranded DNA molecule with the poly(C)n tail with n representing a number of base C, and n being an integer ranging from 5 to 30; (2) obtaining a double-stranded DNA molecule by using an extension primer based on the single-stranded DNA molecule with the poly(C)n tail, with the extension primer comprising a H(G)m unit at a 3′-terminus thereof, H being base A, base T or base C, m being a number of base G, and m being an integer ranging from 5 to 15; and (3) ligating an adapter to one terminus of the double-stranded DNA molecule remote from the H(G)m unit, and amplifying the resulting ligation product to obtain an amplification product forming the sequencing library.

公开(公告)号：US12026263B2

公开(公告)日：2024-07-02

申请号：US17548486

申请日：2021-12-10

Applicant: Zhongshan Ophthalmic Center, Sun Yat-Sen University ,  Tsinghua University

Inventor： Haotian Lin ,  Feng Xu ,  Yahan Yang ,  Ruixin Wang ,  Junfeng Lyu

IPC: G06T7/00 ,  G06F21/60 ,  G06T5/70 ,  G06T5/73 ,  G06T7/11

CPC classification number: G06F21/60 ,  G06T5/70 ,  G06T5/73 ,  G06T7/0012 ,  G06T7/11 ,  G06T2207/30041

Abstract: A method and an apparatus for protecting privacy of an ophthalmic patient and a storage medium are disclosed. The method includes: acquiring an examination video of the ophthalmic patient; extracting image features of each frame of images in the examination video, performing region division on each frame of the images according to position information of organs in the image features, and obtaining a region to be precisely reconstructed and a region to be roughly reconstructed according to a region division result; performing three-dimensional (3D) reconstruction on the region to be precisely reconstructed and the region to be roughly reconstructed, to obtain 3D reconstruction data corresponding to each frame of the images; and rendering all the 3D reconstruction data into a 3D reconstruction video.

公开(公告)号：US11594623B2

公开(公告)日：2023-02-28

申请号：US17058211

申请日：2018-08-03

Applicant: TSINGHUA UNIVERSITY

Inventor： Feng Xu ,  Bin Gao ,  Xinyi Li ,  Huaqiang Wu ,  He Qian

IPC: H01L29/775 ,  H01L29/06 ,  H01L29/165 ,  H01L29/66 ,  H01L29/78 ,  H01L29/10 ,  H01L29/423 ,  H01L29/786 ,  B82Y10/00 ,  H01L29/417

Abstract: A nanowire transistor and a manufacture method thereof are provided. The nanowire transistor includes a semiconductor wire, a semiconductor layer, a source electrode and a drain electrode. The semiconductor wire includes a first semiconductor material and includes a source region, a drain region, and a channel region, along an axial direction of the semiconductor wire, the channel region is between the source region and the drain region; the semiconductor layer includes a second semiconductor material and covers the channel region of the semiconductor wire; the source electrode is in the source region of the semiconductor wire and is in direct contact with the source region of the semiconductor wire, and the drain electrode is in the drain region of the semiconductor wire and is in direct contact with the drain region of the semiconductor wire.