公开(公告)号：WO2008052332A1

公开(公告)日：2008-05-08

申请号：PCT/CA2007/001942

申请日：2007-10-31

Applicant: TSO3 INC. ,  TURCOT, Richard ,  ROBITAILLE, Simon ,  DUFRESNE, Sylvie

Inventor： TURCOT, Richard ,  ROBITAILLE, Simon ,  DUFRESNE, Sylvie

IPC: A61L2/20 ,  A61L2/07

CPC classification number: A61L2/202 ,  C01B13/11 ,  C01B2201/62 ,  C01B2201/70 ,  C01B2201/80 ,  C01B2201/90 ,  Y10S422/906 ,  Y10S422/907

Abstract: The sterilization method disclosed includes the steps of - providing a sterilization chamber; - placing the article into the sterilization chamber; - sealing the sterilization chamber; - equalizing the temperature of the article and the sterilization atmosphere while the chamber is sealed; - applying a vacuum of a preselected vacuum pressure to the sterilization chamber; - supplying water vapour to the sterilization chamber under vacuum; - supplying ozone-containing gas to the sterilization chamber; - maintaining the sterilization chamber sealed for a preselected treatment period; and - releasing the vacuum in the sterilization chamber; whereby a vacuum pressure is used which lowers the boiling temperature of water in the sterilization chamber below the temperature in the sterilization chamber. The temperature equalization step is carried out while the chamber is sealed to prevent localized condensation of water during the subsequent step of supplying water vapour into the chamber.

Abstract translation: 所公开的消毒方法包括以下步骤：提供灭菌室; - 将物品放入灭菌室; - 密封灭菌室; - 在室被密封的同时均衡制品的温度和灭菌气氛; - 将预选真空压力的真空施加到所述灭菌室; - 在真空下向灭菌室供水蒸汽; - 向灭菌室供应含臭氧气体; - 将灭菌室保持密封以进行预选的治疗期; 和 - 释放灭菌室中的真空; 由此使用真空压力，其将灭菌室中的水的沸腾温度降低到灭菌室内的温度以下。 在室被密封的同时进行温度均衡步骤，以防止在将水蒸汽供应到室中的后续步骤期间水的局部冷凝。

公开(公告)号：WO2003039607A1

公开(公告)日：2003-05-15

申请号：PCT/CA2002/001720

申请日：2002-11-08

Applicant: TSO3 INC.

Inventor： ROBITAILLE, Simon ,  SIMARD, Mario ,  FOURNIER, Stephane ,  DUFRESNE, Sylvie ,  TURCOT, Richard

IPC: A61L2/20

CPC classification number: A61L2/20 ,  A61L2/202 ,  A61L2/24

Abstract: The sterilization method disclosed includes the steps of providing a sterilization chamber (10); - placing the article into the sterilization chamber; - equalizing the temperature of the article and the sterilization atmosphere; sealing the sterilization chamber; -applying a vacuum (40) of a preselected vacuum pressure to the sterilization chamber; - supplying water vapour (30) to the sterilization chamber under vacuum; - supplying ozone-containing gas (22) to the sterilization chamber; - maintaining the sterilization chamber sealed for a preselected treatment period; and - releasing the vacuum in the sterilization chamber; whereby a vacuum pressure is used which lowers the boiling temperature of water in the sterilization chamber below the temperature in the sterilization chamber. One or more ventilating cycles can be added to the preferred method for removing the remaining ozone and humidity from the sterilization chamber. Single cycle sterilization with ozone is more efficient and provides for a shorter sterilization cycle than with ETO and requires few changes in user habits. Moreover, the ozone-based process in accordance with the invention is compatible for use with current packaging, such as sterile pouches and rigid containers. The sterilization process is simple and substantially avoids human errors caused by false interpretation and handling. The ozone sterilization method of the invention requires substantially no aeration or cooling down of sterilized instruments so that they can be used immediately following the sterilization cycle. This allows hospitals to reduce the cost of maintaining expensive medical device inventories.

Abstract translation: 所公开的杀菌方法包括提供消毒室（10）的步骤。 - 将物品放入灭菌室; - 均衡制品的温度和灭菌气氛; 密封灭菌室; 将预选真空压力的真空（40）施加到所述灭菌室; - 在真空下向灭菌室供应水蒸汽（30） - 向所述消毒室供应含臭氧气体（22）; - 将灭菌室保持密封以进行预选的治疗期; 和 - 释放灭菌室中的真空; 由此使用真空压力，其将灭菌室中的水的沸腾温度降低到灭菌室内的温度以下。 可以将一个或多个通气循环添加到用于从灭菌室去除剩余的臭氧和湿度的优选方法中。 使用臭氧进行单循环灭菌更有效，并且提供比ETO更短的灭菌周期，并且对用户习惯的改变很少。 此外，根据本发明的基于臭氧的方法可与目前的包装（例如无菌袋和刚性容器）一起使用。 灭菌过程简单，大大避免了错误解释和处理造成的人为错误。 本发明的臭氧灭菌方法基本上不需要对灭菌器具进行通气或冷却，使得它们可以在灭菌周期后立即使用。 这样医院就可以降低维护昂贵的医疗设备库存的成本。

公开(公告)号：EP1175230A1

公开(公告)日：2002-01-30

申请号：EP00901431.7

申请日：2000-01-24

Applicant: Technologies of Sterilization with Ozone TSO3 Inc.

Inventor： SIMARD, Mario ,  FOURNIER, Stéphane ,  DUFRESNE, Sylvie ,  TURCOT, Richard ,  ROBITAILLE, Simon

IPC: A61L2/20 ,  A61L2/26

CPC classification number: A61L2/202 ,  A61L2/24

Abstract: The sterilization method disclosed includes the steps of providing a sterilization chamber; placing the article into the sterilization chamber; sealing the sterilization chamber; applying a vacuum of a preselected vacuum pressure to the sterilization chamber; supplying water vapour to the sterilization chamber under vacuum; supplying ozone-containing gas to the sterilization chamber; maintaining the sterilization chamber sealed for a preselected treatment period; and releasing the vacuum in the sterilization chamber, whereby a vacuum pressure is used which lowers the boiling temperature of water in the sterilization chamber below the temperature in the sterilization chamber. One or more ventilating cycles can be added to the preferred method for removing the remaining ozone and humidity from the sterilization chamber. Single cycle sterilization with ozone is more efficient and provides for a shorter sterilization cycle than with ETO and requires few changes in user habits. Moreover, the ozone-based process in accordance with the invention is compatible for use with current packaging, such as sterile pouches and rigid containers. The sterilization process is simple and substantially avoids human errors caused by false interpretation and handling. The ozone sterilization method of the invention requires substantially no aeration or cooling down of sterilized instruments so that they can be used immediately following the sterilization cycle. This allows hospitals to reduce the cost of maintaining expensive medical device inventories.

公开(公告)号：EP2091573A1

公开(公告)日：2009-08-26

申请号：EP07816092.6

申请日：2007-10-31

Applicant: TSO3 Inc.

Inventor： TURCOT, Richard ,  ROBITAILLE, Simon ,  DUFRESNE, Sylvie

IPC: A61L2/20 ,  A61L2/07

CPC classification number: A61L2/202 ,  C01B13/11 ,  C01B2201/62 ,  C01B2201/70 ,  C01B2201/80 ,  C01B2201/90 ,  Y10S422/906 ,  Y10S422/907

Abstract: The sterilization method disclosed includes the steps of - providing a sterilization chamber; - placing the article into the sterilization chamber; - sealing the sterilization chamber; - equalizing the temperature of the article and the sterilization atmosphere while the chamber is sealed; - applying a vacuum of a preselected vacuum pressure to the sterilization chamber; - supplying water vapour to the sterilization chamber under vacuum; - supplying ozone-containing gas to the sterilization chamber; - maintaining the sterilization chamber sealed for a preselected treatment period; and - releasing the vacuum in the sterilization chamber; whereby a vacuum pressure is used which lowers the boiling temperature of water in the sterilization chamber below the temperature in the sterilization chamber. The temperature equalization step is carried out while the chamber is sealed to prevent localized condensation of water during the subsequent step of supplying water vapour into the chamber.